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HUMAN BIOLOGY

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Title: HUMAN BIOLOGY


1
HUMAN BIOLOGY
2
WHY?
  • To learn about ourselves, our culture
  • To learn the relationship between form function
  • Study the parts to understand the whole body
  • To become familiar with terminology that
    describes the structures processes associated
    with the human body

3
CULTURE the reasons for it
  • CULTURE Social influences human behavior
  • Why is culture important?
  • To learn from the experiences of others
  • Its carried on through language big brains
  • Its faster acting easier to observe than the
    evolution of anatomy physiology

4
WHAT IS BIOLOGY?
  • Biology comes from the Greek
  • Bios life
  • Logos to study
  • Biology is the study of life!

5
What Is the Meaning Of Life?Top 7 ways to tell
the living from the nonliving
  • 1 Cellular Organization
  • 2 Reproduction
  • 3 Metabolism
  • 4 Homeostasis
  • 5 Heredity
  • 6 Responsiveness
  • 7 Able to Grow Develop

6
If It Does NOT meet ALL 7
  • ITS NOT ALIVE!

7
CELLULAR ORGANIZATION
  • All living things are made up of 1 or more cells
  • Cells smallest unit capable of all life
    functions

8
REPRODUCTION
  • How all life forms make more of their own kind
    from 1 generation to the next
  • All living things (ORGANISMS) can reproduce

9
METABOLISM
  • Sum of all chemical reactions in an organism
  • Chemistry is necessary for life!
  • Balancing those chemical reactions
    HOMEOSTASIS

10
HOMEOSTASIS
  • The ability to maintain a relatively constant
    internal environment (at all levels of body
    organization) despite changes in the outside
    environment

11
EXAMPLES of HOMEOSTASIS
  • Body temperature
  • Water-mineral balance
  • Blood pressure
  • Sleep-wake cycle
  • Blood pH
  • Any physiological process with a
    negative-feedback system of control

12
Why Is Homeostasis Such A Big Deal?
  • Physiological processes can function only under a
    limited range of conditions
  • Goldilocks factor
  • EX--- Body temperature
  • 98.6º F or 37º C

13
HEREDITY
  • All organisms pass on traits from parent to
    offspring
  • GENES sets of inherited instructions for making
    proteins
  • MUTATION any change in a gene (DNA)
  • DNA code on genes for making proteins

14
RESPONSIVENESS(irritability)
  • 1 Detect information about the environment
  • 2 Process this information
  • 3 Respond appropriately

15
GROWTH DEVELOPMENT
  • GROWTH replace worn out cells


    increase in size
  • DEVELOPMENT advance, fulfill with time
  • mature

16
METABOLISM
  • Sum of all chemical reactions within living cells
  • catabolism ?? anabolism
  • Catabolism break down
  • (digest food into protein)
  • Anabolism build up
  • (rearrange proteins into new cells)

17
CELLS
  • Functional structural building block of life
  • This makes them the
  • SMALLEST LIVING THINGS!

18
CELLS HAVE 3 THINGS IN ALL COMMON
  • Made of Cytoplasm Nucleus enclosed by a Cell
    Membrane
  • Cytoplasm fluid in a cell
  • Nucleus cells control center, brain
  • Cell Membrane outermost part of a cell,
  • the cells skin

19
The Order of Perspectives on Human Biology (HB)
  • 1 Atoms
  • 2
    Molecules
  • 3
    Organelles
  • 4 Cells
  • 5 Tissues
  • 6 Organs
  • 7 Organ
    systems
  • 8
    OrganismsYOU!
  • 9
    Populations
  • 10
    Ecosystem
  • 11
    Biosphere

small
big
20
The Order of Perspectives on Human Biology (HB)
  • 1 Atoms
  • 2
    Molecules
  • 3
    Organelles
  • ---------------------------- 4 Cells
    -----------------------------------
  • 5 Tissues
  • 6 Organs
  • 7 Organ
    systems
  • 8
    OrganismsYOU!
  • 9
    Populations
  • 10
    Ecosystem
  • 11
    Biosphere

NOT ALIVE!
ITS VERY ALIVE!
21
HUMAN BIOLOGY IS EVERYWHERE!
  • Internet
  • Magazines
  • TV News
  • Newspapers
  • Books

22
HUMAN BIOLOGY IS EVERDAY INVOLVING EVERYONE!
  • Cloning
  • Human Genome Project (HUGO)
  • Curing AIDS
  • Saving the rainforest
  • Genetic engineering to cure genetic diseases
  • EX- MS, CF, Dyslexia, Diabetes, Some cancers

23
HUMAN BIOLOGY IS EVERBODY!
  • In 1999, world population exceeded 6 billion!
  • Not enough space, food, energy, resources for
    everyone is a very SERIOUS problem.

24
RAINFORESTS HUMANS
  • Destroying rainforests to make space to live
    affects plants animals
  • Half of the worlds species live in the
    rainforests
  • Tropical rainforests are currently being
    destroyed at a rate greater than 1 acre/ second!
  • At this rate, the last tree will fall by 2050!

25
RAINFORESTS HUMANS
  • This will destroy over 1 million species, making
    it the greatest extinction since the dinosaurs of
    65 million years ago!
  • Who knows what potential medicines, foods,
    plastics, and genetic material we are losing?
  • Biologists seek balance between the need for land
    protecting ALL life.

26
MORE PEOPLE MEANS MORE FOOD IS NEEDED
  • Biologists seek new crops to grow more
    efficiently in tropical soils without too much
    fertilizer or pesticides
  • Genetic engineers place plant genes into other
    plants to form new crops that are germs insect
    resistant AND bear fruit many times a year!
  • EX- New crops are frost resistant due to inserted
    genes
  • Insect resistant crops decrease the amount of
    bug spray used (saves )

27
HUMAN BIOLOGISTS SEEK CURES
  • AIDS
  • Cancer
  • CF (cystic fibrosis)
  • MS (multiple sclerosis)
  • MD (muscular dystrophy)
  • Diabetes
  • Heart Problems (cardiopathies)
  • Many others

28
AIDS
  • Acquired Immunodeficiency Syndrome
  • Since 1981 (when 1st recognized) 50 million
    people have been infected
  • 14 million already dead, 2 million die per year
  • Caused by HIV Human Immunodeficiency Virus
  • It is an STD, also spread by other body fluids
  • NOT including urine (pee) , feces (poop) sweat.

29
HUMAN BIOLOGISTS SEEK CURES
  • Yes, AIDS-like diseases also affect other animals
  • FIV Feline Immunodeficiency Virus
  • FIV ONLY affects cats
  • It is highly contagious among cats
  • FIV is curable
  • Humans do not catch it.
  • Some forms of HIV can spread to other primates
    (chimps, monkeys, bonobos, etc.)

