Contrast Enhanced Ultrasound Market: Key Trends & Future Prospects

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Contrast Enhanced Ultrasound Market Key Trends
Future Prospects Contrast enhanced ultrasound
(CEUS) entails the application of ultrasound
contrast medium to conventional medical
sonography. According to Inkwood Research, the
global contrast enhanced ultrasound market is
projected to rise with a CAGR of 5.25 during the
forecast period of 2022 to 2030. The market
growth is attributable to key factors such as the
surging prevalence of chronic diseases as well as
the technological advancements in
diagnosis. Ultrasound contrast agents primarily
depend on the different ways in which sound waves
are reflected between substances from interfaces.
This may either be the surface of a small air
bubble or a more multifaceted and complex
structure. Over recent years, the increasing use
of contrast enhanced ultrasound, and its
extensive use in clinical practice has proven to
be a significant breakthrough in the field of
diagnostic ultrasound. In this regard, CEUS is
used to depict the targeted organs micro- and
macro-circulation, subsequently resulting in
enhanced performance and accuracy in analysis.
Moreover, healthcare providers may also use
contrast enhanced ultrasound in addition to or
instead of other medical imaging tests, such as
magnetic resonance imaging (MRI) and computed
tomography (CT) scans.

• Diagnostic Use of Contrast Enhanced Ultrasound
• Liver Imaging
• Owing to the unique dual blood supply system in
  the liver, contrast enhanced ultrasound is
  predominantly suitable for liver imaging. CEUS
  facilitates the characterization of focal liver
  lesions

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• (FLLs), guidance for interventional procedures,
  detection of liver malignancy, and assessment of
  treatment response following local therapies.
• In patients with known cancerous conditions,
  including high and low malignancy, further
  investigations are often required to definitely
  exclude malignancy. Moreover, the response
  evaluation is a novel challenge, with a research
  focus on the variation in tumor vasculature as
  well as perfusion. CEUS can identify viable and
  necrotic areas of tumors, thus enhancing
  diagnostic accuracy, especially while planning
  biopsies.
• Key companies operating in the contrast enhanced
  ultrasound market are also enhancing their
  presence in the avenue of liver imaging through
  frequent launches of products with upgraded
  functions. For example, Acuson Juniper 2.02 by
  Siemens Healthineers AG is an ultrasound system
  equipped with liver elastography and contrast
  enhanced ultrasound that plays a pivotal role in
  delivering a comprehensive liver evaluation.
• Non-Liver Use
• While the advent of CEUS improves the use of
  ultrasound in the liver for tumor diagnosis and
  guidance, it also offers solutions in numerous
  non-liver organs, such as the kidneys, pancreas,
  gallbladder, heart, and spleen. Furthermore,
  contrast enhanced ultrasounds use has also
  expanded to the bile duct in recent years, with
  promising results. Aligning with this, CEUS is
  particularly useful in the diagnosis of bile duct
  malignancy, including intrahepatic, hilar, as
  well as extrahepatic bile ducts.
• Contrast Enhanced Ultrasound (CEUS) in Drug
  Gene Delivery Key Trend
• In addition to diagnostic applications, contrast
  enhanced ultrasound imaging is presently being
  explored for therapeutic purposes such as
  targeted drug delivery into thrombi and arterial
  walls. One studied application for targeted drug
  therapy entails chemotherapeutic drug delivery.
  In theory, it must focus on drug exposure to the
  local tumor and restrict exposure of healthy
  tissue to the toxic drugs, thus minimizing
  detrimental side effects.
• Microbubbles comprising common anticancer drugs
  in the hydrophilic core circulate into the
  microvasculature of the tumor. At that point,
  ultrasound pulses are used to burst them,
  releasing the drug and also inducing
  sonoporation. As a result, subsequent tumor cell
  death has been demonstrated in vivo and in vitro
  as well.
• Microbubbles can also be used for targeted gene
  delivery. For instance, the bubbles may be filled
  with small interfering RNA, which can
  downregulate transcription factors for cell
  proliferation. These include activators of
  transcription 3 and signal transducer, resulting
  in decreasing tumor burden.
• On the other hand, microbubbles are being studied
  for the augmentation of sonothrombolysis.
  Characterized as a relatively non-invasive method
  of dissolving thrombus, it helps restore blood
  flow through the use of ultrasound energy.
• Contribution of Leading Players
• NanoPET Pharma GmbH Viscover PolySon H/L are
  hard-shell ultrasound microbubbles optimized for
  organ perfusion measurements as well as the
  visualization of the liver and spleen. Moreover,
  based on inducible bubble rupture, they are also
  suited for stimulated acoustic emission imaging
  (SAE).

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• Lantheus Medical Imaging Inc DEFINITY is an
  injectable cardiovascular ultrasound enhancement
  agent utilized in contrast enhanced ultrasound
  imaging. It is composed of lipid-coated echogenic
  microbubbles with octa-fluoro propane gas.
  Administering DEFINITY improves clinicians view
  of the hearts left ventricle during an
  echocardiogram in order to aid diagnosis.
• Contrast Enhanced Ultrasound (CEUS) Market
  Future Prospects
• In various developed as well as developing
  nations, ambulatory diagnostic centers are an
  emerging trend in terms of the provision of
  medical imaging services. On account of its key
  advantages, such as affordability, diagnostic
  effectiveness, portability, and wider clinical
  use, ultrasound is one of the chief tools used in
  conjunction with mobile units. Accordingly, the
  ambulatory diagnostic centers segment, under the
  end-user category, is expected to grow with the
  highest CAGR of 6.66 during the forecast period.
• Since ultrasound contrast agents (UCA) can be
  used as a tracer of blood flow, CEUS can help
  detect hematomas and bleeding sites in patients
  with abdominal injuries, thus surging their
  applications in the field of blunt abdominal
  trauma. Deemed useful for monitoring patients
  undergoing conservative treatment, the technique
  can also assess vascular lesions and active
  bleeding, while avoiding exposure to ionizing
  radiation.
• The advent of contrast enhanced ultrasound has
  significantly improved the expediency of
  ultrasound, and even elevated its position in
  clinical practice. As research and development
  continue to progress in CEUS, new emerging
  technological advancements will further pave the
  way for more economic, reliable, and safe
  diagnoses of various diseases. Consequently, this
  factor is set to play an integral role in fueling
  the global contrast enhanced ultrasound market
  growth during the forecast period.
• Frequently Asked Questions (FAQs)
• What is a contrast agent?
• A A contrast agent is characterized as a
  substance used to intensify the contrast of
  fluids or structures within the body in medical
  imaging.
• What are the two main types of contrast enhanced
  ultrasound analyzed in the report? A Targeted
  and non-targeted are the two main types of
  contrast enhanced ultrasound analyzed in the
  report.
• What is the main advantage of microbubbles?
• A Microbubbles are presently the only clinically
  approved ultrasound contrast agent. Their key
  advantage is that they remain intravascular owing
  to their size, thus facilitating diagnostic
  measurements that would otherwise be challenging
  with diffusible tracers.