Hallucinogens

1
Hallucinogens

• Indoleamine and Phenylethylamine Drugs
• Types
• Effects
• Pharmacology
• Dissociative anesthetics
• Types
• Pharmacology

2
Types of I and P Hallucinogens

• Mescaline
• Psilocybin, DMT, 5-MeO-DMT
• LSD

3
Effects of I P Hallucinogens

• Psychological
• Trip
• Onset
• Plateau
• Peak
• Come-down
• Physiological

4
Pharmacology of I P Hallucinogens

• Serotonin-like structure
• Agonists
• Binding
• Hallucinations
• Tolerance
• Dependence

5
Pharmacology of I P Hallucinogens

• Negative Consequences
• Bad Trips
• Flashbacks
• HPPD
• Psychosis

6
PCP and Ketamine

• Pharmacology
• Route of Admin
• Tolerance
• Reinforcement

7
PCP and Ketamine

• Mechanism
• NMDA receptors
• Relationship to schizophrenia?

8
Salvia Divinorum

• Salvinorin A
• Routes of Administration
• Smoking
• Oral
• quid
• Vaporization
• Levels of Experience
• S-A-L-V-I-A
• Legality