The Oregon Clinical and Translational Research Institute OCTRI

1
The Oregon Clinical and Translational Research
Institute (OCTRI)

• Aim 1 Develop an academic home (the OCTRI)
  that is specifically devoted to clinical and
  translational research, with experienced and
  dedicated leadership, excellent resources, and
  outstanding institutional commitment.
• Aim 2 Engage and nurture a new cadre of
  highly-trained, interdisciplinary investigators
  through a strong, diverse educational curriculum.
• Aim 3 Create a Research Commons a
  coordinated infrastructure of core research tools.

2
VP Research Dan Dorsa
OCTRI Organizational Structure
External Advisory Committee
Director Eric Orwoll Assoc VP Research,
OHSU Assoc Dean SOM
Deans Council

• Education
• Cindy Morris
• - K12
• - T32
• - K30 (HIP)

Assoc Director Mary Durham VP Research,
KP Director, CHR
Deputy Directors/Discoverers Hornbrook, Jacoby,
Steiner
The CTSI Academy
Administrative staff Denise Ellis
Scientific Review Committee (SRC) Chair, Dan
Marks MD, PhD
Steering Committee
Front Door
Pilot Program Funding
Evaluation Jim Huntzicker P. Beemsterboer Julie
Hollister-Smith
ISIS Darlene Kitterman
CTRC Mary Samuels
Biostatistics Tomi Mori
Informatics Bill Hersh Pierre LaChance Shannon
McWeeney Rob Schuff
TRIPP Mary Durham
Community-based Research Resources Patty Carney
Core Technologies Susan Hayflick
3
Biostatistics Design Program

• Overall Mission
• To enhance the quality and quantity of clinical
  and translational research at OHSU and KPCHR
  through biostatistics collaboration, research and
  education.
• Specific Aims
• Aim 1 Establish a biostatistics and research
  design home
• Aim 2 Establish a biostatistics service unit
• Aim 3 Develop a research unit for innovative
  biostatistics methodology
• Aim 4 Create a biostatistics education unit

4
Progress

• Pre-CTSA Program Status
• Disparate, fragmented biostatistics units at OHSU
  and KPCHR
• 3 GCRC statisticians (1.30FTE) focused on GCRC
  protocol and clinical research support
• 6 Month Progress
• Created a biostatistics and design home
• 8 faculty (1.80FTE) and 4 staff (.95FTE)
• Faculty and staff recruitment in progress
• Regular bi-monthly program meeting
• KPCHR, Community Program and Informatics Program
  liaisons
• Project triage system
• Transition plan for GCRC protocol support
• Assisted 111 project requests from 96
  investigators
• 54 data analysis consultations, 32 grant
  applications, 25 CTRC protocol development

5
Challenges

• Managing expectation, demands and core capacity,
  while protecting academic development of the
  program faculty
• Balancing achievements for all four aims
• Growth model and strategic recruitment plan
• Securing space
• Spreading CTSA support to several faculty with
  various biostatistics and design expertise
• Fostering collaborative research
• Recruitment and retention issues
• No MS and PhD programs in biostatistics at OHSU
  or KPCHR
• Competitive market salary and benefits
• Funding for education activities
• Education funding tied to specific graduate
  programs

6
Priorities

• OHSU BDP
• Faculty recruitment
• Development of strategic growth model
• Establish an effective intra- and
  inter-programmatic communication and coordination
• Tracking and evaluation
• Protected time for statistical method development
• Prioritization of support activities
• Foster research collaboration with a partner
  organization (KPCHR)
• All CTSA funded institutions
• Mechanism to share expertise across CTSA funded
  institutions
• Mechanism to share educational materials,
  algorithms, methods and software across CTSA
  funded institutions