The New Frontier: Gene Therapy

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The New Frontier Gene Therapy
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Germline and somatic gene therapy
Consider also what kinds of genetic diseases
could be treated
Fig. 7.1
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Construction and packaging of a retroviral gene
therapy vehicle
Like 7-3
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Adenovirus and adeno-associated virus-mediated
gene transfer
Fig. 7.4
Fig 7.5
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Liposome/lipoplex-mediated gene delivery
not in text
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Gene therapy for Cystic fibrosis Duchenne
muscular dystrophy Haemophilia SCIDS ADA
deficiency
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Gene therapy to treat severe combined
immunodeficiency disease (SCID)
not in text
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In vivo gene therapy for brain tumors
like 7-6
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Increasing MDR expression in blood stem cells to
fight cancer