30
CANCER
  • Cellular growth disorder
  • When cells do not know when to stop reproducing
  • Can be prematurely set off by chemicals
  • (esp. in tobacco)
  • Many human cancers are know curable, thanks to
    HUGO (HUman GenOme project)
  • We will see this in detail in later chapters

31
CF
  • Cystic Fibrosis
  • Fatal disorder in which abnormally thick mucus
    builds up in many organs, esp. the lungs
  • Too much mucus, not enough breathing
  • Caused by a defective gene
  • Researchers try to treat fatal CF with
  • GENE THERAPY

32
GENE THERAPY
  • Gene therapy replacing a defective genes with a
    healthy, normal one
  • This treatment is used by GENETIC ENGINEERS
    sometimes called GENE THERAPISTS.
  • This treatment may 1 day cure most genetic
    diseases, like CF, MS, MD, diabetes, dyslexia.
  • The difficulty is not finding healthy genes, but
    introducing the normal genes into defective DNA.

33
1-2 REVIEW
  • 1 Human Biology is a large part of everday life
  • 2 Addressing a growing human population,
    environmental damage, human disease demand an
    answer we are gradually finding.

34
HOW IS HUMAN BIOLOGY STUDIED?
  • Scientific Method
  • 1 Observation --- using the 5 senses
  • 2 Hypothesis---educated guess
  • 3 Prediction that is falsifiable (can be proven
    wrong)
  • Test (Experiment)
  • Conclusion

35
OBSERVATION
  • Native American peoples today have smaller teeth
    than the skulls of the same peoples 2000 years
    ago.

36
HYPOTHESIS
  • Native American peoples needed larger teeth to
    eat grains and unprocessed foods before industry
    entered the USA and made other foods easier to
    obtain.

37
PREDICTION
  • IF the hypothesis is TRUE
  • Comparing teeth measurements on the skulls of
    ancient Shawnees to those of modern Shawnees on
    OK reservations will prove that the modern teeth
    are smaller.
  • IF the hypothesis is NOT TRUE

38
TEST
  • Perform an EXPERIMENT
  • Experiment test to prove or disprove a
    hypothesis
  • Apply the comparative method to the Sioux,
    Iroquois, or Chickasaw Tribes.
  • Ask Why are the Shawnee different? if they
    prove to differ in teeth size compared to other
    tribes.
  • Research Shawnee diet and eating habits.

39
CONCLUSION
  • Evidence from the experiment either does or does
    not support the hypothesis.
  • In the comparative teeth experiment
  • The evidence actually does support the
    hypothesis.
  • From this we could form a CONCLUSIVE STATEMENT

40
CONCLUSIVE STATEMENT
  • Comparing teeth size in 2000 year old Shawnees to
    the modern day Shawnee proves that Shawnee teeth
    have gotten smaller.

41
Example of the Scientific Method
  • Observation Eating red grapes induces labor in
    rats
  • Hypothesis Caused by an agent in red grapes
  • Prediction If the hypothesis is true, then
    pregnant rats given red grape juice (experimental
    treatment) will go into labor before rats given
    white grape juice (control treatment) go into
    labor.
  • Test Do the experiment
  • Conclusion Based on the results of the experiment

42
THEORY LAW
  • THEORY explanation based on a set of related
    hypotheses that have been tested confirmed many
    times
  • EX- Theory of Evolution
  • LAW theory or a set of theories generally
    accepted as scientifically true accurate
  • Some theories are so strongly supported that
    likelihood of their being rejected in the future
    is small
  • EX Law of Gravity

43
SCIENTIFIC TRUTH
  • SCIENTIFIC TRUTH
  • There is no absolute certainty in a
    scientific theory. The possibility always
    remains that future evidence will cause a
    scientific theory to be revised or rejected. A
    scientists acceptance of a theory is always
    provisional.
  • EC- Define FAITH

44
ATOMS
  • Smallest units of matter
  • Cannot be broken down further by chemical means
  • Made of 3 subatomic particles
  • 1 Proton
  • 2 Electron
  • 3 Neutron

45
SUBATOMIC CHART
  • Neutrons Protons
    Electrons
  • Mass 1 1
    0
  • Charge 0 1
    -1
  • Symbol nº p
    e-

46
SUBATOMIC MASS CHARGE
  • Subatomic mass is measured in a unit called amu
  • amu stands for atomic mass unit
  • 1 amu the mass of 1 p
  • 1 amu 1/1,660,600,000,000,000,000,000,000 gram
  • Roughly 1.7 septillionth of a paper clips mass!
  • The 1 charge of the p and the 1 charge of the
    e-
  • are relative charges. Theres no actual unit
    (like volt)
  • Actual charges 1.67x10 -19 coulombs (C) for p
  • -1.67x10 -19
    coulombs for e-

47
NUCLEUS
  • Nucleus center of the atom
  • Always has p
  • Thus it always has an overall charge.
  • Sometimes it contains neutrons (NO charge)

48
ORBITALS
  • A cloud or haze of orbiting e- around the
    nucleus
  • AKA Energy levels, energy shells,
  • e- levels, or e- shells
  • Electrons ALWAYS orbit the nucleus
  • Electrons are NEVER found inside the nucleus

49
ALL ATOMS ARE ELECTRICALLY BALANCED (electrically
neutral)
  • There is ALWAYS 1 e- for every p
  • Thus
  • p e-
  • EX-
  • 2 p 2 e- 0
    (electrically neutral)

50
ELEMENTS
  • Defined as a pure substance of only 1 type of
    atom
  • There are currently 114 known elements
  • Make up the Periodic Table of the Elements
  • They differ in their number of protons (p)
  • ATOMIC NUMBER number of protons (p)
  • Atomic p

51
ATOMIC NUMBER
  • Atomic p
  • EX- Hydrogen has 1 p, Helium has 2 p
  • Thus 1H and 2He
  • H has the atomic 1, He has the atomic 2

52
ELEMENTS IN THE HUMAN BODY
  • There are about 20
  • Most common are
  • Element Atomic
  • Carbon (C) 6
  • Hydrogen (H) 1
  • Oxygen (O) 8
  • Nitrogen (N) 7
  • Phosphorus (P) 15

53
ATOMIC WEIGHT (or mass)
  • Atomic weight (mass) refers to the weight (mass)
    of the nucleus or the mass of all those p and
  • Atomic weight p nº
  • RECALL the nucleus is made of p and nº
  • p and nº each weigh 1 amu (atomic mass unit)
  • Adding a p adds BOTH 1 amu and 1 C to the
    nucleus.
  • Adding a nº adds ONLY 1 amu. There is no extra
    charge added (after all neutrons are neutral, O
    C)
  • So.

