Singlestranded DNA, nonenveloped viruses

1
Single-stranded DNA, nonenveloped viruses

• Parvoviridae
• Human parvovirus
• Fifth disease
• Anemia in immunocompromised patients

2
Double-stranded DNA, nonenveloped viruses

• Mastadenovirus
• Respiratory infections in humans
• Tumors in animals

3
Double-stranded DNA, nonenveloped viruses

• named for papillomas (warts), polyomas (tumors),
  and vacuolation (cytoplasmic vacuoles)
• Papillomavirus
• human wart virus
• one of the leading STDs in the U.S.

4
Double-stranded DNA, nonenveloped viruses

• Cause diseases involving skin lesions
• Pox refers to pus-filled lesions
• Orthopoxvirus
• smallpox (variola) virus
• Molluscipoxvirus
• molluscum contagiosum, cowpox

5
Double-stranded DNA, nonenveloped viruses

• named for the spreading (herpetic) appearance of
  sores
• Simplexviruses (HHV-1 2)
• cold sores and genital herpes
• Varicellavirus (HHV-3)
• chickenpox
• Lympocryptovirus (HHV-4)
• infectious mononucleosis
• Roseolovirus (HHV-6)
• roseola
• (HHV-8)
• Kaposis sarcoma, in AIDS patients
• Some can remain latent

6
Double-stranded DNA, nonenveloped viruses

• Hepadnavirus
• Hepatitis B virus
• Use reverse transcriptase to produce DNA from
  mRNA
• oncovirus

7
Single-stranded RNA, strand, nonenveloped

• Smallest viruses, the prefix pico means small
• Enterovirus
• 70 known Enteroviruses including the poliovirus
• Rhinovirus
• More than 100 exist
• Most common cause of colds
• Hepatitis A virus

8
Single-stranded RNA, strand, nonenveloped

• Hepatitis E virus
• Norovirus
• causes gastroenteritis

9
Single-stranded RNA, strand, nonenveloped

• Arbovirus
• functional grouping
• replicate in arthropods
• Alphavirus
• include EEE, WEE viruses
• Rubivirus
• rubella
• Transmitted by respiratory route

10
Single-stranded RNA, strand, nonenveloped

• Arbovirus
• Flavivirus
• West Nile virus
• Hepatitis C caused by at least 2 unclassified RNA
  viruses 1 may be a Flavivirus
• Yellow fever virus
• Dengue fever virus

11
Single-stranded RNA, strand, nonenveloped

• Coronavirus
• Upper respiratory infections and the common cold
• SARS virus

12
Single-stranded RNA, strand, one RNA strand

• Bullet shaped with spiked envelope
• Lyssavirus
• rabies virus
• Cause numerous other animal diseases

13
Single-stranded RNA, strand, one RNA strand

• Filovirus
• Enveloped, helical viruses
• Ebola and Marburg viruses

14
Single-stranded RNA, strand, one RNA strand

• Paramyxovirus
• parainfluenza and mumps
• Morbillivirus
• Measles-like virus

15
Single-stranded RNA, strand, one RNA strand

• Hepatitis D virus
• Depends on coinfection with Hepadnavirus
  (hepatitis B)

16
Single-stranded RNA, strand, multiple RNA
strands

• Influenzavirus
• Influenza viruses A, B and C
• Envelope spikes can agglutinate RBCs

17
Single-stranded RNA, strand, multiple RNA
strands

• Bunyavirus
• California Encephalitis virus
• Hantavirus
• Pulmonary syndrome associated with rodents and
  hemorrhagic fevers

18
Single-stranded RNA, strand, multiple RNA
strands

• Arenavirus
• Helical capsids contain RNA-containing granules
• Lassa Fever

19
Single-stranded RNA, two RNA strands, produce DNA

• Lentivirus
• Human Immunodeficiency Virus
• Use reverse transcriptase to produce DNA from
  viral genome
• Oncovirus
• Includes all RNA tumor viruses

20
Double-stranded RNA, nonenveloped

• Reovirus
• Mild respiratory infections
• Rotavirus
• gastroenteritis