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Action plan for COST Action 636 WG 4: Analytical issues

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Title: Standardisation and Validation of Analytical Methods Author: fs Last modified by: Anna Ledin Created Date: 2/25/2004 1:34:26 PM Document presentation format – PowerPoint PPT presentation

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Title: Action plan for COST Action 636 WG 4: Analytical issues


1
Action plan for COST Action 636WG 4 Analytical
issues
2
Main objective of COST action 636
  • to assess the role of xenobiotics in the urban
    water cycle and to set up strategies for
    minimising their impact on humans and ecosystems
  • ? need for analytical tools for
  • identification and quantification of xenobiotics
    in the urban water cycle
  • identification and quantification of their impact
    on humans and ecosystems

3
WG 4 Action plan month 1 6 (I)
  • Selection of target compounds (in collaboration
    with other WG)
  • Criteria
  • Occurrence in the urban water cycle throughout
    Europe
  • Occurrence in most of the compartments of the
    urban water cycle in Europe
  • Emerging compounds preferred
  • Sub-criteria toxicity, persistence,
    bioaccumulation
  • Examples
  • Pharmaceuticals (X-ray contrast media,
    lipid-regulators, beta-blockers, NSAID,
    antibiotics)
  • Biocides (Triclosan, Sea nine, BAC)
  • Heavy metals (Cu, Cd, Zn)

4
WG 4 Action plan month 1 6 (II)
  • Selection of target compounds
  • Questionnaire A (target compounds, relevant
    matrices)
  • Month 1 preparation and sending it out to all
    COST 636 participants
  • Month 2 reply of the participants
  • Month 3 evaluation of the data
  • Questionnaire B (analytical methods)
  • Month 4 sending it out to WG 4 participants
  • Month 5 reply of the participants
  • Month 6 evaluation of the data
  • Presentation of results 2nd meeting

5
WG 4 Action plan month 7 12 (I)
  • Interlaboratory study
  • Selection of compounds and matrices according to
    questionnaire results
  • Preconditions
  • No CRM available
  • No commercial provider
  • Preparation of a draft protocol for sampling,
    sample preparation, shipment, storage
  • Examples
  • Pharmaceuticals (NSAID, sulfonamides)
  • Non-agricultural biocides

6
WG 4 Action plan month 7 12 (II)
  • Literature survey on analytical techniques for
    target compounds in different matrices
  • Tasks will be distributed between WG 4
    participants during month 6 meeting
  • Quality control of existing methods described in
    literature
  • Identification of knowledge gaps and research
    needs
  • Outcome could be published in a review article

7
WG 4 Action plan Future topics
  • Advanced analytical technologies (incl.
    biosensors, nanotechnologies, adsorbents)
  • Invite company representatives, additional
    experts
  • Quality control for research laboratories
  • Minimum requirements for publications of
    analytical methods
  • Tools for toxicity evaluation, TIE (together with
    WG 3)
  • Sampling
  • Sum parameters
  • Degradation products (together with WG 2)
  • Analytical methods for identification of sources
    (together with WG 1)
  • Concepts for identification of future emerging
    compounds

8
WG 4 Future meetings
  • April 2006 (Lubljana, Karlsruhe)
  • Selection of target compounds
  • Analytical methods for target compounds in
    different matrices
  • Set-up of interlaboratory study
  • Start of literature search on analytical methods
    (distribution of tasks between participants)
  • September 2006 (Luxembourg)
  • Results of interlaboratory exercise
  • Results of literature survey
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