54
ATOMIC WEIGHT (or mass)
  • Atomic weight p nº
  • More p means more charge
  • More nº just means it weighs more
  • Neutrons are atomic fat!!
  • They just add weight and nothing else.

55
ELEMENTS IN THE HUMAN BODY
  • There are about 20
  • Most common are
  • Element Atomic
    Atomic Weight
  • Carbon (C) 6
    12
  • Hydrogen (H) 1
    1
  • Oxygen (O) 8
    16
  • Nitrogen (N) 7
    14
  • Phosphorus (P) 15
    31
  • Atomic weight p nº

56
ATOMIC DATA
  • How to quickly find
  • p atomic number
  • e- atomic number also
  • RECALLall atoms are balanced so p e-
  • nº atomic weight atomic number nº
  • (p nº) -- p
  • EX- (2 3) -- 2
    3nº

57
ISOTOPES
  • Isotope An element that does not have the
    typical
  • number of neutrons
  • EX- Natural carbon is 12C.
  • 11C, 13C, and 14C are isotopes (as in 14C
    dating)
  • (sometimes less nº, sometimes more nº)
  • Often unstable causing the nucleus to
    disintegrate
  • This causes the emission of high energy particles
    (like X rays) known as RADIATION.

58
MOLECULES COMPOUNDS
  • Molecule Group of atoms chemically joined
  • Compound substance made of more than 1 kind of
    element
  • EX- 2 oxygen atoms ?1 oxygen gas molecule
  • (OO) ? (O2)
  • 2 hydrogen atoms 1 oxygen atom ? H2O (water)
  • Water is BOTH a molecule a compound.

59
3 KINDS OF CHEMICAL BONDS
  • 1 Ionic steals e- (attraction of /-)
  • 2 Covalent shares e-
  • 3 Hydrogen polarity

60
IONIC BONDS
  • Steals e- to form IONS that attract each other
  • ION atom with an overall /- charge
  • Cation ions
  • Anion -- ions
  • EX- Na attracts Cl- to form NaCl.table salt
  • NaCl is an example of an IONIC
    compound

61
COVALENT BONDS
  • Covalent bonds form when atoms share e-
  • EX- Carbon shares e- with 4 hydrogen atoms
  • H
  • This is
    CH4 (methane)
  • H--- C ---H
  • H

62
HYDROGEN BONDING
  • Weakest bond, occurs between POLAR molecules
  • Polar molecules have 1 end and 1 end, sort of
    like a bar magnet or a AA battery.
  • They can bond to themselves in chains.
  • EX-
  • -- --
    --

63
WATER IS POLAR!
  • Water bonds to itself in chains
  • H H H
    H
  • O- O- O-
    O-
  • H H H
    H

64
WHY IS WATER WET?(yes, there really is a reason
why!)
  • Because it is both ADHESIVE COHESIVE!
  • Cohesive it bonds to itself (in drops)
  • Adhesive it bonds to other things (like glass)
  • H H H
    H
  • O- O- O-
    O-
  • H H H
    H

65
Review the 3 Kinds of Chemical Bonds
  • 1 Ionic- By gaining or losing e-, ions of
    opposite charges are attracted to each other
  • 2 Covalent- atoms sharing e-
  • 3 Hydrogen- weak bond between the oppositely
    charged poles (ends) of polar molecules

66
PREDICTING CHEMICAL BONDS
  • Which chemicals will bond and which bond they
    form is not by chance.
  • It depends on the of e- needed to complete the
    outermost electron orbital.
  • VALENCE electrons the outermost electrons
  • This is the basic idea of the Octet Rule

67
THE OCTET RULE
  • Oct- 8
  • A) Inner orbitals MUST fill first
  • B) 1st orbital holds 2 e- max
  • C) 2nd orbital holds 8 e- max
  • D) 3rd orbital holds 8 e- max

68
WHAT DETERMINES IF AN ATOM IS BALANCED OR STABLE?
  • By using the term ATOM, we mean it is BALANCED or
    ELECTRICALLY NEUTRAL
  • BALANCED means the p e-
  • All ()s plus all (-)s 0, they cancel each
    other out
  • STABLE means the chemicals will not REACT
    (will not try to form any type of bond).
  • STABLE they have a FULL VALENCE

69
INERT GASES
  • Inert not active, will not react
  • Have a completed outer (valence) e- orbital is
    stable
  • Last column on right in Periodic Table of
    Elements
  • AKA Noble Gases

70
INERT GASES (He)
  • Helium (He) atomic 2
  • 2 p and 2 e-
  • 2 e- in inner orbital, He is chemically
    non-reactive

71
INERT GASES (Ne)
  • Neon (Ne) atomic 10
  • 2 e- in inner orbital, 8 e- in 2nd orbital
  • Ne is chemically non-reactive

72
IONS
  • An ion is an atom (or group of atoms) that
    carries an electric charge (/-)
  • Formed by too many or too little e-
  • Cation ion
  • Anion -- ion
  • EX- Na, Cl- , NH4 , C2H3O2-

73
SODIUM CATION
  • Sodium atomic 11
  • 11 p and 11 e-
  • 2 e- in 1st orbital, 8 e- in 2nd orbital 1 e-
    extra
  • The extra e- is lost (stolen), leaving the sodium
    cation with a net positive chargeNa

74
CHLORINE ANION
  • Chlorine atomic 17
  • 17 p and 17 e-
  • 2 e- in 1st orbital, 8 e- in 2nd orbital, 7 e-
    extra
  • 7 extra e- fill the 3rd orbital
  • It needs 1 more e- to be chemically stable
  • Chlorine anion attracts an extra e- to complete
    its valence orbital ? has a net negative charge
    (Cl-)

75
OPPOSITES ATTRACT
  • and charged ions attract each other
  • Na joins Cl- to become NaCl (table salt)
  • The molecule is both BALANCED STABLE.
  • This is an IONIC BOND
  • The bond comes from the mutual attraction of
    oppositely charged ions
  • e- pass from 1 ion to another
  • They are NOT shared, more like STOLEN!

76
COVALENT BONDS
  • When e- are shared between atoms
  • HYDROGEN
  • Hydrogen atomic 1
  • 1p and 1 e-
  • Needs 1 more e- to complete 1st orbital

77
COVALENT BONDS
  • CARBON
  • Carbon atomic 6
  • 6 p and 6 e-
  • 6 e- is enough to fill the 1st orbital (2 e-)
    with 4 e- left over for the 2nd orbital
  • It needs 4 more e- to complete it valence.

