Gut Health, Food Sensitivities and Weight Loss

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• Gut Health,
• Food Sensitivities
• and Weight Management

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Gut Health, Inflammation and Weight

• Is there a connection?
• Gut Health
• Microbiome
• Leaky Gut
• Inflammation
• How to Improve Gut Health Decrease Inflammation

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CHRONIC DISEASE Its Never One Thing!
Lifestyle Dietary Factors
Environmental Factors
Gut Dysbiosis
Inflammation
Food Sensitivities Pathogens
Obesity
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Inflammation Chronic Disease Gut Integrity
Matters

• 95 of all chronic disease has an inflammatory
  component.
• Gut integrity prevents or sets the stage for food
  sensitivity, immune dysfunction, inflammation,
  chronic disease.
• Determining removing foods that cause
  inflammation can be an important part of breaking
  the cycle of chronic inflammation
• Improving gut health reduces inflammation and may
  decrease obesity.

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Overall Gut Function

• GI tracts major roles
• Digestion and uptake of nutrients
• Over 70 of bodys immune systems is in the GI
  tract
• Gut decides what is friend or foe.
• OVERALL HEALTH STARTS IN THE GUT

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Gut Microbiome Functions

• Contains over 1000 species of bacteria, yeast and
  parasites
• Synthesis of vitamins (K, B12)
• Metabolism
• Renewal of gut cells - lining
• Development of the immune system
• Motility

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Normal Gut
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Leaky gut is a gateway to chronic disease
NSAIDs
Food allergies Intolerances
Immune system dysregulation
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Leaky Gut - Inflammation - Weight

• Food choices, eating habits, digestion, the gut
  flora, and elimination ..
• all influence the integrity of the gut
• Leads to Leaky Gut
• Gut health prevents or sets the stage for food
  sensitivity ultimately immune dysfunction,
  inflammation, chronic disease including
• DIFFICULTY LOSING WEIGHT

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Some Causes of Leaky Gut
or .... Losing Barrier Integrity

• Chronic Stress
• Intestinal Infections
• Small intestine bacterial overgrowth
• Environmental contaminants
• Excess alcohol
• Poor diet
• Diet soda
• NSAIDS, steroids, antibiotics, and other
  medications

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How do we Improve Gut Microbiota?

• Eat a clean diet
• Gut health supplements
• Decrease stress
• Fecal transplant?
• Determine and eliminate food sensitivities

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How Do Food Sensitivities Impact Gut Health?

• Development of FS is the end result of multiple
  inter-related chronic problems of the digestive
  tract, such as poor digestion, abnormal bacterial
  growth within the gut, and chronic gut
  inflammation.
• Determining removing foods that cause
  inflammation can be an important part of breaking
  the cycle of chronic inflammation (i.e. Food
  Sensitivity Testing).

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The Connection Between Food Sensitivities Weight

• Food sensitivities alter your biochemical
  balance, influencing appetite controlling
  hormones like serotonin and ghrelin.
• Result abnormal cravings for simple sugars and
  carbohydrates.
• Your metabolism is disrupted resulting in less
  efficient energy production and increased fat
  storage.
• Food sensitivities provoke immune mediated
  vasculitis, which causes fluid to leak from your
  capillaries into surrounding connective tissues.
• Result water retention and inflammation.

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Food Allergy or a Sensitivity

• Food Allergy
• Food Sensitivity

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Allergy or Food Sensitivity

• Anaphylactic Allergy
• Immediate/severe symptom onset Specific immunity
• Genetic/Exposure related IgE mediated
• Induce Mast cells/Basophils to release Histamine
• Skin test/RAST
• Peanut, milk, egg, fish, shell fish, wheat, nuts,
  soy

• Sensitivity
• Genetic/Exposure Related
• Delayed symptom onset
• Generally less severe but chronic symptoms
• Altered Gut Integrity
• Remove food to break the cycle of chronic
  inflammation
• As many neurons in gut as along spine
• 90 percent of the body's serotonin is made in the
  digestive tract.

