Community Pharmacists Monitoring of Pulmonary Tuberculosis Outpatients Preliminary Study

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(No Transcript)
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Community Pharmacists Monitoring of Pulmonary
Tuberculosis Outpatients (Preliminary Study)
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Authors
Usasiri Srisakul, M.Sc. in Pharm (Clinical
Pharmacy) Phayom Sookaneknun, PharmD Sunantha
Osiri, Ph.D Institution Faculty of
Pharmacy and Health Sciences, Mahasarakham
University, Thailand, 44150 Study funded by
Health Systems Research Institute
(HSRI), Thailand
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Introduction

• DOTS (Directly Observed Treatment, Short Course)
  for pulmonary tuberculosis (PulTB) is a major
  strategy in the National Tuberculosis Programme
  (NTP) following WHO global plan.
• Thailand ranked the 16th in 22 high-burden
  countries.

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Objectives

• To compare clinical outcome between
• Community pharmacists monitoring patients
• Control patients receiving normal care

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Method

• Quasi experimental study design
• Patients
• Pulmonary Tuberculosis (PulTB) without HIV
  co-infection
• DOT category 1 (2HRZE 4HR)
• December 2002 January 2004
• Mahasarakham provincial hospital
• Preliminary study
• December 2002 October 2003
• N 54

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PulTB with DOT category1 N54
Completed intensive treatment phase
2nd month
Volunteered
Community pharmacists monitoring group N27
Control group N27
3rd 5th month
Clinical outcomes
6th month
Figure 1 Research procedure
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Method (cont.)

• Community Pharmacists monitoring group
• Refill of DOTS medication (1-4 weekly follow up)
• Pharmaceutical care
• Control group
• Normal care from the hospital (1-3 monthly follow
  up)
• Clinical outcomes
• Cure rate
• Treatment success rate
• Default rate
• Failure rate

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Results Demographic data
No significant differences in all demographic
data betweent both groups.
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Results Clinical outcomes
Significant differences
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Results Clinical outcomes
0.022
0.054
0.043
0.313
Figure 2 Clinical outcomes
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Discussion

• Community pharmacist monitoring can improve
  treatment succes rate (WHO goal gt 85), decrease
  default and failure rate
• Show the community pharmacist involvement in DOTS
  multidisciplinary team
• In the future study should be expanded number of
  patients, community pharmacy setting and referral
  system

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Conclusion

• Community pharmacist involvement in a DOTS
  multidisciplinary team improved clinical outcomes
  in pulmonary tuberculosis outpatients.

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Thank you very much