78
COVALENT SINGLE BONDS
  • When 1 e- is shared, shown by 1 line
  • 1 carbon shares its valent e- with 4 hydrogens
  • H
  • This is
    CH4 (methane)
  • H--- C ---H
  • H

79
COVALENT BONDS
  • OXYGEN
  • Oxygen atomic 8
  • 8p and 8 e-
  • Inner orbital filled with 2 e-
  • 6 e- left over for 2nd orbital
  • It needs 2 more e- to complete the 2nd orbital

80
DOUBLE COVALENT BONDS
  • When 2 pairs of electrons are shared
  • Shown by 2 lines ()
  • EX- OCOCO2.Carbon dioxide
  • OO.O2Diatomic oxygen
  • HONO.HNO3.Nitric acid
  • H
  • Diatomic 2 alike atoms bonded together (N2 ,O2,
    H2)

81
HYDROGEN BONDS
  • Relatively weak bond between a positively charged
  • hydrogen ion (H) in a molecule and a
    negatively charged ion in another
    molecule
  • EX- RECALL, polar water forms cohesive chains.
  • HH
  • O negative O end attracted by positive
    H end
  • HH
  • O

82
POLAR MOLECULES
  • Polar molecules molecules with an unequal
    distribution of electrical charge (more e- on 1
    end)
  • EX- water, isopropyl alcohol, hydrogen peroxide

83
NONPOLAR MOLECULES
  • Nonpolar molecules- molecules that have an equal
    distribution of electrical charges (e-)
  • EX- gasoline, oil, wax, fatty acids

84
RATING THE STRENGTHS OF CHEMICALS BONDS
  • GOLD--------Covalent
  • SILVER-------Ionic
  • BRONZE-----Hydrogen

85
REVIEW
  • All matter is made of atoms
  • Atoms consist of e-, p, nº
  • Molecule group of atoms bound by covalent bonds
  • H bonding occurs between polar molecules
  • Ion atom with a charge
  • Opposites charges may form ionic bonds
  • Sec 2-1 Q1-5 pg 30

86
WHAT IS pH?
  • Water has 2 ions
  • H plus OH- H2O
  • H cation is a positive hydrogen ion
  • OH- anion is called a hydroxide or hydroxyl group
  • pH is a way of counting those H cations

87
POTENZ H
  • The H in pH stands for H (or hydrogen cation)
  • The p in pH stands for potenz
  • Potenz is the German term for
  • the negative power of H
  • When H increases, OH- decreases
  • Its a fraction!
  • H x OH- 10-14 or 1/100,000,000,000,000

88
THE pH SCALE
  • Think of pH as asking
  • How many H are in a solution?
  • The pH scale refers to H only
  • The pH scale runs from 0-14
  • lt7 acid, more H
  • 7 neutral, like water because it has both H
    OH-
  • gt7 base or alkaline, less H

89
THE pH SCALE
  • 0---------------------------7-----------------
    -----------14
  • Acid Base
  • H, OH-
    H, OH-
  • Neutral
  • (H2O or HOH)
  • H OH-

90
THE pH SCALE

91
The pH UNIT
  • Each pH unit represents a factor of 10
  • EX-
  • The pH 6 is 100x more acidic than the pH 8
  • (8-6 2102 100)
  • Try thisItem A pH 9, Item B pH 5
  • Which Item is more acidic and by how much?

92
pH IN THE HUMAN BODY
  • The body must maintain the pH of stuff within a
    narrow range limits for the normal functioning of
    physiological processes
  • Blood pH.7.2-7.4
  • Saliva (spit) pH7
  • Cytoplasm.7.2
  • Stomach juices pH2
  • Lysosome pH4-5
  • Small intestine pH.8
  • cells digestive enzyme sac--digests glucose
    (1 human fuel)

93
WATER
  • Covers 75 of the planet Earth
  • Is molecularly 67 of the human body
  • Polar ions dissolve well in it, after all
  • Water is the UNIVERSAL SOLVENT, because most
    things will dissolve in it.
  • Has a high heat of evaporation ? heat constancy
  • Water is not lost easily body temp. remains
    stable

94
OTHER MOLECULES
  • Other molecules are much, much bigger than water
  • EX- proteins, carbohydrates, lipids, DNA
  • These are ORGANIC molecules
  • they all contain carbon (C)
  • Sec 2-2 Q1-5 pg 33

95
ORGANIC MOLECULES
  • Always contain carbon (C)
  • NO C, NO LIFE! All life on Earth is C based
  • Cs 4 bonding sites allow life to be possible.
  • Life on other planets SHOULD also be C based.
  • If not, they may be silicon (Si) based as it too
    has 4 bonding sites.
  • Note the location of C and Si on the Periodic
    Table.

96
ORGANIC MOLECULES
  • Always contain carbon (C )
  • Usually also contain hydrogen (H), oxygen (O),
    /or nitrogen (N)
  • C and others are usually in long covalent chains
  • EX- carbohydrates, proteins, lipids, enzymes,
  • nucleic acids

97
CARBOHYDRATES
  • Ratio of CHO 121
  • EX- C1H2O1 or C3H6O3
  • Often abbreviated as CHO
  • May exist as single molecules or in complex
    chains

98
MONOSACCHARIDES
  • Simple sugars
  • Mono 1, saccharide sugar
  • Sugar names end in ose
  • Glucose- C6H12O6---the basic plant sugar
  • Fructose- in fruits like pears, pineapples
  • Galactose- in plants and milk

99
MONOSACCHARIDES

100
DISACCHARIDES
  • Are double sugars
  • Di- means 2
  • Monosaccharides monosaccharides disaccharide
  • Sucrose some fruits
  • Lactose in milk
  • Maltose in (malt) chocolate

101
DISACCHARIDES

102
POLYSACCHARIDES
  • Polysaccharides are CHOs that exist as long
    chains of monosaccharides.
  • Poly- many
  • EX- Starch- in potatoes
  • Glycogen-stored body energy (not exactly fat
    close)
  • Cellulose- pulpy stuff from plants makes paper
  • Chitin (KI ten)- hard fiber found in animal
    shells, insect exoskeletons (shells) in the
    cell walls of fungi (mold mildew)

103
POLYSACCHARIDES

104
CHO COMPLEXITY
  • CHOs are divided into 2 groups
  • Simple CHOs Complex CHOs
  • Simple CHOs include both monosaccharides and
  • disaccharides
  • Complex CHOs include polysaccharides

105
SIMPLE CHOs
  • Covalent bonds hold ALL monosaccharides together
  • Glucose is the most important simple CHO!
  • Glucose (C6H12O6) is the primary fuel for humans!
  • (its the only fuel source used by the brain!)
  • Glucose is made by plants during photosynthesis
  • Glucose is made of 6 C molecules that form a ring
    when they are dissolved in water.

