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Name some famous serial killers?

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Title: BIOTERRORISM & CHEMICAL WARFARE and the Role of the Pharmacist Author: Frank Paloucek Last modified by: Created Date: 10/16/2001 1:59:35 AM – PowerPoint PPT presentation

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Title: Name some famous serial killers?


1
Name some famous serial killers?
  • Jack the Ripper
  • Jeffrey Dahmer
  • John Wayne Gacy
  • Ted Bundy

2
Do You Know?
  • Jack the Ripper (7)
  • Jeffrey Dahmer (31)
  • John Wayne Gacy (33)
  • Ted Bundy (20)

3
Harold Shipman, M.D.
4
Graph showing death rates by physicians
5
Why dont we know these names?
  • Harold Shipman, MD
  • Michael Swango, MD
  • Michel Pettiot, MD (63 murders in 1940s)
  • John Adams, MD (40 murders in 1950s)
  • Orville Majors, Donald Harvey, Genene Jones,

6
First Exposure
  • 22 y/o mother of 4 transferred after 19 days at
    another hospital
  • Initially, 2 week N/V/D, cough, rash, weakness.
  • Was pancytopenic, pneumonia ascending peripheral
    paralysis
  • Day18 seizure and ventricular fibrillation
    (Torsades de pointe)
  • Multiple episodes VF, /- response to lidocaine
    and Mg2.
  • Neuropathy worse

7
Case continued
  • Neuropathy worse, needs ventilator to breath
  • D 54, family priest comes in with story of
    confession about arsenic-laden OJ given to
    patient at party.
  • Testing yielded normal urine but severely
    elevated hair levels in a pattern that suggested
    acute-on-chronic exposure
  • 1984 - while a resident on Dr. Baumans
    cardiology rotation.

8
CHICAGOS POISONING HISTORY
  • Johann Hoch - The Stockyards Bluebeard
  • 1892-1905 murdered 12 of 24 wives with arsenic.
    Collected assets. Hanged 2/23/1906
  • HH Holmes
  • Dr Holmes built a drugstore empire based in
    SouthSide of Chicago. Remains of gt 200 people
    found in his castle. Spree lasted from 1893-1896.
    Considered the first sensational crime trial in
    American crime history
  • The devil and the White City
  • Tille Gburek
  • Chicago psychic, known for predicting exact
    date of 5 husbands and 3 neighbors deaths -
    arsenic

9
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10
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11
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12
MODERN CHICAGO
  • Tylenol murders
  • 9/29-10/1/82, seven deaths from cyanide-laden
    Tylenol capsules
  • Never solved, appears purely random act of
    poisoning
  • After publicity of case, following month had 270
    reports of product tampering, 36 were proven true
    in the U.S.
  • Lead to development of two innovations
  • Dosage form?
  • Packaging?

13
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14
CHICAGO Summer 2002
  • July- 12 y/o severe Cerebral palsy, non-diabetic,
    found unresponsive by family member (no family
    member was diabetic, EMT found glucose 0
  • Multiple D50Ws and dextrose infusions over next
    16 hours to maintain glucose of 40-60
  • Blood insulin 400 (20 x nl), no c-peptide
  • 9/9/02 67 ovarian cancer with mets, presents
    with A fib. Admitted to CICU. Digoxin 0.25 iv
    ordered, 2.5 mg given experienced RN (?)

15
ILLINOIS HISTORY
  • Michael Swango (30) 00-Swango
  • Born 1974 Quincy
  • Medical school at SIU didnt graduate
  • 1984 Quincy paramedic - co-workers always got
    sick when he brought doughnuts, soda, iced tea
    (Ant poison Arsenic found mixed with sugar in
    home. Charged and convicted aggravated battery 5
    yrs prison.
  • Lied about graduation and licensure, worked in
    hospitals in 5 states (inc Harvard) and Zimbabwe.
    Always large number of deaths noted during his
    duty
  • Blind Eye by James B. Stewart

16
Toxicomaniacs
  • Michael Swango
  • Helene Jegado 1800s (23)
  • arsenic to families she worked as maid for.
  • Jane Toppan (31)
  • Boston 1840s, private nurse with special
    cocktails except too many died
  • Graham Young
  • 1980s. 2 deaths, many poisonings, many
    compounds.On arrest enough poison to killgt 300 in
    home
  • Young Poisoners Handbook movie

