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Title: PowerPoint Author: Zhang Ying Jian Last modified by: Created Date: 9/29/2001 2:13:45 AM Document presentation format
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The Caspases, and Their Role in Apoptosis. Some caspases have long ... http://homepage.ntlworld.com/markhewitson/ntlup.swf. Caspases are:- Cysteine proteases ...
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A Role for Caspases During Viral Infection of the Coccolithophorid, ... There is a misconception that phytoplankton are immortal unless eaten by grazers. ...
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... PLCg STAT NIK IKK Smad STAT STAT STAT Smad Smad Smad PLCb Caspases Phosphorylation is key A. Receptor tyrosine kinase (RTK) ... (Ligand) Notch (receptor) ...
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Animal Genetics and Breeding Division, #Animal Biochemistry ... 'Extrinsic Pathway' 'Intrinsic Pathway' MAJOR PLAYERS IN APOPTOSIS. Caspases. Adaptor proteins ...
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Activating mutations in AKT or inactivating mutations in PTEN ... p53 - Activated by DNA damage. ... Active caspase-8 activates 'downstream' caspases, which ...
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Neural tube (3 wk) / nervous system) Three subdivisions (future forebrain, midbrain, hindbrain) ... Diablo gene released. Block IAPs. Caspases no longer ...
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Biological Basis of Downs Syndrome and Alzheimer's Disease. Trevor Phinney. Alex Hansler ... other downstream caspases that have direct effects on cell death ...
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Pr C . Preudhomme ... 1 MAP/SAP kinases PI3 kinase Akt Cytosquelette ADHESION PROLIFERATION APOPTOSE BAD Cytochrome C Caspases Prot ine kinase ADN d pendante DNA ...
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The Death Domain (DD) is an 80aa C-terminal domain shared among a large family ... mt. mt. Bcl-2. Apaf-1. Caspase9. Blk/Bax. Apoptotic Pathways are Initiated on ...
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caspases in the cell: these leads to a 'caspase cascade', resulting in cleavage. of nuclear lamina, DNA and other cellular proteins. p53. Guardian of the Genome ...
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Title: Pr sentation PowerPoint Author: delphine Last modified by: delphine Created Date: 11/22/2004 9:09:29 AM Document presentation format: Affichage l' cran
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The same number of cells must be removed to maintain homeostasis. This occurs by Apoptosis and/or Autophagy. Life. Death. Too Much vs. Too Little Cell Death ...
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Title: xiap Last modified by: User Document presentation format: (4:3) Other titles: Calibri Arial Wingdings ...
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Title: Slide 1 Author: Darth Vader Last modified by: Darth Vader Created Date: 12/13/2006 12:32:59 AM Document presentation format: On-screen Show Company
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Recognize tetrapeptide sequence on substrates (P4-P3-P2-P1). P4 P3 P2 P1 P1' P2' ... SABLE1. Propensity for. secondary structures. Propensity for. solvent exposure ...
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MORT CELLULAIRE CONCEPTS ET VOIES DE MORT NECROSE APOPTOSE AUTOPHAGY NECROSE La n crose est une mort anormale de la cellule (cf. apoptose) Causes possibles : Perte ...
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Chap. 21 Stem Cells, Cell Asymmetry, and Cell Death Topics Cell Death and Its Regulation Goals Learn the basic mechanism of apoptosis and its regulation.
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Biophys. Acta, 1659, 178-189 Virus peuvent 1 ... PM K7 or vIAP KSHV STS, anti-Fas M F1L Vaccinia STS, anti-Fas, PPIX PBR M M11L Myxoma Oxidants, anti ...
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Effects of smoking in human lens epithelial cells Jae-Woong Koh (MD/PhD)1, Nang-Hee Song(MD)1, Gil-Joong Yoon (MD/PhD)2 Department of Ophthalmology, Chosun University ...
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Mutations in proteins that regulate cell proliferation, survival and death can ... Analysis of DNA content with a flow cytometer ...
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life cycle pause between EB and RB stages -stable association ... needed for embryogenesis, immune system maintenance. Necrosis non-programmed cell death. ...
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Alberts et al. Fig 18-3 Apoptosis during the metamorphosis of a tadpole into a frog. ... Alberts Fig 25-47 Two strategies by which effector cytotoxic T cells ...
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Total Cytotoxicity Assay. Immunochemistry Technologies, LLC. www. ... Fast - finish in one day. Sensitive - measure killed and ... from 1 day old piglets ...
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Cancer Biology: Apoptosis
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Apoptosis: Programmed Cell Death A story about 7th October 2002 3 King
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Title: Apresenta o do PowerPoint Author: Paulo Cabeda Last modified by: Jcabeda Created Date: 9/29/2001 2:36:41 PM Document presentation format
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Figure 17.1 Apoptosis Figure 17.2 Phagocytosis of apoptotic cells Key Experiment 17.1: Photomicrographs of a normal worm (A) and a ced-3 mutant (B) Figure 17.3 ...
