Proportion of patients with serum urate levels of <6.0 mg/dL

1
Proportion of patients with serum urate levels of
lt6.0 mg/dL
Treatment, (n) Treatment, (n) Treatment, (n) Treatment, (n) Treatment, (n)
Serum urate levels of lt6.0 mg/dL Febuxostat 80 mg Febuxostat 120 mg Febuxostat 240 mg Allopurinol 100 or 300 mg Placebo
Primary end point sUL at last 3 visits 48 (126/262) 65 (175/269) 69 (92/134) 22 (60/268) 0 (0/134)
sUL at week 28 76 (122/161) 87 (163/188) 94 (78/83) 41 (85/208) 1 (1/99)
sULserum urate level
Schumacher HR et al. ACR/ARHP Annual Scientific
Meeting November 13-16, 2005 San Diego, CA.
APEX study shows efficacy of febuxostat in
hyperuricemia and gout Rheumawire gt News Nov
30, 2005