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Importance of Food Sensitivity Testing
We suspect there is a common soil which both
cardiovascular disease and diabetes share, and
that this common underlying cause may be
inflammation. Dr. Paul M. Ridker,
Cardiologist Brigham and Womans Hospital Boston,
Massachusetts

• Chronic inflammation is associated with most
  disease
• 68.5 of adults are overweight or obese
• CVD is the leading cause of death for both men
  and women in the U.S.
• About 20 of the population suffers from IBS
  related symptoms
• Over 25 Million People in the U.S. have Diabetes
• The NIH estimates up to 23.5 M Americans suffer
  from autoimmune disease

Source Ogden C. L., Carroll, M. D., Kit, B.K.,
Flegal K. M. (2014). Prevalence of childhood and
adult obesity in the United States, 2011-2012.
Journal of the American Medical association,
311(8), 806-814. Source Murphy SL, Xu JQ,
Kochanek KD. Deaths Final data for 2010. Natl
Vital Stat Rep. 201361(4). Source Centers for
Disease Control and Prevention. National Diabetes
Statistics Report Estimates of Diabetes and Its
Burden in the United States, 2014. Atlanta, GA
US Department of Health and Human Services
2014.  
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• Who
• Should
• Test?

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Food Sensitivity Testing

• Identifies substances that provoke a negative
  cellular response.
• Dose dependent with Delayed onset.
• Any food can cause symptoms. With repeated
  consumption, can develop into a chronic
  systematic inflammatory response and the constant
  activation of the immune system.
• Single elimination trials take a very long time.
• NO universal bad or good foods very patient
  specific.

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Cellular Degranulation Reaction (inducing
mediator release)
The reactive white blood cells release chemical
mediators that affect target organs and may
result in symptom manifestations typical in many
chronic conditions.
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What is the Quickest Way to Get Relief?

• Remove the food or chemicals that are triggering
  the immune response

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What is the Biggest Challenge for Food
Sensitivities?

• Identifying Your Reactive Foods

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ALCAT BLOOD TEST

• Most accurate way to identify foods/chemicals
  that provoke an immune response.
• Direct link to systematic inflammation and
  constant activation of the immune system
  difficulty losing weight.
• Test over 450 antigens, including Foods,
  Environmental Chemicals, Food Additives
  Colorings, Molds, Functional Foods Medicinal
  Herbs, Pharmocoactive agents.
• Proven results with patient compliance to
  recommended food avoidance rotation diet.

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Studies have established that it can be a useful
screening tool for the identification of foreign
substances that may trigger immune cell
activation, particularly of neutrophils, leading
to inflammatory disorders. The ALCAT test,
coupled with a targeted diet that is individually
tailored according to the tests results, may
support immune homeostasis and provide a valuable
complementary approach for therapy and overall
health. (Altern Ther Health Med.201521
(4)42-52).
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Effect of Alcat-Based Food Elimination on
Inflammatory Markers, Body Composition and
Medical SymptomsLukaszuk J, Shokrani M,
Hoppensteadt J, Umoren J.

• Pre/post test double blind study Tx (n87) and PL
  (n46).
• Follow 4 week elimination diet based on Alcat
  results.
• Blood samples, body composition and medical
  symptoms completed days 1 and 30.

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Alcat Study Conclusions

• Elimination of inflammatory foods have a positive
  impact on Body Mass Index.
• Alcat results may positively influence
  inflammatory responses, body composition and
  well-being.

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The Short Term Efficacy of the ALCAT Test of Food
Sensitivities to Facilitate Changes in Body
Composition and Self-Reported Disease Symptoms A
Randomized Controlled Study

• The ALCAT Test (exp. group) resulted in highly
  significant improvements in body composition and
  self-reported disease symptoms.
• 98 of those following the ALCAT plan either lost
  weight and/or improved body composition.

There was a marked reduction in cravings in
general, especially for sweets.
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Take Home Messages

• There is a connection between gut health and
  weight.
• Reducing inflammation is the key to overall
  health.
• Food and other exposures interact with our gut in
  either a positive or negative way.
  
• ALCAT individualizes your dietary regimen.
• Diet and lifestyle modifications improve gut
  health and reduce inflammation to maintain
  permanent weight loss.

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Thank You
For more information, contact Lea Russell
(813-857-7488) or Susan Drake (303-725-6558)