An Academic Health Sciences Centre at the heart of a world city....

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An Academic Health Sciences Centre at the heart
of a world city....
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The partners four highly-performing
institutions each bringing complementary and
distinctive contributions

• Excellence in clinical service
• Comprehensive portfolio of excellent quality
  innovative services
• International recognition in renal and liver
  disease, dermatology, haematology, childrens,
  neurosciences, foetal medicine and mental health

• Excellence in education
• Unique breadth of education and training to 9,500
  students
• At the forefront of innovation and exploiting new
  technology
• Capacity building for translational research

• Excellence in research
• One of top 5 biomedical research universities in
  UK (2008 RAE)
• Six MRC Centres, three NIHR Research Centres and
  BHF Centre of Excellence
• Institute of Psychiatry and SLaM leading mental
  health research centre in Europe

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Collaboration working to make London a leading
healthcare city
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Strategic priorities existing excellence,
emerging strengths
Emerging strengths of relevance to the local
population
Existing comprehensive international profile,
excellence in research and clinical service
delivery

• Neuroscience, Neurological Disease and Mental and
  Behavioural Disorders
• Cardiovascular Disease, including Imaging
• Asthma, Allergy, Environment and Health
• Oral Disease / Dentistry
• Transplantation, Regenerative Medicine / Stem
  Cells
• Dermatology
• Medical Genetics

• Diabetes, Obesity and Metabolic Disease Healthy
  Living
• Cancer, including Palliative Care and Cancer
  Imaging

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The population focus on local health needs and
reducing inequalities
Health Indicator
Binge drinking adults
Deaths from smoking
Drug Misuse
Early deaths Cancer
Early deaths Heart disease stroke
Healthy eating adults
Hospital stays due to alcohol
Infant Mortality
Life expectancy
Mental Illness
Obese Adults
Obese Children
Physically active adults
Teenage Pregnancy
Tuberculosis
Violent Crime
Source Department of Health Community Health
Profiles 2008
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The vision a radical change in healthcare

• To advance health and well-being by integrating
  world-class research, care, education and
  training through
• Translating research more rapidly into clinical
  practice and effectively disseminating these
  advances through education and training
• Harnessing the power of discovery science to
  transform the nature of healthcare by moving from
  treatment towards population screening and
  disease prevention
• Recognising the special needs and inequalities in
  health among the local population and addressing
  these through earlier intervention and
  personalised medicine, as well as helping local
  people to maintain, improve and enhance their
  health

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The structure Clinical Academic Groups
Cardiovascular
Dementia and Older Peoples Mental Health
DiabetesandObesity
Other Clinical Academic Groups
All clinical services and translational
research Strategy for delivery of the
tripartite mission Devolved budgets
CLINICAL ACADEMIC GROUPS
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The structure accelerating translation and
disseminating knowledge
Cardiovascular
Dementia and Older Peoples Mental Health
DiabetesandObesity
Other Clinical Academic Groups
CLINICAL ACADEMIC GROUPS
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The structure integrating leadership and
linking resources to the vision
Cardiovascular
Dementia and Older Peoples Mental Health
DiabetesandObesity
Other Clinical Academic Groups
CLINICAL ACADEMIC GROUPS
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Cardiovascular CAG added value of the AHSC

• Non-invasive aortic valve replacement delivered
  jointly across GSTT and KCH
• Primary PCI first 24/7 programme in UK, pilot
  site for the DH, 400 patients p.a.
• MR-guided cardiac catheterisation N.B. for
  electrophysiology

Clinical innovation
Research

• Integration of basic science and clinical
  programme e.g. ischaemia reperfusion,
  cytoprotection, novel interventions monitored by
  MR

Education and Training

• Dissemination of best practice to local networks
  and beyond

• Public education to raise awareness / access
• Ethnicity and risk
• Non-invasive diagnosis of EC dysfunction
• Targeted early intervention

Prevention
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What will be different? Shorter translational
pathways

• We will
• Work with partners in our local communities to
  identify ill-health at the earliest possible
  opportunity
• Train all of our nurses to ensure that every
  patient has the opportunity to grant their
  consent to participate in research during their
  first contact
• Build on the CRIS IT system to optimise the
  ability to utilise the clinical patient record to
  support research
• Create a biobank to inform research through
  taking samples during treatment from all
  consenting patients
• Ultimately
• Providing the best and most up-to-date treatments
  and the best service delivered consistently by
  the best trained staff in the most appropriate
  setting to ensure the best outcomes for all of
  our patients

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What will be different? Benefits for patients
Four independent organisations with different
visions and investment priorities
Partnership with integrated leadership, shared
purpose and investment priorities
CAGs responsible for developing and delivering
the tri-partite mission
Lack of integration of clinical, research and
education due to organisational barriers
Long translational cycle time with low levels of
patient participation in research
Shorter translational pathways delivered through
our new research infrastructure
Faster and wider dissemination of knowledge
through the Education Academy
Slow adoption of innovation and best practice
locally, nationally, internationally
Increased resources invested in prevention and on
delivering care in the community
Focus of clinical and academic resources on
treating ill-health in a hospital setting
General poor health of our local population with
wide inequalities in health and access
Reduced inequalities, better health through most
up-to-date treatments to patients