Food/Drug Interactions

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Food/Drug Interactions

• M. Burns, PhD, RD
• FCS 4751

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Drug therapy

• Long-term care
• Numerous drugs
• Therapeutic side effects
• Alters nutritional status

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JCAHO

• Joint
• Commission
• Accreditation
• Healthcare
• Organizations

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Drug-induced malnutrition

• Numerous meds at one time
• Sudden increased need
• Genetics
• Body composition

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High-risk Groups

• Developing fetus, infants
• Pregnant women
• Elderly
• Chronically ill

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What is a drug?

• Chemical that interacts with a living organism to
  produce physiologic response

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What is bioavailability?

• Proportion of drug that passes into the
  circulation
• Reflects both ABSORPTION and METABOLIC USE

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Remember...
with increased meds there is an increased chance
for drug-nutrient interactions.
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Commonly affected nuts

• Calcium
• Folate
• Pyridoxine
• Vitamin A

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Effects on Nutl Status

• Dietary intake
• Increase or decrease appetite
• Alter taste sensation
• dysgeusia
• hypogeusia
• unpleasant aftertaste

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Effects on Nutl Status

• Affects nutrient absorption
• Influence transit time
• Affect bile acid activity
• Change GI environment
• Damage mucosal lining

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Effects on Nutl Status

• Affects nutrient metabolism
• Antivitamins
• MAO inhibitors
• tyramine-restricted diets
• Anticonvulsants

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Metabolism, cont.

• Oral conceptives
• Anti-inflammatory drugs
• Anti-hypertensive drugs
• diruetics, beta-blockers
• HIV meds

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Successful RDs will...

• Include meds in SOAP note
• Assess nutl status in regards to interactions

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Next Time

• Complementary Medicines
• Read 2 articles on my door