Oncology Cancer Drugs Market - PowerPoint PPT Presentation

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Oncology Cancer Drugs Market

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The term mechanism of action refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor. – PowerPoint PPT presentation

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Title: Oncology Cancer Drugs Market


1
Oncology Cancer Drugs Market
2
Summary
  • Oncology (1985-2016) - 157 cancer drugs  -
    Ranking and detailed regulatory approval
    profiles is a comprehensive drug ranking and
    profiling report that ranks cancer drugs based on
    total approvals and unique approvals received in
    US, Europe and Japan. It provides the regulatory
    approval details of each drug for the past 30
    years (1985-2016) in both the tabular and (an
    interesting) infographic formats. Additionally,
    the basic drug-specific information such as first
    approvals, breakthrough,
  • orphan designations, black box warnings, etc., is
    also
  • presented along with negative developments of
    drugs
  • recalled, discontinued and withdrawn.

3
(No Transcript)
4
Part 1 The basic information section covers
  • Trade names Drugs are often known by different
    brand names (trade names) in different
    geographies. For instance, Rituxan is the trade
    name for Rituximab in the US, whereas it is known
    as Mabthera in Europe. We have presented each
    drugs trade name used in different geographies
    in our report.Companies involved in marketing
    Drugs are often sold or
  • marketed in different geographies by different
    companies.
  • For instance, Aranesp is marketed in the US and
    Europe by
  • Amgen, whereas in Japan it is marketed by
  • Kyowa Hakko Kirin.

5
  • Active pharmaceutical ingredient Active
    pharmaceutical ingredients (API) are the active
    ingredients in medications, carried by the
    excipient. In each case, the drug has an API and
    it has a trade name, by which it is known in the
    market. For instance, Revlimid is the brand or
    trade name, whereas lenalidomide is its
    API.Therapy segment We have classified drugs
    into five
  • major therapy segments - Targeted, Chemo,
    Hormone,
  • Vaccines and Adjuvants. For instance, Herceptin
    is a
  • Targeted Therapy drug whereas Zytiga is a Hormone
  • Therapy drug.

6
  • Immuno-oncology This is a growing area of cancer
    therapy. We have highlighted whether the drugs
    classified fall under this category or not. For
    instance, Opdivo is an immuno-oncology
    drug.Class of drug Various therapy segments are
    further classified into classes of drugs.
    Monoclonal antibodies, tyrosine kinase and
    alkylating agent are examples of classes of
    drugs. Yervoy is a monoclonal antibody whereas
  • Tarceva is a tyrosine kinase inhibitor.

7
  • Molecule type Drugs are classified into two
    categories,
  • small and large, on the basis of their molecular
    weight
  • greater than 900 daltons are large molecules and
    less than
  • 900 daltons are small molecules. Large molecules
    are
  • also known as biological drugs.
  •  
  • Dosage form We have explained whether the dosage
    is in
  • the form of vials/injections (injectable) or
    tablets/capsules
  • (oral). For instance, Tecentriq is an injectable
    drug whereas
  • Thalomid is an oral tablet.

8
  • Route of administration We have explained
    whether the drug is taken orally or through the
    intravenous route. For instance, Empliciti (for
    multiple myeloma) is taken through the
    intravenous route.Mechanism of action The term
    mechanism of action refers to the specific
    biochemical interaction through which a drug
    substance
  • produces its pharmacological effect. A mechanism
    of
  • action usually includes mention of the specific
    molecular
  • targets to which the drug binds, such as an
    enzyme
  • or receptor.

9
  • First approved indication in the geographies US,
    EU and Japan Many cancer drugs are often
    approved for more than one indication. We have
    highlighted the first approved indication of each
    drug in the various geographies. For instance,
    Xeloda was first approved for metastatic breast
    cancer in the US and Japan whereas, in Europe,
  • it was first approved for colorectal cancer.

10
Full Report Oncology Cancer Drugs Market
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