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Imatinib 400 mg is an oral chemotherapy medication. It acts by stopping the Bcr-Abl tyrosine kinase

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Pr C . Preudhomme ... 1 MAP/SAP kinases PI3 kinase Akt Cytosquelette ADHESION PROLIFERATION APOPTOSE BAD Cytochrome C Caspases Prot ine kinase ADN d pendante DNA ...

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Targeted therapy of CML with imatinib mesylate Gleevec

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Treatment of CML Transplant or Imatinib? Mark B Juckett MD Section of Hematology/BMT University of Wisconsin CML - Age specific incidence Clinical Course: Phases of ...

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Structure of Imatinib (STI571, CGP 57148B) Class: Phenylaminopyrimidines, 589.7 mw Cellular Selectivity of STI571: IC50[ M] Kinases Inhibited Kinases Not Inhibited v ...

... La LMC est caract ris e par la pr sence d une anomalie cytog n tique acquise, la translocation t(9;22)(q34;q11) ou chromosome Philadelphie (Phi).

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The presentation by Shah details the 18-month cytogenetic response data with dasatinib as 78 percent versus 70 percent with imatinib in CML.

The Incidence of BCR-ABL Mutations in Patients with Newly Diagnosed CML-CP Treated with Nilotinib or Imatinib in ENESTnd: 24-Month Follow-up

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Mutation with insensitivity to imatinib ... Advanced GIST on Imatinib 400 mg/day (N=400) Measure Imatinib Plasma Level 1,100 ng/mL (N=100) ...

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Figure 2: Progression to aP/bc on Treatment Larson RA, Kim D, Rosti R, et al. Comparison of nilotinib and imatinib in patients (pts) with newly diagnosed chronic ...

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