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Associations of amphipathic molecules in aqueous solutions. Amino acids bear structural similarity to each other Phenylalanine Tyrosine Phenylalanine Leucine ...
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... of temperature, concentration, solvent selectivity, and polymer composition, ... selective solvent (dimethylformamide or dimethylacetamide) into a selective ...
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Membrane Structure and Function Topic 3 Membrane Structure Phospholipid bilayer Amphipathic liquid-crystal properties/behavior allow for constant movement of HC ...
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... like palmitate ion, are amphipathic compounds, ... related carboxylic acid ... nitrogen atom and the nitrogen carries a +1 charge. 10.6: Amines * Naming ...
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Leucine Zipper. amphipathic a-helix like HLH. every 7th aa in helix is Leucine ... leucine zipper (b-zip) activation domains. Activation Domains ...
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Detergents amphipathic/amphiphillic molecules that have a limited solubility ... Turbidity is often measured in simple spectrophotometer ( 300-500nm) ...
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Rat. Human. OATP1B1. OATP1B3. OATP2B1. Hepatocyte ... Rat. Human. Function. Substrates tend to be amphipathic molecules with high molecular weight ( 450) ...
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Lipid- water insoluble organic substance extractable by nonpolar ... Lipid Solubility. Amphipathic- hydrophilic and hydrophobic regions. Possible arrangements ...
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... fats and oils. Waxes moisture ... Essential oils menthol. Fatty acids. Amphipathic molecule. Polar carboxyl group ... Difference between fats and oils ...
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Soaps are sodium or potassium salts of long-chain (12 to 20 carbons) carboxylic ... Soaps solubilize greasy dirt because they are amphipathic that is, they contain ...
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A helical wheel diagram showing the distribution of polar and non-polar residues ... Side-by-side association of four amphipathic helices ...
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The Leucine Zipper Motif. Forms amphipathic alpha helix and a coiled-coil dimer. Leucine zipper proteins dimerize, either as homo- or hetero-dimers ...
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A large number and variety of organic molecules and ions. ... Lipid bilayer. Phosphotidylcholine. amphipathic molecule. Synthetic membranes. Liposomes ...
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Detergents are amphipathic molecules that dissolve most cellular molecules ... Magnification and resolution are distinct properties of microscopes: Fig. A2 ...
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Schematic Representation of the Putative Steps in the Mechanism of ... Amphipathic Helix. Catalytic domain. PC7. 783 (SPC7, LPC, PC7, PC8) D H S. PC4. 654 (SPC5) ...
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Cardiovascular disease 927,448 deaths, about 250,000 more than HIV/AIDS, ... is an amphipathic lipid molecule (i.e. waxy fat) found in every cell in the body ...
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1. primary structure determination (see handout) 2. Draw the ... heptad repeat. g' e' b' f' a' d' c' 'amphipathic' helices. g. f. e. d. c. b. a 'GCN4' ...
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Self-Check Self-Check Lecture 3 Outline (Ch. 7) ... proteins embedded in membrane Membrane structure freeze fracture proteins intact, ...
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Water Properties Lab Water is Polar Covalent Nonpolar Oxygen (even sharing of e-) Uneven sharing of e- Hydrogen Bonds Weak bonds between like molecules p. 3 Cohesion ...
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Introduction to molecular biology of the cell. Haixu Tang. School of Informatics ... as Biochemical Factories Dealing with the Same Basic Molecular Building Blocks ...
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Bionanotechnology Dr Cait MacPhee (cem48@cam.ac.uk) Dr Paul Barker (pdb30@cam.ac.uk) Mondays 12 pm, Tuesdays 11 am
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Title: Hein and Arena Author: M Last modified by: Thao Yang Created Date: 10/20/2003 6:50:10 AM Document presentation format: On-screen Show (4:3) Company
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Chapter 12 Intracellular Compartments and Protein Sorting How all of the 10,000~20,000 kinds of proteins go to the right destination? Intracellular compartments in ...
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Membrane Structure and Function Chapter 7
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Liver Gallbladder Common bile duct Pancreas Pancreatic duct Duodenum Biliary and Pancreatic Anatomy Pancreatic Anatomy Pancreatic Secretions Acinar Enzymes ...
