Atorvastatin Impurity | Atorvastatin Epoxy Tetrahydrofuran Analog - PowerPoint PPT Presentation

Title: Atorvastatin Impurity | Atorvastatin Epoxy Tetrahydrofuran Analog


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What Is Atorvastatin?
Atorvastatin is used to reduce the levels of bad
cholesterol and triglycerides in the blood.
Along with taking this medicine, a change in
diet and regular exercise is recommended. The
medicine helps in reducing the long-term
cardiovascular risks such as stroke, heart
attacks, chest pain etc. Check Out some products
of Atorvastatin
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Category Atorvastatin Catalogue Number
ATV23-100 Cas No 873950-19-7 Molecular
Formula C26H24FNO5 MW 449.47
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• Other Names Of Atorvastatin Epoxy Tetrahydrofuran
  Analog
• Atorvastatin Epoxy Tetrahydrofuran Analog (USP)
• Atorvastatin Dihydroxy Epoxy Impurity
• Atorvastatin Photo Degradation Product -
  ATV-FXA2
• 4-(4-Fluorophenyl)-2,4-dihydroxy-2-isopropyl-N,5-d
  iphenyl-3,6-dioxabicyclo 3.1.0hexane-1-carboxami
  de

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Category Atorvastatin Catalogue Number
ATV63N-10 Cas No 1315629-79-8 (Sodium salt)
873950-18-6 Molecular Formula
C33H34FN2NaO7 MW 612.62
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• Other Names Of Atorvastatin FX1 Impurity
• Atorvastatin FX1 Impurity
• Atorvastatin Epoxy Pyrrolooxazin 7-Hydroxy Analog
  (USP)
• Atorvastatin Degradation Product - ATV-FX1
• Atorvastatin Cyclic Fluorophenyl Impurity
• Atorvastatin Cyclic 7-Hydroxy Impurity
• 1b-(4-Fluorophenyl)hexahydro-ß,7-dihydroxy-7-(1-me
  thylethyl)-1a-phenyl-7a-(phenylamino)carbonyl-3H
  -oxireno3,4pyrrolo2,1-b1,3oxazine-3-butanoic
  acid sodium salt
• (3R)-4-(1b-(4-Fluorophenyl)-7-hydroxy-7-isopropyl-
  1a-phenyl-7a-(phenyl carbamoyl)
  hexahydro-1aH-oxireno2\\\',3\\\'3,4pyrrolo2,1-
  b1,3oxazin-3-yl)-3-hydroxybutanoic acid sodium
  salt

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Category Atorvastatin Catalogue Number
ATV64N-10 Cas No 1316291-19-6 (sodium salt)
873950-17-5 (acid) Molecular Formula
C33H34FN2NaO7 MW 612.62
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• Other Names Of Atorvastatin FXA Impurity
• Atorvastatin Cyclic Isopropyl Impurity
• Atorvastatin Epoxy Pyrrolooxazin 6-Hydroxy Analog
  (USP)
• Atorvastatin Cyclic 6-Hydroxy Impurity
• 4-6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopr
  opyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H
  -pyrrolo2,1-b1,3oxazin-2-yl-3-hydroxybutanoic
  acid sodium salt

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Category Atorvastatin Catalogue Number
ATV68C-100 Cas No 148127-12-2 Molecular
Formula C33H32FN2O6. 1/2 Ca MW 591.66
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• Other Names Of Atorvastatin Pyrrolidone
  Phenanthrene Calcium
• Atorvastatin Pyrrolidone Phenanthrene Calcium
• Atorvastatin Lactam Phenanthrene Calcium
• (ßR,dR)-9-Fluoro-2,3-dihydro-ß,d-dihydroxy-3-(1-me
  thylethyl)-2-oxo-3-(phenylamino)carbonyl-1H-dibe
  nze,gindole-1-heptanoic acid calcium salt

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