Myocardial infarction

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Myocardial infarction
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Whats Myocardial infarction?

• A disease results from the partial interruption
  of blood supply to a part of the heart muscle,
  causing the heart cells  to be damaged or die.

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Classification of MI

• 1-Transmural infarct
• 2-Subendocardial infarct
• 3-Intramural infarct

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causes
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MI results from occlusion of one of the coronary
arteries which can be from

• Atherosclerosis
• Coronary thrombosis/embolism
• Platelet aggregation
• Coronary artery stenosis/spasm
• Decrease blood flow with shock and/or
  hemorrhage.
• Direct trauma.

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Pathophysiology
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• Interfere with the function of ventricular myocard
  ial infarction and predisposes to hemodynamic
  changes that include
• The decline of contraction, decreased stroke
  volume, abnormal wall motion, decreased ejection
  fraction, increased left ventricular volume at
  end systole and end diastole, and increased
  ventricular end-diastolic pressure.

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• . Compensation mechanism cardiac output and
  perfusion which may include reflex
  sympathetic stimulation to increase heart rate,
  vasoconstriction, ventricular hypertrophy, as
  well as water retention with myocardial demands

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