Hapten PowerPoint PPT Presentations

Cadherin family E- cadherin----- Epithelia cell N- cadherin ... (glycosylation dependent cell adhesion molecule-1) PSGL-1(P-selectin glycoprotein ...

Some very small molecules called haptens can bind to Ab's or TCR's but they ... molecule that can be made immunogenic by conjugation to a suitable carrier ...

Endogenous: typically peptides derived from any protein; an infected cell ... Endogenous: these antigens are presented by MHC-I; they are seen by T-cells with ...

DIAR discovered to be triggered by pre-formed, circulating dextran-reactive IgG antibodies ... Should DIAR be Classified as an Anaphylactoid or an Anaphylactic Event? ...

Viable epidermis/dermis -- antiinflammation, anesthetics, antihistamine, antipruritic ... Hapten contacts skin epidermis. Hapten complexes with protein ...

To compare and contrast immunogen, antigen & hapten ... Some glycolipids and phospholipids can be immunogenic for T cells and illicit a ...

Cell-Cell Interactions, T-Independent Antigens, CD5 B Cells, Cytokines T Cell-B Cell Interactions (hapten-carrier effect) Th cells recognize carrier, B cells ...

C3b initiates formation of a membrane attack complex (MAC) ... Haptens are found in poison ivy, dander, some detergents, and cosmetics. Antigenic Determinants ...

C3b initiates formation of a membrane attack complex (MAC) ... Haptens are found in poison ivy, dander, some detergents, and cosmetics. Antigenic Determinants ...

4. In Vivo Studies for Induction of Humoral Response ... Hapten-Primed and Carrier-Primed Cells. Are Separate Populations. A Peripheral Lymph Node ...

Introduction. Authors aim to show that natural killer (NK) cells are involved in ... Mice devoid of T and B cells can elicit hypersensitive responses to haptens that ...

Title: Gram Reaction Subject: Gram staining Author: Hugh Fackrell Last modified by: Hugh B. Fackrell Created Date: 10/18/1996 12:08:06 PM Document presentation format

Imagine being able to design a chemical reaction in much the same way that a computer programmer designs a software program. Perhaps you want to create an enzyme that ...

IgG2A Intact Mouse Antibody - Mab231 (PDB ID 1igt, 1992) ... alizarin red (Az, C14H8O7S, Kd=40nM), 2,4-dinitrophenyl (DNP, C6H4N2O5, Kd=20nM) Ab1 ...

Title: Slide 1 Author: H00MAN Last modified by: acadpm01 Created Date: 9/18/2006 6:47:29 PM Document presentation format: On-screen Show (4:3) Company

Antigen Foreignness and specificity of antigen Factors that influence immunogenicity Classification of antigen Nonspecific stimuli for immune response ...

-Jasmine Kaur An antibody is a protein used by the immune system to identify and neutralize foreign objects like bacteria and viruses. Each antibody recognizes a ...

Immunology (elective) MLIM-101 Prepared by: Dr. Mohamed S. Abdel-Latif Learning Outcome: At this time you should know the following: 1. To compare and contrast ...

Immunology Innate - Adaptive Immunity Specificity Memory Tolerance Blood Components Erythrocytes Lymph Leukocytes Macrophage Lymphocytes Cytokines Plasma ...

Bio 328 Immunology Antigens

Title: Kuby Immunology 6/e Author: Kindt, Goldsby, Osborne Last modified by: sb Created Date: 12/24/2002 1:08:46 AM Document presentation format: On-screen Show (4:3)

... Heterogeneous causative gene mutations + THALASSAEMIA MOLECULAR PATHOGENESIS 1. PROMOTOR REGION MUTATION - Reduced transcription of mRNA by 75% ...

not usually immunogenic) 3. Chemical complexity. Homopolymers ... to degradation so they are not immunogenic. Large, insoluble molecules are more susceptible ...

To describe the cell-cell interactions which occur in 1) Ab ... acting in autocrine or paracrine fashion. Central role of Th cells ... have high affinity ...

Title: Immunoglobulin Structure and Function III Effector Mechanisms of Humoral Immunity Lecture 12 August 10, 2004 Lecturer: Wolcott Reading for Lectures 11-13: Kuby ...

Title: Author: lingzhang Last modified by: xiaowuhong Created Date: 11/10/2000 8:17:50 AM Document presentation format:

Substance that can be recognized by immunoglobulin receptors of B cells and T ... Gell and Banacerraf (1959) compared humoral and cell mediated responses to ...

Title: Kuby Immunology 6/e Author: Kindt, Goldsby, Osborne Last modified by: sb Created Date: 12/24/2002 1:08:46 AM Document presentation format: On-screen Show (4:3)

T cell epitope. 3. Pathogens/Invaders. Disease Causing Agents ... Prediction of CTL Epitopes (Cell-mediated immunity) ER. TAP. Innate Immunity. Vaccine Delivery ...

