Building Bridges Developing elearning tools to bring universal ethical review across cultures and di

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Building BridgesDeveloping e-learning tools to
bring universal ethical review across cultures
and disciplines

• Marie Hirtle
• TRREE-for Africa
• AREC Spring Conference Programme
• March 14, 2008

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Todays discussion

• A. Focus TRREE-for Africa initiative
• Who?
• What?
• How?
• B. Model On-line tutorial in research ethics
  (Canada, Québec)

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TRREE-for Africa Who ?
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TRREE-for Africa Partners and funders

• EDCTP European and Developing Countries Clinical
  Trials Partnership
• Swiss academy of medical sciences
• Commission for Research Partnerships with
  Developing Countries
• Canadian Institutes of Health Research

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TRREE-for Africa What

• Training and capacity building initiative
• e-Learning
• e-Resources
• Bilingual (French-English)
• Freely available
• Open code software

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Proposed structure e-Learning
LEVEL 1 General Concepts
Module 1 Introduction
Module 2.1 Ethics evaluation
LEVEL 2 Key responsibilities
Module 2.2 Research Partners
Module 2.3 etc.
LEVEL 3 National requirements
3.1 Country A
3.2 Country B
Level 4 Pressing themes
Module 4.1
Module 4.2 etc.
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Proposed first phase (yellow) and additional
content (white) of website

• e-Learning

e-Resources
Laws, regulations, policies guidelines from
International, regional bodies Mali, Cameroon,
Tanzania, South Africa, Sénégal, Nigeria Canada,
Switzerland, Germany
2 modules from levels 1, 2 or 4
To be chosen
To be chosen
Level 3 modules
Mali
Other African countries ? Other countries ?
Cameroon
Tanzania
Bilingual Glossary, bibliography, Hyper links
From Adv B. ?
Links to other sites and resources
Jurisdictional and thematic
Switzerland, Germany Canada etc. ?
Events calendar? TRREE documents ...
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TRREE-for Africa How

• Collaborative
• Collegial
• Bi-directional
• African perspective with-in an international
  perspective
• Based on universal principles of ethics

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TRREE- Setting priorities (1)

• Needs assessment Questionnaire
• Submitted to ethics committee members
• Cameroon, Mali Tanzania
• 109 contacted / 255 total in 3 countries
• 68 response rate (74/109)
• ANALYSIS BY JÉRÔME ATEDJIEU

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TRREE- Setting priorities (2)

• Summary of Results of the NAQ
• 71 of respondents already had some sort of
  training in ethics
• Priority in terms of content
• Fundamental principles of ethics
• Applicable normative framework
• How to conduct ethics review
• Audience
• REC members researchers

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TRREE- Setting priorities (3)

• Training objectives
• Be able to identify principles of ethics relevant
  to a given protocol
• Be able to identify relevant regulatory
  provisions
• Understand importance of ethics review promotion
  of the highest ethical standards and the
  protection of humans who participate in research
• Understand the mandate of RECs

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TRREE e-learning content phase 1

• e-Learning

e-Resources
Laws, regulations, policies guidelines from
International, regional bodies Mali, Cameroon,
Tanzania, South Africa, Sénégal, Nigeria Canada,
Switzerland, Germany
2 modules
MODULE 1 INTRODUCTION
MODULE 2 REC
Level 3 modules
Mali
Cameroon
Tanzania
Bilingual Glossary, bibliography, Hyper links
Switzerland
Links to other sites and resources
Jurisdictional and thematic
TRREE documents ...
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Model On-line tutorial- QC, Canada

• Format of e-learning http//ethique.msss.gouv.qc.
  ca/didacticiel/
• Short didactic texts
• Case studies
• Q A
• Charts and tools
• Bilingual Glossary
• Hyperlinks to relevant texts

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Model On-line tutorial-QC, Canada

• M1 Bringing about more good than harm

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Model On-line tutorial-QC, Canada

• M2.2 Evaluating Risks and Potential Benefits

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Model On-line tutorial-QC, Canada

• MODULE 3.1 Ethical analysis of and harms in
  research

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Model On-line tutorial-QC, Canada

• MODULE 3.1 Ethical analysis of and harms in
  research

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Building bridges

• Partnership
• debates about substantive issues (consent,
  Standard of care)
• Consensus building on basic principles
• Bi-directional
• Cross-fertilization of training material
• Pre-requisite (public) research sponsors
• Pre-requisite for further training opportunities
  ?
• Sustainability

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Building bridges

• Phase 2
• including more countries from Africa and Europe
• Developing training for more audiences
• Covering more topics themes
• Adding more languages?

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TRREE-for Africa

• Thank you
• www.trree.org