Paget’s disease : causes, symptoms, diagnosis and treatment

1
Pagets Disease

• CAUSES SYMPTOMS TREATMENT

2
INTRODUCTION TO PAGETS DISEASE

• Paget's disease can affect any bone in the
  skeleton.
• It appears most of ten in the spine, pelvis, long
  bones of the limbs, and skull
• It can be present in just one bone or in several
  bones
• It can affect the entire bone or just part of it.
• Three phases of Paget disease have been
  described lytic, mixed lytics blastic, and
  sclerotic.

3
CAUSES OF PAGETS DISEASE

• The exact cause of Pagets disease is still
  unknown. Some of the believed causes of Pagets
  disease are Genetic mutations
• Measles virus attacks
• Osteoclast cells malfunction
• Environmental factors
• Resorption of bone cells

4
SYMPTOMS OF PAGETS DISEASE

• Bone pain
• Articular or neutogenic pain
• Preparation for orthopedic surgery
• Hypercalcemia associated with immobilization
• Prevention of further hearing loss in patients
  with cranial involvement
• Prevention of further deromity in patients with
  cranial, jaw, spinal or extremity disease
• Reversal of osteolytic lesions
• Prevention of skeletal deformities
• Prevention of arthritis
• Prevention of neurological complication

5
DIAGNOSIS OF PAGETS DISEASE

• CT (Computerized Tomography) - It is a technique
  in which several X-rays are taken from a
  different angle and combined later to make
  detailed images of the affected bones.
• MRI (Magnetic Resource Imaging) - It is an
  imaging test in which high frequency magnetic and
  radio waves are used to get detailed images of
  the affected bones.
• Bone scan - It involves the use of a small amount
  of radioactive solution, known as a tracer. This
  tracer is injected into the patients vein. A
  special camera is used to take pictures of areas
  that absorbed tracer.

6
TREATMENT FOR PAGETS DISEASE

• There is no permanent cure for Pagets disease
  its treatment can only help in the reduction of
  symptoms. Possible treatment of Pagets disease
  is
• Medicines such as, acetaminophen and
  bisphosphonates provide relief from the pain,
  prevent bone loss, and control level of calcium
  in the body.
• Physical therapy, routinely exercise and certain
  vitamin D supplements prevent the Pagets disease
  from developing further.
• In particular cases an osteotomy procedure is
  performed. Osteotomy is a surgical procedure in
  which a segment of bone is removed to correct a
  misalignment.

7
CONNECT WITH US

• Logon to
• www.lazoi.com
• Like us on facebook
• https//www.facebook.com/LazoiTheLife
• Follow us on Twitter
• https//twitter.com/lazoithelife Follow us on
  Pinterest
• https//in.pinterest.com/lazoithelife/