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can be initiated intrinsically through DNA damage ... Programed Cell Death helps maintain Health DNA DAMAGE p53 The bcl-2 family BH4 BH3 BH1 BH2 TM N C Receptor ...
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( clonal proliferation)
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Cancer When good cells go bad What is cancer? Caner is defined as the continuous uncontrolled growth of cells. A tumor is a any abnormal proliferation of cells.
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Signal Transduction and Apoptosis The wider Bcl-2 family Functional role of CED-9/CED-4/CED-3 complexes Model of receptor-mediated caspase activation Intrinsic cell ...
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TNF 00 12 17 Death Receptors: Signaling and Modulation Science 1998 281:1305 ...
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Programmed Cell Death Death Signaling Pathways TNF/FASL TNF is a protein toxin which is secreted by activated macrophages and monocytes Laster et al., using time ...
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Cristina Kenney, M.D., Ph.D. Normal & Keratoconus corneal fibroblasts. Drosophila eye. Rebecca Hays Ph.D. FAM-VAD-FMK, Max Pix. Annexin V, Max Pix ...
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Mechanisms of Apoptosis and Cytotoxicity
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LEQ: Why is the eukaryotic cell cycle regulated? Key terms: cyclin, growth factor, kinase Reading 5.3 (cancer) Activator: Briefly explain why the daughter cells ...
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APOPTOSIS Apo: Greek: from, away Ptosis: Greek: fall, falling A specific type of cell death first described in 1972 by Kerr, et al in the British Journal of Cancer
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Title: PowerPoint Author: litao Last modified by: zhangql Created Date: 3/3/2005 2:10:52 PM Document presentation format:
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Cell Death Jaroslava Du kov Inst. Pathol. ,1st Med. Faculty, Charles Univ. Prague http://www1.lf1.cuni.cz/~jdusk/
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PUMA. Stress. Mitochondria. Adapted from Ashkenazi A. Nat Rev Cancer 2002;2:420 430. ... of pro-apoptotic members of the BCL2 family of proteins such as PUMA and BAX ...
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Gen tica Molecular Humana Profa. Dra. Ana Elizabete Silva SUM RIO Hist rico e Conceito Tipos de morte celular: Apoptose x Necrose Caracter sticas gerais da ...
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... Woody Allen Cell and Tissue Renewal in Animals Cell death - Apoptosis Cell Death-Apoptosis 2. Cell death - Apoptosis Cell biologists have come to realize that ...
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Ligation of Fas also leads to a disruption in cyto c function in electron transport. ... (primarily caspase-8) recruited to the cytosolic domain of ligated Fas (21) ...
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Fundamentals of Cell Biology Chapter 13: The Birth and Death of Cells Dr. Saeb Aliwaini *
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A research review on Huntington's disease ... Repressed transcription. Leads to Apoptosis? Current Research. Perutz, 1994. What in the CA150? ...
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Apoptosis Mechanism Necrosis Pyroptosis Apoptosis: friend or foe Chlamydia species PowerPoint Presentation Chlamydia modulates apoptosis Chlamydia both induces ...
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Ashkenazi A and Dixit V. Death receptors: Signaling and modulation. ... en une masse rose amorphe. N crose cas euse. La n crose cas euse ne se voit que dans le ...
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Brian Mikkula (Hokkaido University) Maria Miguel 2.Dr. Sipra Banerjee ... Patrick Boyle. Chris Moulton. Shannon Bradley. Summary ...
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Cell corpse engulfment. Cell-cell signaling between the dying cell and the phagocytic cell ... 7 might involve in cell corpse recognition. What is death ligand? ...
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Granzyme B and perforin, proteins released by an effector cell (cytotoxic T cell) ... II (Topo II) to condense chromatin, leading to DNA fragmentation and ...
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... Reglering av apoptos 1 mitokondrier skadas vid hotande celld d cytokrom c l cker ut cytokrom c binder till Apaf ... aflatoxin UV-str lning ...
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Acetaldehyde. Acetate. CO2 H2O. ROS. ADH. MEOS (Cyp2E1) ALDH. Direct Hepatotoxicity ... Cyp2E1 induction a liver injury (chronicity, zonality, other drugs, ...
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Use of molecule other than water as a proton donor or ... donating both bonding electrons to electrophile. Tetrahedral state. Acyl-E state. Acyl-E state ...
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a) R. N. Bose, D. Li, W. W. Yang, and S. Basu. ( 1999) J. Biomolecular Struct. ... c) T. Kelley, S. Moghaddas, R. Bose, and S. Basu. ( 1993) Cancer Biochem. Biophys. ...
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