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Hydropathy scale - aa assigned value reflecting. relative phob/phil, based on: ... hydropathy plus helical wheel diagrams. Transmembrane Domains. SOSUI of NPC1 ...
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A nucleic acid consists of four kinds of bases linked to a sugar-phosphate backbone. A monomer unit
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Membrane Structure and Function
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Shortlist - sequences with correct parent mass. Top scoring sequence ... Thousands of sequences shortlisted. Scoring rank. 23/30 peptides identified correctly ...
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Membranes form as a result of noncovalent interactions between ... Kinky structures. Saturated. Flexible structures. 3 molecules of stearic acid (saturated) ...
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Usually comprised of a long chain of a single monosaccharide ... Chitin is the polysaccharide found in insect exoskeletons and crustacean shells. Fatty Acids ...
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Archaeal cell walls Can be gram-positive or gram-negative Gram-positives often have a thick surface layer Gram-negatives often have a thin layer of protein or ...
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... H and acceptor is LESS than van der Waals distance but much more ... Noncovalent Interactions. van der Waals repulsion. Overlap of outer electron clouds ...
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1 Synthesis increased by ATP, NADH, acetyl CoA, citrate, insulin and malonyl CoA. ... Fatty acid chains, and then a head group, much more polar structure.
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Lecture-5 LIPID
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Lipids. Lipids are non-polar (hydrophobic) compounds, soluble ... 18:1 cisD9 oleic acid ( 9) 18:2 cisD9,12 linoleic acid ( 6) 18:3 cisD9,12,15 a-linolenic acid ...
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Melittin (bee venom), magainins (frogs) and cecropin (from cecropia ... amide - frogs - 23 ... Xenopus laevis (African clawed frog) healed without infection, ...
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2 The Composition of Cells BL 424 Ch. 2 Review Composition of Cells Cell biology seeks to understand cellular processes in terms of chemical, physical reactions
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... two hydrocarbon tails give phospholipids a cylindrical shape ... Hydroxyl group constitutes the polar head group. OH is attached to ... the polar head group. ...
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Alzheimer's disease (amyloid plaque) ... There are also deposits of amyloid around many blood vessels. The amyloid weakens the walls of the blood vessels and ...
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ROSETTA. Pioneered by Baker Group (U. of Washington) Fragment ... ROSETTA. Pre-build fragment library. 3-mers and 9-mers. 200 structural possibilities for each ...
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Protein Structure Prediction Sequence database searching Domain assignment Multiple sequence alignment Comparative or homology modeling Secondary structure prediction
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NOVEL DRUG DELIVERY SYSTEMS Introduction Transdermal drug delivery systems These are defined as self-contained, discrete dosage forms which when applied to the ...
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Introduction to Lipids
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Logical consistency. hypothesis 'cause' experiment ' ... conclusion: logical consistency. Cnxns to chem. Cell types. most important concept: All cells have ...
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Involved in cell identity (blood group antigens) Membrane lipids. Cholesterol ... Attached to plasma membrane. Cell wall. Surrounds plant cells. Composed of ...
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Receives signals from outside the cell for internal cellular activities ... Each C=C bond causes a kink or bend in the tail. Can't pack tightly in the layer ...
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Serve as barriers to separate contents of cell from external environment or ... bilayer and hydrophilic regions protruding inside and outside of membrane ...
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Question 1. List the following items in order of size from the smallest to largest: A. Nucleosome smallest__C_____ B. Mitochondrion __A_____
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Protein structural element. Yun-Ru (Ruby) Chen ??? Ph.D. The ... Aliphatic. pKa=13.6. cis-trans Isomerization (trans:cis) Non-proyl (1000:1) X-proyl bond (4:1) ...
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With Antiparallel Helices. Beta-Sheets. Top - antiparallel. Bottom - parallel. n = # residues / turn. Ramachandran. Plot of Polypeptide ...
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Copy the s, or just the illustrations into your own ... Oligosaccharides with negatively charged sialic acid residues. Attract positive ions, e.g. Ca ...
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