106
EXAMPLES OF SIMPLE CHOs
  • Mono- Mono- Di-
  • glucose fructose SUCROSE
  • glucose glucose MALTOSE
  • glucose galactose LACTOSE

107
COMPLEX CHOs
  • These are polysaccharides long chains of
    monosaccharides joined by covalent bonds
  • They serve as stored energy in plants (starch)
  • animals (glycogen)
  • Humans store glycogen in the liver muscles
  • May be converted back into glucose when energy is
    needed

108
COMPLEX CHOs
  • Some polysaccharides are rigid structural
    materials
  • EX- Cellulose in plants, Chitin in arthropod
    shells
  • Mammals cannot free glucose from cellulose alone
  • We need help from bacteria in the post-stomach
    digestive tract to break down cellulose fibers
  • Cellulose fibers are what we call roughage
  • It is truly rough to digestlike the strings in
    celery

109
REVIEW
  • pH scale 0-14, 0 acid (H), 14 base (OH-)
  • 7 neutral (H2O or HOH) has both H OH-
  • No C, No water, NO LIFE!
  • C,H,O,N make organic molecules long chains
  • Mono-, disaccharides are simple CHOs
  • Polysaccharides are complex CHOs
  • CHOs give people energy
  • Glucose is the primary human fuel

110
LIPIDS
  • Type of fat
  • These are non-polar molecules
  • Nonpolarequal distribution of electrical charge
    (e-)

111
NONPOLAR REPELS WATER
  • Nonpolar molecules never dissolve in water
  • EX- water will not dissolve oil, gas, or wax
  • Hydrophobic-(fears water) wont dissolve in H2O
  • Hydrophilic- (loves water) easily dissolves in
    H2O

112
LAW OF POLARITY
  • Like dissolves in like
  • Polar dissolves in polar ONLY
  • Nonpolar dissolves in nonpolar ONLY
  • Water and oil dont mix!

113
3 TYPES OF LIPIDS ESSENTIAL TO HUMANS
  • 1 Triglycerides
  • 2 Phospholipids
  • 3 Steroids

114
TRIGLYCERIDES
  • Made of a Glycerol head and 3 Fatty Acid tails
  • May be saturated or unsaturated

115
SATURATED FATTY ACIDS
  • The saturated fatty acid tails are C chains
    crammed full or saturated with hydrogen atoms .
  • Saturated fats (EX-butter) are solid at room
    temp.
  • Too much is VERY unhealthy!

116
UNSATURATED FATTY ACIDS
  • A double covalent bond exists between at least 1
    pair of Cs (where Hs could bond with the C)
  • CC
  • Unsaturated fats (EX-olive oil) -liquid at room
    temp.
  • MUCH healthier (hydrogenated vegetable oil)

117
POLYUNSATURATED FATTY ACIDS
  • Unsaturated fats with fatty acid chains
    containing more than 1 double covalent bond
  • Poly- manyEX- CCCC
  • Healthiest of all!

118
PHOSPHOLIPIDS
  • Glycerol head,2 fatty acids phosphate group
    (PO4)
  • Glycerol fatty acids are nonpolar (hydrophobic)
  • Phosphate groups are polar (hydrophilic)
  • A cell membrane (cells skin) is made of a double
    layer of phospholipids phospholipid bilayer

119
STEROIDS
  • 4 C rings a functional group ( R)
  • Many different kinds
  • Important in reproductive maturation metabolism
  • EX- Estrogen, testosterone, cholesterol
  • NO FAT, NO SEX!

120
PROTEINS
  • PROTEINS chains of AMINO ACIDS (AA)
  • Proteins are the building blocks of most body
    structures (hair, cells, muscle, bone)
  • Most common organic molecule..its even in comets
  • Found in ALL life.

121
AMINO ACIDS
  • Chainlike molecules with a central C bonded to
  • 1 Amino group (NH2)
  • 2 Carboxyl group (COOH)
  • 3 a single hydrogen atom (H)
  • 4 Side functional group (R )

122
THE AMINO ALPHABET
  • There are 20 amino acids important to biology
  • There are 26 letters in the English alphabet
  • Like how the order and amount of letters used
    determine which word made, so the order and
    amount of AA used determine which protein is
    made.
  • What words are made from T,C,A?

123
NUCLEIC ACIDS
  • Nucleic acids Long chains of smaller
    molecules called NUCLEOTIDES
  • Nucleotides have 3 parts
  • 1 sugar (-ose)
  • 2 base (OH-, the opposite of an acid)
  • 3 phosphate group (PO4)

124
2 TYPES OF NUCLEIC ACIDS
  • 1 DNA (deoxyribonucleic acid)
  • 2 RNA (ribonucleic acid)

125
DNA
  • DNA has 2 strands of nucleotides that spiral
    around each other.
  • This is called a double helix
  • Shape was discovered by Watson Crick in 1953
  • The strands are held together by H bonds between
    bases across from each other forming the
    rungs of the twisted ladder.

126
CHROMOSOMES ARE DNA
  • Chromosomes are made up of very long strands of
    DNA, which is the code on genes containing the
    instructions for making proteins

127
RNA
  • Single strand of nucleotides
  • Plays several roles in cells, esp. in making
    protein

128
ATP
  • ATP a nucleotide called adenosine triphosphate
  • Its a single nucleotide with 2 extra, high
  • energy-storing phosphate (PO4) groups
  • It stores energy ONLY TEMPORARILY, like a
    battery, between the 2nd 3rd PO4s.
  • A-PO4-PO4 PO4
  • When we catabolize food, energy is released.
  • Energy is captured stored in ATP,
    later used to operate the bodys
    individual cells.

129
REVIEW
  • Organic componds (C) are found in living things.
  • CHOs, like glucose, are energy sources some are
    used as structural materials in organisms.
  • Lipids are nonpolar molecules that store energy
    found in cell membranes as phosphlipids.
  • Proteins are chains of AA, The AA sequence
    determines a proteins shape function.
  • Nucleic acids store transmit heredity info.
  • ATP is the main energy currency of cells
  • Sec 2-3 Q 1-5 pg 37

130
WHAT GOOD ARE PROTEINS?
  • ENZYME BOOK CH 2-4?

131
CYTOLOGY
  • Cyte- cell
  • -ology study of
  • CYTOLOGY study of cells

132
FOUNDERS OF CYTOLOGY
  • Robert Hooke
  • Anton van Leeuwenhoek
  • Mattias Schleiden
  • Theodor Schwann
  • Rudolph Virchow

133
ROBERT HOOKE
  • In 1665 observed slices of cork under a
    microscope
  • He saw little boxes
  • He named these boxes cells, because they
    reminded him of the small rooms where monks
    lived inside monastaries.

134
ANTON van LEEUWENHOEK
  • Used a microscope to observe drops of rain water
  • He discovered little creatures living there!
  • He named these creatures animalcules, which
    means tiny animals.

