Pulmonary Pathology II Case 5

1
Pulmonary Pathology IICase 5

• 71 year-old man with back pain, hepatomegaly, and
  enlarged hilar lymph nodes.

2
Identify the organ Describe the gross morphologic
changes Diagnosis?
3
Bronchogenic carcinoma The right lung is bisected
into an anterior half (A) and a posterior half
(B). The white neoplasm occupies most of the
lower lobe and extends into upper lobe. The
neoplasm obstructs the right mainstem bronchus.
Peribronchial lymph nodes (arrow) contain
neoplasm.  
4
Describe the microscopic findings
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Neoplasm is composed of small cells containing
dark blue, round nuclei and sparse cytoplasm.
These cells resemble (but are not) lymphocytes
and are arranged in clusters
6
Identify the organ Describe the gross morphologic
changes Diagnosis?
7
Metastatic Carcinoma Liver parenchyma (cut
surface) largely replaced by metastastic
carcinoma (yellow arrow)