V and C domains share the basic Ig fold. Differences between the two domains ... The antibody repertoire of an individual could be as large as 1016 ...

Chorismate Mutase-catalyzed Conversion of Chorismate to Prephenate Conformation of Chorismate in ... Figure 13.4 Ab initio calculations disfavor pathway e No ...

Continued release of ADH despite fluid intake, interferes with the ... COPD and nicotine are examples of these, however the direct MOA is unknown. ...

Incomplete Freund's adjuvant-oil-in- water emulsion. Complete Freund's adjuvant-oil-in-water emulsion plus dead Mycobacteria. Aluminum hydroxide gel ...

Immunogen- Substance capable of generating a specific immune response and ... 1000-6000D May or May not be ... Continuous/Linear-Single polypeptide segment. ...

IMMUNOLOGY Sherko A Omer ... (e.g., malaria). Diseases are of unknown aetiology and pathophysiology and with a hereditary pattern of distribution.

Title: Chapter 2 Antigen Author: Jiaxin Wang Last modified by: walkinnet Created Date: 3/14/2005 2:58:16 PM Document presentation format:

PRESENTS Dr. S. Craig Wagstaff SANUM THERAPY FOR WOMEN S HEALTH WOMEN S HEALTH Conditions to be discussed: Premenstrual Syndrome Infertility Dysmenorrhea ...

Innate Immunity. Adaptive Immunity(acquired) Cell Mediated Immunity (CMI) Humoral Mediated Immunity (HMI) Type of Immunity ... Epitope (Antigenic determinant) ...

Title: PowerPoint Author: J. S. Yu Last modified by: Created Date: 8/18/2002 1:06:23 PM Document presentation format:

Secondary or peripheral-- lymphnodes, spleen, mucosal lymphoid tissues (GALT, ... Barely organized clusters of lymphoid cells in lamina propria of intestinal villi ...

Cell -Mediated Humoral (Ab) ... Structure Quarternary Structure Factors Influencing Immunogenicity Contribution of the Immunogen Foreigness Size Chemical Composition ...

The result of direct contact with a contact allergen, such as poison ivy and nickel. ... Urushiol from poison ivy, poison oak, and sumac. ...

The next morning, she had puffy eyes and welts resembling large hives on her abdomen. ... 7 days after the onset of the puffy eyes and rash. Questions: ...

Single domain antibodies (sdAbs, or VHH) are the smallest antigen-binding units of antibodies, comprising either one variable domain or one engineered constant domain that solely facilitates target binding. They are popular as a novel class of proprietary therapeutic proteins containing unique structural and functional properties. At Creative Biolabs, we offer one-stop solutions for sdAb development and characterization to promote the identification of novel therapeutic sdAbs to meet your specific project demands. https://www.creative-biolabs.com/sdab/sdab-functional-identification.htm

Title: Slide 1 Author: Awadalla Last modified by: Server Created Date: 9/23/2005 6:45:20 AM Document presentation format: (3:4)

Anatoli Chkaroubo. Jessica Fitzgerald. Alison Hulme. Naomi Steenhof ... Incidence: predicted that out of all ADRs 20% are idiosyncratic ...

Foreignness. Size. Conformational determinants. Sequence determinants. Chemical Composition ... Some glycolipids and phosopholipids can be immunogenic for T ...

... each clone only bears a unique type of Ag receptor The clones of lymphocyte that can recognize self-Ags will be destroyed or learn to tolerance to self Ags ...

Komplement J. Ochotn

Causes of anaphylaxis Immunologic mechanisms IgE-mediated ... 21/100,000 patient-years food allergy 36 ... Venom immunotherapy is highly effective in ...

SRF: Spectral Repeat Finder (SRF) is a program to find repeats through an ... also launched by European Bioinformatics Institute (EBI) Hinxton, Cambridge, UK. ...

These antibodies can be made in large quantities and have a specific affinity ... the Methodist Hospital Houston, TX, USA, prior to commencement of radiotherapy. ...

Applications of Molecular Imprinting Technology to Immunoassays Roger L. Bertholf, Ph.D. Associate Professor of Pathology University of Florida Health Science Center ...

Allergic reactions of delayed type lie in the base of development of infectious-allergic diseases (tuberculosis ... and food allergy, some autoallergic diseases ...

They are often associated with staphylococcal products and are involved in enterotoxemia and toxic shock syndrome in humans. Superantigens (SAgs) ...

Title: PowerPoint Presentation Author: Gamal Ahmed Last modified by: Jihan Abdelmenam Created Date: 1/1/1601 12:00:00 AM Document presentation format