Robert koch

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Robert Koch (1843-1910)
Robert Koch was born on December 11,1843 in
Germany. He popularly called as founder of
modern techniques.
His contribution to microbiology are enormous.
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In 1876-
Robert Koch have successfully isolated anthrax
bacillus in pure culture, studied formation and
germination of its spores and provided a proof of
its infectiousness. In 1877-
Robert Koch have introduced the method of making
smears of bacteria on glass slides, and of
staining them with anilin dye.
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In 1878-
He explored the role of animal experimentation in
establishing the cause of bacterial infections.
In 1881-
He described means of cultivating bacteria on
solid media. He also develop pour plate method.
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In 1882-
He discoveredtubercle bacillus (mycobacterium
tuberculosis), causative agent of tuberculosis,
which was also called as Kochs bacillus. He
described a special staining method for detection
of this microorganism.
In 1883-
He discovered causative agent of cholera(Vibrio
cholaerae), Egyptian ophthalmia (pink eye) and
Kochs weak bacillus.
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In 1884-
Koch expounded the postulates or laws by which an
organism may be proved to be the cause of
particular disease. These were known as Kochs
postulated.

Kochs postulaates-

• The bacterium should be constantly associated
  with lesions of the disease.
• It should be possible to isolate the bacterium in
  pure culture into suitable laboratory animals
  should reproduce lesions to the disecases.
• It should be possible to re-isolate the bacterium
  in the pure culture from the lesion produced in
  experimental animals.

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He also discovered tubercilin.
In 1885-
He showed how a normal guinea pig and an
already infected guinea pigbehaved differently
To an infection withtubercle bacillus. This is
known as Kochs phenomenon.
In 1890-
Koch studied various Micro-organisms Present in
water, soil, and air and their relation in
prevention of diseases.
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• Koch invented-

• Hot air oven,
• Steam sterilizer,
• Basic tools in any microbiology laboratory.

• Koch developed-

• Method of testing antiseptics.
• Method to distinguish bacteriostatic and
  bactericidal concentration.

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Thank you