Warm-Up

1

• Warm-Up
• Write your homework get it stamped!
• Update your table of contents for today!
• Complete the Before column ONLY on the
  Anticipation Guide on the front counter and tape
  it on to page 14!

Date Session Activity Page
1/22 1/26 7 Anticipation Guide Background Notes 14
MilkHow Sweet Is It? Lab Guide 15

2

• Warm-Up
• What were your answers on the Anticipation
  Guide?
• What do you think coevolution is?
• Starting with the next slide, whatever is in
  black are the notes you should be writing!

3

• Coevolution
• Coevolution when 2 (or more) organisms or
  things affect each others evolution/evolve
  together dependent on each other

4

• Lactose Vs. Lactase Notes
• Lactose a sugar found only in milk
• Lactase an enzyme found in the lining of the
  small intestine that breaks lactose down into
  glucose, which can be digested by the body
• Just FYI
• Enzyme a substance produced by a living
  organism that acts as a catalyst to bring about a
  specific biochemical reaction

5

• Lactose Vs. Lactase
• What does lactose intolerance mean?
• So what do you think lactase persistence means?
• These are genetic characteristicsso, do you
  think that it is more likely for people to be
  lactose intolerant or lactase persistent?

6
The Facts About Lactose IntoleranceRemember,
Milk has Sugar, Fats Proteins!

• Lactose intolerant people cannot digest the
  sugar (lactose) in milk because they do not
  create enough of the lactase enzyme.
• Because the milk races through the digestive
  system very little of the other nutrients (fats
  proteins) can be absorbed

7
Milk How Sweet Is It? Lab

• Your group will have a sample of the intestinal
  fluid of a patient. You will test the fluid to
  determine if your patient has the gene for
  lactase persistence and is able to digest milk.
• Follow the lab directions and share your data
  with the class by adding your data to the table
  on the board.
• Answer the lab questions on your sheet.

8
Milk How Sweet Is It? Lab Roles

• Group Leader reads all directions and keeps
  group on task reinforces the jobs of others
• Supply Manager/Clean Up manages supplies
  cleans up after both parts of the lab are
  complete
• Math Map Master does calculations is in
  charge of recording math map information
  (someone with a phone an agenda to use the map
  in the front of it)
• Discussion Leader Leads the discussion of the
  questions to share information with the group and
  the class if required

9
Milk How Sweet Is It? Lab Results
  2 minutes
Samples Glucose levels (mg/dL) Lactose Intolerant or Lactase Persistent?
 Patient 1 (Japan)  
 Patient 2 (Kenya)  
 Patient 3 (China)  
 Patient 4 (Italy)  
 Patient 5 (Papua New Guinea)  
 Patient 6 (Finland)  
 Patient 7 (Saudi Arabia)  
 Patient 8 (Uganda)  
10
Global Distributionof theLactase Persistence
Genotype

• You will analyze the distribution of lactase
  persistence (ability to digest milk) across a
  large area of the world.
• Calculate the frequency of lactase persistence
  for the 3-4 regions on your strip of paper.
• For each region, you must put a sticker on the
  board. If the percentage is less than 40, place
  a pink sticker, if the percentage is equal to or
  greater than 40, place a green sticker.
• 3. When you have the percentages calculated, send
  your Math Map Master to place the stickers on
  the correct country on the map on the board.
•  

lactose intolerance
lactase persistence
11

• 1. Create a key for the map on your answer sheet.
• Green for lactase persistence (ability to digest
  milk 40)
• Red for lactose intolerance (ability to digest
  milk lt 40)
• 2. Using dots or shading, duplicate the class
  data on the map on your note guide.

12
Global Distribution of the Lactase Persistence
Genotype
Answer the activity questions below the map on
your note sheet
13
Got Lactase? The Co-Evolution of Genes Culture

• Got Lactase The Co-Evolution of Genes and
  Culture
• http//www.hhmi.org/biointeractive/making-fittest-
  got-lactase-co-evolution-genes-and-culture
• https//www.youtube.com/watch?vumiLaW5AmKgnoredi
  rect1
• During the video, answer the video questions 1-4
• After the video, go back to the Anticipation
  Guide from your Warm-Up and fill out the After
  column, and then answer question 5.

14
HOMEWORK
Answer the reflection questions on the back of
the note guide by next class!