The Chimeric antigen receptor CAR-T cell therapy has revolutionized the immunotherapy field with its high success rate against hematological diseases. Investigations in the early 1980s conceived the idea about tumor-infiltrating lymphocytes; however, reproducibility in invitro hampered further developments. It was not until 1993 Immunologist Dr. Zelig Eshhar created the first generation of chimeric T cells at the Weizmann Institute, Israel. The first-generation was successful during experiments, although not clinically effective. Since then, over three decades, a significant chunk of scientific intellect and considerable Research in cancer immunology has optimized this technology further. For the complete in-depth article on ‘CAR-T Cell Therapy’, please visit @ https://www.iebrain.com/car-t-cell-therapy-advancements-and-future-perspectives/
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