The PPAR Journey: What Can We Expect in the Future?

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The PPAR Journey What Can We Expect in the
Future?
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Targets of Glucose-Lowering Drugs
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PPAR-a and PPAR-g Agonists Target Systems
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Effects of Fibrates on Cardiovascular Events A
Systematic Review and Meta-Analysis
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CV Events With PPAR-g Agonists
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Expected Targets for Dual PPAR-a/g Agonists
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Dual PPAR a/g Agonists
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GALLANT 8 Effect of Tesaglitazar on Top of
Metformin vs Metformin Alone on HbA1c
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GLAD Effect of Tesaglitazar vs Pioglitazone on
Lipid Measures
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Tesaglitazar Effect on Serum Creatinine and
Glomerular Filtration
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Dual a/g PPAR Agonist Effect of Muraglitazar on
Metabolic Parameters
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Effect of Muraglitazar on CV Outcomes
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SYNCHRONY Effect of Aleglitazar on
Cardiometabolic Parameters in T2D
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SYNCHRONY Cardiovascular Safety
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SYNCHRONY Effect of Aleglitazar on Markers of
Renal Function
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SESTA R Impact of Supratherapeutic Doses of
Aleglitazar on Renal Function in T2D
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ALENEPHRO Objective and Study Design
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Summary PPAR Therapy
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Abbreviations
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Abbreviations (cont)
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References
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References (cont)
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References (cont)
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References (cont)