Neurodegenerative Disorder: Alzheimer’s Disease | Symptoms, Risk Factors

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Neurodegenerative Disorder Alzheimer's disease

• - Specialty Care Clinics

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Neurodegenerative Disorder Alzheimer's disease

• Alzheimers disease is a mental decline that
  interferes with a persons daily life, which is
  not a normal part of aging. Alzheimers is the
  most common cause of dementia. In 2020,
  approximately 5.8 million Americans are living
  with Alzheimers disease. Though it is rare
  younger people may also get affected by
  Alzheimers disease.
• Alzheimer's is a progressive neurologic disorder
  that results in the brain shrinking (atrophy) and
  brain cells dying. Alzheimer's disease causes a
  continuous decline in thinking, behavioral and
  social skills that affect a person's ability to
  function independently.
• People with Alzheimers experience forgetting
  recent events or conversations in their initial
  stage. But, as the disease progresses they would
  develop severe memory impairment and lose the
  ability to carry out everyday tasks.

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What Leads to Alzheimers disease?

• Researchers are trying to understand the exact
  causes of Alzheimer's disease. The brain proteins
  fail to function normally at the basic level,
  which disrupts the work of brain cells or neurons
  and triggers a series of toxic events.
  Eventually, the neurons are damaged and lose
  connections to each other resulting in them to
  die.
• For most people, Alzheimer's disease is caused by
  a combination of genetic, lifestyle, and
  environmental factors that affect the brain over
  time. Rarely, Alzheimer's is caused by specific
  genetic changes that usually occur in middle age.
• The damage often initiates in the region of the
  brain that controls memory, but the process
  begins years before the first symptoms. The loss
  of neurons spreads in an approximately
  predictable manner to other regions of the brain.
  As the disease progresses by the late stage of
  the disease, the brain has shrunk significantly.

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Cause Of Alzheimer's Disease 

• The cause of Alzheimer's disease has been found
  to be focused on the role of two proteins
• Plaques The beta-amyloid (larger proteins)
  fragments cluster together that appears to have a
  toxic effect on neurons. This would also disrupt
  cell-to-cell communication as these clusters form
  larger deposits called amyloid plaques, which
  also include other cellular debris.
• Tangles Tau proteins play a vital role in a
  neuron's internal support and transport system to
  carry nutrients as well as other essential
  materials. The tau proteins in Alzheimers change
  shape and organize themselves into structures
  called neurofibrillary tangles. These tangles
  will disrupt the transport system and are toxic
  to cells.
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