135
INTERNATIONAL SYSTEM OF MEASUREMENTS
  • Abbreviated SI
  • Same thing as the metric system
  • It is a decimal system
  • All units are based upon powers of 10
  • WHY?

136
BRIEF SI TABLE
  • Meter base unit for measuring distance
  • Meter literally means measure________________
  • kilo- 1,000
  • -meter 1
  • centi- .01 or 1/100
  • milli- .001 or 1/1000
  • micro- .000001 or 1/1,000,000 (1 millionth)
  • nano- .000000001 or 1/1,000,000,000 (1
    billionth)

137
SI SYMBOLS
  • km kilometer
  • meter 3.???ft
  • cm centimeter
  • mm millimeter
  • µm micrometer
  • nm nanometer

138
CHARACTERISTICS OF MICROSCOPES
  • Two Types of Microscopes
  • 1 Light microscopes
  • 2 Electron microscopes

139
LIGHT MICROSCOPES
  • Light passes through one or more lenses to
    produce an enlarged image of a specimen or
    MICROGRAPH
  • MICROGRAPH an image produced by a microscope

140
MAGNIFICATION
  • Ability to make an image appear larger than its
    actual size
  • EX- Magnification value of 200x means the image
    is 200 times larger than the actual specimen

141
RESOLUTION
  • A measure of the clarity of an image
  • RECALLAs magnification increases,
  • resolution decreases!
  • The bigger the image, the blurrier it
    gets!

142
ELECTRON MICROSCOPES
  • Forms an image of a specimen using a beam of
    electrons instead of light
  • No cell can survive an e- microscope as specimen
    preparation requires a type of staining being
    placed in a vacuum (/or being sliced!)
  • TWO TYPES
  • 1 TEM transmission e- microscope
  • 2 SEM scanning e- microscope

143
TEM
  • Transmission e- microscope
  • The e- beam is aimed at a slice of a specimen
    stained with metal ions
  • TEM micrographs are always black white

144
SEM
  • Scanning e- microscope
  • The e- beam is aimed at a specimen coated with
    metal ions
  • SEM micrographs are 3D, usually BW, but can be
    artificially colored

145
STM
  • Scanning Tunneling Microscope
  • Uses a needle-like probe to measure differences
    in voltage caused by e- s that leak,or tunnel,
  • from the surface of a specimen
  • A computer tracks the movement of the probe
  • STM micrographs are 3D and in color
  • STMs can be used to study living specimens
  • You can even see individual atoms!

146
MICROSCOPE REVIEW
  • Microscopes enable us to examine the details of
    cell structure to understand how organisms
    function.
  • Scientists use the SI system to measure the size
    of objects
  • Light microscopes have a low magnification can
    be used to examine living cells.
  • Electron microscopes have a high magnification,
    but cannot be used to study living cells
  • The STM uses a computer to generate 3D images of
    a specimen.
  • Sec 3-1 Q1-5 pg 54

147
CELL THEORISTS
  • Mattias Schleiden--
  • German botanist in 1838 concluded that a plant
    was composed entirely of cells
  • Theodor Schwann--
  • German zoologist who claimed that animals were
    also made up of cells
  • Rudolph Virchow--
  • German physician who determined that cells come
    only from other cells

148
CELL THEORY
  • Based on the combined observations of
  • Schleiden, Schwann, Virchow
  • All living things are made of one or more cells
  • Cells are the basic unit of structure function
  • All cells arise from pre-existing cells

149
CELLS MUST BE SMALL
  • Small cells work more efficiently than large
    cells
  • All substances that enter or leave a cell must
    cross the cells surface
  • If the cells surface-to-area ratio is too low,
    substances cannot move through the cell quickly
    enough to meet the cells needs.
  • Substances do not need to travel as far to reach
    the center of a smaller cell.
  • This is why smaller things are more efficient
    (ants).

150
CELL FEATURES
  • There are many parts needed to make up a
    functioning cell.
  • These parts are referred to as cellular
    features or organelles (meaning little
    organs)

151
CELL MEMBRANE
  • Outer boundary, skin
  • Encloses the cell separates its interior from
    its outer surroundings
  • Regulates what enters leaves the cell

152
CYTOPLASM
  • Is the interior of a cell
  • It is mostly water, so it is very fluid

153
CYTOSKELETON
  • A collection of connected microscopic protein
    fibers that suspends other cell structures within
    the cytoplasm
  • Like the metal skeleton of a skyscraper,
  • only much smaller.
  • The cytoskeleton holds the cell together keeps
    it from collapsing

154
RIBOSOMES
  • Cellular structures that make protein
  • These are the Protein Factories!

155
DNA
  • Deoxyribonucleic acid
  • Provides the instructions for making protein that
    will be read by the ribosomes.
  • These instructions regulate cell activity and
    provide a raw building material for making what
    the cell needs.
  • It also enables the cell to reproduce by storing
    hereditary information.

156
TWO TYPES OF CELLS
  • 1 Prokaryotes
  • 2 Eukaryotes

157
PROKARYOTES
  • Simplest smallest cells
  • Lack a nucleus other internal compartments
    known as organelles.
  • Cannot carry out specialized functions
  • Genetic material is a single circular strand of
    DNA
  • Modern prokaryotes are called BACTERIA

158
BACTERIA
  • Modern prokaryotes
  • Exist in a broad range of conditions
  • Grow divide rapidly
  • Some can make their own food
  • Some can live without oxygen
  • Enzymes ribosomes are free to move around in
    the cytoplasm because there are no internal
    structures (organelles) to divide the cell into
    compartments their parts float around in
    there!
  • DNA is circular (ring), suspended in the cytoplasm

159
CELL WALL
  • Surrounds the cell membrane to provide
  • protection, structure, support.
  • Think of the cell membrane as the SKIN,
  • The cell wall as the SUIT OF ARMOR.
  • Cell walls are found in bacteria, fungi,
    plants.

160
CAPSULE
  • Strands of polysaccharides that may surround the
    cell wall of a bacteria
  • These enable the bacteria to cling to almost
    anything
  • The capsule is like a Velcro suit!

161
FLAGELLA
  • Single (only 1) called a flagellum
  • More than one called flagella
  • Long, threadlike structures that protrude from
    the cells surface
  • Long, whip-like tails that allow some cells to
    swim or move

162
EUKARYOTES
  • First cells with internal compartments
  • Have a nucleus
  • Have other organelles

163
NUCLEUS
  • Control center of the cell, like the brain
  • Internal compartment (organelle) that
  • houses the cells DNA
  • It has all the info. (DNA), so it is the
  • boss (control center)!