17
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18
Mercy Killers
  • Nurses
  • K Gilbert (4) 96-7 NC epinephrine
  • Richard Diaz (12) CA succinylcholine
  • Orville Majors (70-130) 1993-5 Indiana epi, KCL
  • Don Harvey (37-80) 1970-1987,
  • Edson Guimares (5-131) Sao Paulo RN tech KCL, C
    Malevre (4-30 Paris 1997-8) Queen of euthanasia,
    W. Wagner gang Austria (45-200) 1983 MSO4/water
  • Others
  • E Saldivar resp therapist (50) Glendale
    1989-1997pancuronuim,
  • A Nessitt nursing home administrator Norway 22
    curare
  • Midwife (36 women) gang, Hungary (80-300 men)
    1914-1929 arsenic

19
U.S. Mercy Killers 1980-1990s
  • Nurses, alone or in groups, arrested for 172-240
    suspicious deaths in 7 U.S. hospitals during
    1980s
  • 4 Nurses arrested for 123-195 deaths in 1990s in
    4 U.S. hospitals
  • Kevorkian? , Philip Nitschke? (Aussie), Christine
    Malevre (French)?

20
Mercy Killers 2000s
  • Hungarian Nurse (Black Angel) 30-40
  • Dutch nurse 14 deaths mostly elderly or vry
    young children, avidly read biographies on serial
    killers
  • Japanese nurse 10 deaths in his care, all
    children (vecuronium)
  • Nurse, Texas arrested 7/2002 for 15 deaths 11
    days mivacurium
  • West Palm Beach nurse used propofol, charged with
    1 death. Investigating others

21
Extortion
  • Usually isolated poisoning, product tampering
    with lawsuit against manufacturer desired result.
  • Australia 1999 - Dennis Donald Fountain arrested
    for lacing strychnine into tampering OTC
    painkillers, three people hospitalized.
  • Companies pulled product off shelves, est 72 M
    lost revenue
  • Then threatened two manufacturers he would use
    their product next for 1 M in cash

22
Pharmacist Poisoners?
  • No known current (at least to me)
  • Closest thing to it The non-Poison killer,
    Robert Courtney
  • Kansas City MO, pharmacist caught by sales
    representative who was reviewing billing ordering
    records for chemotherapy
  • He was diluting products Gemzar and Taxol

23
Nanjing China
  • At least 40 dead (up to 100)
  • Breakfast shop serving middle school kids and
    migrant workers
  • Rival shop owner contaminated food with tetramine
    (banned rodenticide since 1991)
  • At least 150 dead over past 12 months in similar
    events

24
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25
CURRY POISONINGS
  • 1998 - 4 deaths and 63 ill after eating food at
    picnic. Arsenic found in curry.
  • Two years to find suspect
  • In interim over 40 copycat poisonings and product
    tampering events in same year.
  • Cyanide laced Coke, disinfectant
  • Repetitions (poison pizza) continue in Japan

26
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27
Curry Poisoning (cont)
  • Masumi Hayashi 37 y/o insurance saleswoman
    married to fumigator husband arrested.
  • Had sold insurance policies to festival
    attendees, average 11 k.
  • Tip was from visitor who got ill after signing
    policy in her home and being given drink and food
    that immediately made him ill

28
Current Food Poisoning (cont)
  • 3 arrested in Jerusalem September 2002 for
    plotting to poison customers in Café where they
    worked, targeted pitchers of Coke
  • 60 grade school children Joliet Illinois
    hospitalized for food poisoning from eating
    chicken tenders
  • Ammonia spill in meat packing plant, product
    already packaged, decided okay to still use but
    sprayed with pesticide first

29
Conclusions
  • Malicious poisoning far more common and deadly
    than casual perception
  • Healthcare professionals who poison are
    frequently identified by casual epidemiology or
    coworker concerns
  • Unusual death rates and or discrepancies in
    stocks for KCL, paralytics, cardiac meds should
    be compared to deaths and work shifts
  • Easiest to catch within the in-patient acute care

30
Harold Shipman, M.D.
31
Major internet sites
  • Mayhem.net
  • Crimelibrary.com
  • Karisable.com
  • Cybersleuths.com

32
Now this is bioterrorism!
33
  • Paloucek_at_uic.edu
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