Kay Etzler

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NIH SBIR/STTR Funding OpportuNIHtieS
National Institutes of Health

• Kay Etzler
• SBIR/STTR Program Analyst
• Office of Extramural Research, NIH

AAMU 2007 SBIR/STTR Small Business
Conference Knight Center, Alabama AM
University January 29, 2008
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NIH Mission
Improve human health through biomedical and
behavioral research, research training and
communications.
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Small Companies Can Help NIH meet its mission

• Conduct innovative R/RD that results in product,
  process, or service that will...
• Improve patient health
• Speed process of discovery
• Reduce cost of medical care/cost of
• research
• Improve research communication
• tools

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Organizational Structure of NIH
Office of the Director
National Institute on Alcohol Abuse and Alcoholism
National Institute of Arthritis
and Musculoskeletal and Skin Diseases
National Cancer Institute
National Institute on Aging
National Institute of Child Health and
Human Development
National Institute of Allergy and Infectious
Diseases
National Institute of Dental and Craniofacial Rese
arch
National Institute of Diabetes and Digestive
and Kidney Diseases
National Institute on Drug Abuse
National Institute of Environmental Health
Sciences
National Institute on Deafness and
Other Communication Disorders
National Eye Institute
National Human Genome Research Institute
National Heart, Lung, and Blood Institute
National Institute of Mental Health
National Institute of Neurological Disorders
and Stroke
National Institute of General Medical Sciences
National Institute of Nursing Research
National Center on Minority Health and Health
Disparities
National Institute of Biomedical Imaging and
Bioengineering
National Center for Complementary and
Alternative Medicine
National Library of Medicine
Fogarty International Center
National Center for Research Resources

No funding authority
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NIH Institute/Center SBIR/STTR Budget
Allocations (FY2007)
Extramural RD Set-Asides SBIR 2.5 STTR
0.3
NCI
580.7M (SBIR) 70.0M (STTR)
NIAID
NHLBI
NIDDK
NIGMS
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Features of NIH SBIR/STTR Snapshot

• External Peer Review
• Experts from Academia and Industry
• 5 Criteria Significance, Approach,
• PI(s), Innovation, Environment

• SBIR and STTR Program
• Single Grant Solicitation Same topics
• Investigator-initiated research ideas
• Contracts Govt-initiated ideas
• NIH Guide for Grants and Contracts

• Multiple Receipt Dates
• April 5, August 5, December 5
• May 7, September 7, January 7 (AIDS)
• November 5 2007 Contract Solicitation

• Gap Funding Programs
• No-Cost Extensions
• Phase I/Phase II Fast Track
• Competing Renewal Phase II awards
• Administrative Supplement Awards

• Multiple Award Mechanisms
• Grants, Contracts, Cooperative Agreements

• Budget and Project Period
• 100K/6 months (Ph I)
• 750K/2 yrs (Ph II)
• Deviations when scientifically appropriate for
  success of the project.

• Technical Assistance Programs
• Ph I Technology Niche Assessment
• Ph II Commercialization Assistance
• Ph II Manufacturing Assistance
• Both Pipeline to Partnerships (P2P)

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Multiple Award Mechanisms

• Grants (95)
• Single SBIR/STTR Solicitation
• Guide for Grants and Contracts
• Investigator-initiated research ideas NIH
• Contracts (4-5)
• SBIR only
• Government-initiated ideas
• Cooperative Agreements (lt1)
• SBIR/STTR
• Government staff involvement
• Typically, clinical studies

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Multiple Solicitations and Receipt Dates

• SBIR/STTR Omnibus Grant Solicitation (NIH, CDC,
  and FDA) Parent FOAs
• Release January Receipt Dates April 5, Aug 5,
  Dec 5
• (AIDS/AIDS-related May 7, Sept 7, Jan 7)
• SBIR Contract Solicitation (NIH, CDC)
• Release August Receipt Date November 5,
  2007
• NIH Guide for Grants and Contracts
• Release Weekly Receipt Dates Specified in
  each FOA

SBIR PA-08-050 STTR PA-08-051
Closed
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HHS/NIH Program Funding
Propose a Realistic and Appropriate Budget for
the Research Key Take Home Message
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NIH SBIR/STTR Success Rates
Fiscal Year 2006
640 M SBIR/STTR
355
41.4
26
10
Success Rate ()
41
684
153
26.0
25
21.4
19.8
19.4
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Review Considerations

• External Peer Review
• Two-tiered process (6-9 months)
• Subject experts from Academia and Industry
• Criteria (equally weighted)
• Significance
• Approach
• PI(s)
• Innovation
• Environment

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Mind the Gap

• Gap Funding Programs
• No-Cost Extensions
• Phase I/Phase II Fast Track
• Competing Renewal Phase II awards
• Administrative Supplement Awards

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Research Topics
Examples from 200 pages of topics!
Our Ideas Biodefense Biosensors Nanotechnologies
Bioinformatics Diagnostic and Therapeutic
Devices Telehealth
Biosilicon devices Biocompatible
materials Acousto-optics / opto-electronics Imagin
g devices Genetically engineered
proteins Proteomics / Genomics
http//grants.nih.gov/grants/funding/sbirsttr1/200
8-2_SBIR-STTR-topics.doc
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Research Topics
Your Ideas

• Investigator-initiated RD projects

Angioscopes to Zebrafish

• Research projects related
• to the NIH mission

• Other Research areas within the mission of an
  awarding component

Key Take Home Message
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Deploying Medical Innovations to the Marketplace
Transitioning to the Marketplace
Phase I
Phase II
Phase III
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Technical Assistance Programs
Business strategic planning Builds alliances
and investor partnerships

• Commercialization
• Assistance

(Phase II awardees)
Partnership with NIST MEP Centers Help make
better manufacturing and operational decisions
Manufacturing Assistance
(Phase II awardees)
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To (the) Market We Go
NIH Pipeline to Partnerships (P2P)
Technology Showcase Potential partners search for
technologies of interest Facilitates matchmaking
between NIH SBIR/STTR awardees and potential
strategic partners and investors
(Ph I and Ph II awardees)
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Stay Informed

• NIH SBIR/STTR Web site http//grants.nih.gov/gra
  nts/funding/sbir.htm
• NIH Guide for Grants and Contracts (weekly
  notification)
• http//grants.nih.gov/grants/guide/listserv.htm
• NIH SBIR/STTR Notification http//grants1.nih.gov
  /grants/funding/listserv.htm
• Contact NIH SBIR/STTR Program Staff
• Listed in Solicitations under each IC

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NIH Success Storieshttp//grants1.nih.gov/grants/
funding/sbir_successes/sbir_successes.htm
Novera Pharmaceuticals (KY)Dr. William Ehringer
Intralase Corporation (CA) Dr. Tibor Juhasz
Direct Cellular Energy (ATP) Delivery System
Cell preservation, growth and wound healing
Corneal Surgery with Femtosecond Lasers
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Real Solutions..Real Problems. Real People
Lab to Life
Todays Ideas
Tomorrows Discoveries
A Better Future for All Americans
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Jo Anne Goodnight NIH SBIR/STTR Program
Coordinator Phone [phone] Fax
301-480-0146 Email jg128w_at_nih.gov
Kay Etzler SBIR/STTR Program Analyst Phone
301-435-2713 Fax [phone]
Email etzlerk_at_od.nih.gov
http//grants.nih.gov/grants/funding/sbir.htm