164
ORGANELLE
  • Any structure that carries out a specific
    activity inside of a cell
  • It comes from the French language meaning
  • little organs. (-elle little)

165
CILIA
  • Small hair-like structures, found on some
    eukaryotes, that protrude from the cell membrane.
  • Used to make oar-like movements
  • May be used to help a cell swim through a fluid
  • May also be used to move substances across a
    cells surface
  • EX- Cilia in the wind pipes sweep debris mucus
    out of the lungs

166
CYTOPLASM vs. PROTOPLASM
  • Cytoplasm everything inside the cell membrane,
  • BUT OUTSIDE the nucleus
  • Protoplasm Everything inside the cell membrane,
    including the nucleus
  • Protoplasm is ALLDAT, cytoplasm is not.
  • EX- Cytoplasm Nucleus Protoplasm

167
CYTOSKELETON FIBERS
  • The eukaryotic cell is supported by the
    cytoskeleton
  • There are 2 types of protein fibers that form the
    cytoskeleton
  • 1 Microtubuleshollow, flexible
  • 2 Microfilamentssolid, rigid

168
MICROTUBULES
  • 1 of the 2 types of protein fibers in the
    cytoskeleton
  • Microtubules are long tubes (tubules)
  • Long, hollow tubes that extend throughout
    the cytoplasm
  • These, being hollow, are easy to bend and allow
    the cell to flex and it may also help move
    organelles around inside the cell

169
MICROFILAMENTS
  • 1 of the 2 types of protein fibers in the
    cytoskeleton
  • These are thin protein strands that help support
    the cells shape structure
  • They are solid, unlike microtubules.
  • These give strength and rigidity to the
    cytoskeleton
  • Microfilaments hold things in place, restricting
    movement

170
CELL STRUCTURE REVIEW
  • Cell membrane Skin
  • Cell wall Suit of Armor
  • Capsule Velcro Suit
  • Nucleus Brain
  • Flagella long swimming tail, whip-like
  • Cilia short swimming hairs, oar-like
  • Cytoskeleton 2 protein fibers
  • 1 microtubules (hollow), 2 microfilament (solid)

171
CELL MEMBRANES
  • Cell membranes are fluid like a soap bubble.
  • The fluidity of the cell membrane is caused by
    lipids
  • These lipids form a barrier that separates the
    inside of a cell from the outer environment
  • The cell membrane is selectively permeable
  • It allows only certain substances to enter and
    exit
  • the cell

172
PHOSPHOLIPIDS
  • Interacts with water to cause a cell membrane to
    become selectively permeable
  • Made of a phosphate group (PO4) with 2 fatty
    acids
  • Has a polar head and 2 nonpolar tails
  • The head contains the phosphate group is
    attracted to water (hydrophilic loves water)
  • The tails contain the nonpolar fatty acids
  • repels water (hydrophobic fears water)

173
LIPID BILAYER
  • Phospholipids arranged in double layers (2 ply)
  • This arrangement is found in the cell membrane
  • Nonpolar tails of the phospholipids make up the
    interior of the bilayer they are forced to
    remain here because water inside outside the
    cell repels them.
  • Ions polar molecules, including proteins
    sugars, are repelled by the nonpolar interior of
    the bilayer, forcing them to remain outside the
    cell.
  • It takes an active door to let them inside the
    cell.

174
PROTEINS EMBEDDED IN THE LIPID BILAYER
  • Proteins are chains of amino acids, some of which
    are polar, others nonpolar.
  • The nonpolar parts (center) of a protein is
    attracted to the interior of the lipid bilayer,
    but is repelled by the water inside outside the
    cell.
  • The polar parts (ends) of the protein are
    attracted to the water on both sides of the lipid
    bilayer.
  • These attractions hold the protein in the proper
    position inside the lipid bilayer (cell
    membrane).

175
TYPES OF CELL MEMBRANE PROTEINS
  • 1 Cell-surface marker proteins attached to a CHO
    help define cell type (like a name tagliver,
    heart, blood, etc.)
  • 2 Receptor proteins recognize join with
    specific substances.
  • 3 Enzymes embedded in the cell membrane are
    involved in biochemical reactions inside the
    cell.
  • 4 Transport proteins aid in the movement of
    substances into out of the cell.

176
TYPES OF CELL MEMBRANE PROTEINS REVIEW
  • 1 Cell-surface marker proteins name tags
  • 2 Receptor proteins antennae for
    hormones/signals
  • 3 Enzymes speed up biochemical reactions
  • 4 Transport proteins doorways
  • REMEMBER
  • The cell membrane is fluid due to the lipids,
    allowing the proteins to move or float round
  • Imagine a wall with a floating door! They
    actually exist!

177
REVIEW
  • The cell theory has 3 parts.
  • Small cells function more efficiently than large
    ones because small cells have a higher
    surface-area-to- volume ratio than larger cells.
  • All cells have a cell membrane, cytoplasm,
    ribosomes, DNA .
  • Prokaryotic cells NO nucleus, NO organelles
  • Eukaryotic cells HAVE nucleus, organelles,
    cytoskeleton
  • The lipid bilayer of a cell membrane is made of a
    double layer of phospholipid molecules.
  • Proteins in cell membranes include enzymes,
    receptor proteins, transport proteins,
    cell-surface marker proteins
  • Sec 3-2 Q1-5 pg 60

178
ORGANELLES (pgs 55-66)
  • Little organs inside a cell,
  • much like our own organs.
  • These are the separate compartments inside a cell
    that perform specialized functions.
  • Organelles are suspended in CYTOSOL (fluid)
  • Organelles Cytosol Cytoplasm (solids fluid)
  • Organelles are ONLY found in eukaryotes.
  • (NOT in prokaryotes bacteria)

179
EXAMPLES OF ORGANELLES
  • 1 Nucleus
  • 2 Nucleolus
  • 3 Ribosomes
  • 4 Endoplasmic reticulum (ER) rER sER
  • 5 Golgi apparatus
  • 6 Cell membrane ( cell wall if present)
  • 7 Mitochondria
  • 8 Lysosomes
  • 9 Peroxisomes
  • 10 Centrioles

180
NUCLEUS
  • Control center of a cell, brain
  • Surrounded by a double membrane called the
    nuclear envelope or nuclear membrane.
  • Ribosomal proteins RNA are made here
  • Ribosomes are partially formed in a central area
    of the nucleus called the NUCLEOLUS.

181
NUCLEAR DNA
  • Most of the cells DNA is stored in the nucleus.
  • Nuclear DNA stores genetic information.
  • It also contains the instructions for the proper
    amino acid sequence of each protein.
  • Proteins regulate chemical reactions many other
    cellular functions
  • THUS
  • The nucleus is the control center because it
    regulates cell structure function by
    controlling protein production.

