1. Infectious Bursal Disease

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• 1. Infectious Bursal Disease
• 2. Leukosis and Sarcoma
• 3. Mareks disease
• 4. Avian malaria
• 5. Leucocytozoonosis
• 6. Chicken anemia
• 7. Reovirus infection

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Avian Leukosis and Sarcoma

• ??????????????????????????? ????????????? gt20wk
  ??????????????????????????????????????
  ?????????????? ???????????????????????????????????
  ????????? ???????????????? ??? ??????????????????
  ????????????? ????????
• ?????????? ???? ???? ?????? ???????? ???????

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• ?????????
• 1. Vertical transmission
• 2. Horizontal transmission????????????????????????
  ???? 16-24 wk.
• ?????
• ?????? 1 (Lymphoid Leukosis/Big Liver disease)
• ??? ???????? ???????? ????????????? ??????????????
  ??? ??????????????????? (????????????????)
  ?????????????? ?????????/????, ?????? Mareks
  disease.

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• ?????? 2 (Erythroblastosis)
• ????????? ??????????? ?????????????????????
  cyanosis ?????????? ???????????????????????
  ?????????????????????
• ?????? 3 (Myelocytomatosis)
• ?????????????????????? ???????????????????????
  ???? ??????? ???????? ??
• ?????? 4 (other tumors)

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??????????? (Mareks disease)

• ??????????????????????????????????????????????????
  ????? ??????????????????????????
• ?????????????????, ????? ????????? ???????????
• ?????????
• 1. ?????? ?????? ????? ?????
• ??????? ?????????????????????!
  !!!!
• 2. air borne

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• ?????
• 1. ???????????? ???????????????
  ????????????????????????????????????????? 14 ???
  
• ???????????
• ????????? Thymus ??? Bursa gtgt???????????????????
  ??
• ??????????????????
• ??? ?????
• ????????????????????????????????? ????????
  ????????????????????

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• 2. ??????????? (??????????????????)
• ?????????????? ???????????????????????????????????
  ???
• ??????????????????? 8-9 wk ???? 10-16 wk.
• wbc ?????????????????????????????
• 1. sciatic nerve ?????? (?????) ?????????????????
• 2. vagus nerve ?????? (???????????????????)
  ???????????????????? ??????????

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??????????????????????????????
MDV feather debris
Infection of respiratory tract (day 1)
Infection of lymphoid tissues (day 3-7)
Lymphoreticulitis, Lymphbid atrophy
Immunosuppression (day 7 / day 21)
Productive infection of feather
follicle epithelium (day 5)
Cell-associated viremia (day 5)
Visceral lumphomas (day 14)
Peripheral nerve lesions (day 10) neurolymphomato
sis
Atherosclerosis
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• 3. ??????????/??????????/???????????
• ??????????????????????????????????????????????????
  ????????????????????? ???
• ???????????????????????????????????
  ?????????????????????????????????????????? MD
  ????????
• ??????????????????? ? ????????????????????????????
  ??????????????? ( 6 ???????)
• ????????
• ?????

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????????? ?????????????? ???????????????????????
??????????????????????????????????????????? ??????
??? 6 ??????? ???????????????????????? ?????????
??
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???????????????????????????? ????????????????????
?? Feather follicle ????? ????????????????????????
? ???????????????????????????? ???????????????????
???????????????????? ?????????? ??????????????????
????????????