182
DNA CHROMOSOMES
  • Most of the cells DNA is stored in the nucleus
  • DNA exists most of the time in the form of
    elongated strands or strings.
  • When a cell is about to divide, DNA strands wind
    into a compact rod shaped form called
    Chromosomes.
  • These are not visible unless cell ready to
    divide.
  • DNA is the yarn, Chromosomes are the skeen,
    Genes are the designs/ stripes in the skeen.

183
NUCLEOLUS
  • Very center of the nucleus
  • Completely enclosed by the nucleus
  • Houses RNA

184
NUCLEAR ENVELOPE
  • Sometimes called the nuclear membrane
  • It completely encloses the nucleus, skin
  • Made of 2 lipid bilayers that separate the
    nucleus from the cytoplasm
  • Small channels called nuclear pores cover its
    surface
  • These pores allow RNA to move out of the nucleus
    into the cytoplasm of the cell.

185
RIBOSOMES
  • They make protein! HOW?
  • 1 The genetic code of DNA is translated into
    mesenger RNA (mRNA) in the nucleus.
  • 2 mRNA leaves the nucleus through nuclear pores
    in the nuclear envelope, heads to the ribosomes.
  • 3 Ribosomes chemically read the translated code
    on the mRNA strands link amino acids together
    in the correct sequence to make a protein. The
    mRNA holds a translation of DNAs instructions on
    which order to place the amino acids in to make a
    specific protein.

186
ENDOPLASMIC RETICULUM (ER)
  • Endo- inside, -plasmic cytoplasm
  • Reticulum network or system
  • ER a network inside the cytoplasm of a cell
  • The ER is a system of internal membranes that
    move proteins other substances throughout the
    cell.
  • The membranes are made up of a lipid bilayer with
    embedded proteins.
  • Its usually directly attached to the inside of
    the
  • cell membrane.
  • ER is divided into the rough ER the smooth ER.

187
ROUGH ER (rER)
  • This is the part of the ER that houses ribosomes.
  • RECALLRibosomes make protein
  • The rER helps transport the proteins made by the
    attached ribosomes, like a railroad next to a
    factory.
  • As a protein is made, it passes through the ER
    membrane into the hollow of the ER tube.
  • The completed protein becomes surrounded as a
    piece of the ER wall is pinched off to form a
    Vesicle
  • (fatty sac) around the new protein like a
    package.

188
VESICLES
  • Vesicles are a small membrane sac that transports
    substances in a cell.
  • They are usually made from the pinched off walls
    of an organelle or a lipid bilayer.
  • EX-Vesicles can be made from the walls of the ER,
  • Golgi apparatus, cell membrane.

189
SMOOTH ER (sER)
  • Part of the ER that lacks ribosomes
  • (that is why its smooth!).
  • Its downstream from the rough ER (rER).
  • It simply exists as a tube through which vesicles
    (containing proteins and other substances)
    travel.
  • The sER makes phospholipids to maintain patch
    the cell membrane.
  • It also detoxifies toxins like alcoholliver
    cells contain many lengths of sER.

190
GOLGI APPARATUS
  • Named after ________ Golgi
  • Set of flattened, membrane-bound sacs that serve
    to package distribute proteins.
  • Enzymes in the Golgi apparatus modify the
    proteins.
  • Modified proteins are repackaged into new
    vesicles that form from the pinched-off lipid
    surface of the Golgi apparatus.

191
CELL MEMBRANE
  • Acts as a skin to protect hold the cell
    together.
  • However, vesicles can flow through the cell
    membrane easily as to export its contents
    outside the cell.
  • When vesicles empty their contents outside the
    cell, the process is called EXOCYTOSIS, meaning
    to exit the cell.

192
THE MIGHTY MITOCHONDRIA
  • Mitochondrion if singular, (2 Mitochondria)
  • This is the organelle that harvests energy from
    organic compounds to make ATP, the main energy
    currency of cells
  • This is the Powerhouse of the Cell.
  • Cells with a high energy requirement, like muscle
    cells, may contain thousands of mitochondria.

193
MITOCHONDRIAL STRUCTURE
  • It has both an inner an outer membrane
  • The outer is smooth, the inner is folded to
    increase the surface area for chemical
    reactions.
  • Chemical reactions occur in both membranes to
    produce ATP, but mostly on the folded inner
    membrane because there is more room.
  • Mito pic! needed

194
MITOCHONDRIAL FUNCTION
  • These are the sites of energy production.
  • C6H12O6 6O2 ? 6CO2 6H2O
    E
  • glucose oxygen carbon dioxide water
    energy
  • This chemical equation makes life on Earth
    possible.
  • Cellular respiration is photosynthesis in reverse!

195
WHAT HAPPENS TO THE ENERGY?
  • Adenosine triphosphate (ATP) is the energy saver
    of the cell.
  • ATP works like a battery to temporarily store
    energy
  • High energy bonds exist between the last 2 PO4 s
  • A-PO4-PO4 PO4
  • EACH molecule of glucose charges 38 ATPs !!!

196
ATP
  • Adenosine triphosphate, a nucleotide
  • It is the main energy currency of cells.
  • Some ATP is produced in the cytoplasm,
  • but the majority is produced by mitochondria.
  • The ATPs circulates throughout the body
    dispersing energy needed for skeletal muscles
    the heart, as well as the energy needed to start
    chemical reactions for life, memories, dreams,
    to name a few uses.
  • Anywhere energy is needed, ATP supplies.

197
MITOCHONDRIAL DNA
  • Mitochondria also have their own DNA, ribosomes,
    produce some of their own proteins!
  • Mitochondrial DNA is independent of nuclear DNA
    is similar to the circular DNA of bacteria.
  • The widely accepted Endosymbiotic Theory, states
    that prokaryotes may be the ancestors of animal
    mitochondria, that at 1 time they were free
    living organisms that formed a mutual
    relationship with another cell!

198
ENDOSYMBIOTIC THEORY?
199
LYSOSOMES
  • Small vesicles (also considered organelles) that
    contain a cells digestive enzymes.
  • This is one type of vesicle that contains a
    protein (enzyme) formed by the Golgi apparatus
    that stays inside the cell for its function it
    does not leave the cell by the process or
    exocytosis.
  • The PEROXISOME is another example of a vesicle
    that remains inside the cell.

200
LYSOSOME FUNCTIONS
  • They often migrate to mitochondria to digest
    glucose to release energy used to charge ATP.
  • Others are used to eat bacteria, germs, invaders.
  • Also used to recycle wornout/defective
  • organelles cells.
  • Lots of them are inside WBCs (white blood cells)
  • for immunity (eating germs).

201
PEROXISOMES
  • Enzyme-filled vesicles that digest fats.
  • RECALL...fats long chains of nonpolar fatty
    acids
  • Peroxisomes are also made by the Golgi apparatus
    stay inside the cell, like lysosomes.
  • They are involved in removing poiso
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