Isocitrate PowerPoint PPT Presentations

This reaction is virtually identical to the pyruvate dehydrogenase reaction ... It includes three enzymes, homologous to E1, E2, and E3 of the PDH complex, as ...

Structural and Phylogenetic Relationships of Eukaryotic and Some Prokaryotic NAD ... Anthony Arment, Central State University, and John Ferguson, Bard College ...

FAD. Reduction. Oxidation. NADH (electron carrier) REDUCTION of NAD Oxidized form (low energy) ... FAD. NAD NAD Citrate. Isocitrate. Ketoglutarate ...

Citric Acid Cycle * ... Citrate synthase Aconitase Triose Phosphate Isomerase Isocitrate Dehydrogenase * TCA Cycle Overview Pyruvate Acetyl CoA Oxaloacetate Citrate ...

Work involves organizing and building molecules, pumping substances into and out ... and another is added back, converting it to an isomer known as Isocitrate ...

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Cyclic, anabolic biochemical pathway

Citrate Synthase. Aconitase. Krebs Cycle, Citric Acid Cycle ... Krebs Cycle, Citric Acid Cycle. Acetyl CoA 3 NAD FAD GDP Pi 2 H2O ...

Citric Acid Cycle. Gylcolysis. TCA Cycle. Electron Transport and. Oxidative phosphorylation ... (aka Citric Acid Cycle, Krebs Cycle) ...

Reactions of KC occur in mitochondrial matrix. Common final degradative pathway for breakdown of monomers ... Flux increases as contractile activity increases ...

Yp/s Yield of product per substrate consumed. Yp/x Yield of product per cell ... Vmax=389 mM/min. Dehydrogenase (IDH) Km=8 mM. Vmax=625 mM/min. Glyoxylate shunt ...

Title: Biochemistry: A Short Course Author: Tymoczko, Berg, Stryer Last modified by: Pare, Paul Created Date: 12/24/2002 1:08:46 AM Document presentation format

Title: Slide 1 Author: Lee Richard Walker Last modified by: Ralf Created Date: 7/25/2004 12:21:18 PM Document presentation format: On-screen Show Company

The Krebs Cycle (Citric Acid Cycle) By Zuzana Kollarova Krebs Cycle Enzymes in the matrix of the mitochondria catalyze a cycle of reactions called the Krebs cycle.

Citric acid cycle Production of acetyl-CoA Reactions of citric acid cycle Regulation of the citric acid cycle

An incomplete citric acid cycle in. some anaerobic bacteria. aKG ... TCA cycle is 'amphibolic' Four anaplerotic reactions generate oxaloacetate or malate. ...

Step 6: Oxidation of Succinate to Fumarate. 1 mole FADH2 produced ... Step 7: Hydration of Fumarate to Malate. Stereospecific enzyme: D-malate is not a substrate ...

Chapter 12 (part 1) Citric Acid Cycle. Gylcolysis. TCA Cycle. Electron Transport and ... Protein/amino acid. Catabolites feed. Into the TCA Cycle. Fats ...

Plant Carbohydrate Biosynthesis Glyoxylate cycle Biosynthesis of starch and sucrose Synthesis of cell wall polysaccharides Integration of carbohydrate metabolism in ...

TPP = thiamine pyrophosphate. substrates. products. prosthetic group. coenzymes. CO2. FADH2 ... Thiamine. Prosthetic. Thiamine pyrophosphate. E1. Vitamin ...

The Citric Acid Cycle Dr. Sooad Al-Daihan Biochemistry department Introduction Also called citric acid cycle or the Krebs cycle (after its discoverer, Hans Krebs).

Tricarboxylic Acid Cycle (TCA), Krebs Cycle Occurs totally in mitochondria Pyruvate (actually acetate) from glycolysis is degraded to CO2 Some ATP is produced

whereas pyruvate dehydrogenase and TCA cycle reactions take place in ... reactions, they are replenished by anaplerotic reactions in the cells (indicated ...

Chapt. 20 TCA cycle Ch. 20 Tricarboxylic acid cyle Student Learning Outcomes: Describe relevance of TCA cycle Acetyl CoA funnels products Describe reactions of TCA ...

Title: PowerPoint Presentation Author: Reem Last modified by: Norah Created Date: 1/1/1601 12:00:00 AM Document presentation format: On-screen Show (4:3)

From Lehninger Principles of Biochemistry The Citric Acid Cycle has Eight Steps From Lehninger Principles of Biochemistry Step 6: ...

... King Saud University Fates of Pyruvate Oxidative decarboxylation into Acetyl CoA: the enzyme is pyruvate dehydrogenase complex (PDH). It occurs in mitochondria.

Glucose is an excellent fuel with it's oxidation liberating 2,840 kJ/mol of free ... acts or supplies a terminal electron acceptor for fermentative processes ...

-2.05 -5.94 -5.43 36.71 31.27 35.52 0.70 0.46 0.82 0.02 0.26 0.27 17.50 0.91 93.91 6.73 1741.25 212.78 72.88 10.67 1262.50 203.76 23.87 3.75 % ...

If the citrate cycle is an engine, what is the fuel, the energy output, and the ... results in the transfer of 2 e- to the FAD moiety, which in turn, passes the ...

Chapter 19 The Tricarboxylic Acid Cycle Biochemistry by Reginald Garrett and Charles Grisham Essential Question How is pyruvate oxidized under aerobic conditions ...

Glutathione reductase contains FAD. Reaction of glutathione with peroxides ... 3NAD FAD GDP Pi acetyl-CoA. 3NADH FADH GTP CoA 2CO2. Overall reaction ...

Free energy changes in the citric acid cycle. Table 21-2. Reaction Enzyme DG ' DG' ... Citric acid cycle intermediates are always in flux ...

3NAD FAD GDP Pi acetyl-CoA. 3NADH FADH GTP CoA 2CO2 ... The FAD on the enzyme ... reductase contains FAD. Reaction of glutathione ...

Reactions, regulation and importance of citric acid cycle

Regulation of the Citric Acid Cycle. The Glyoxylate Cycle. Introduction ... The oxidation uses the citric acid cycle, the electron transport chain, and ...

3. Transfer of the acetyl group to CoA by E2 ... by i) NADH and acetyl CoA (inhibitors) ... Acetyl-CoA GDP Pi 3 NAD Q 2 CO2 CoA GTP 3 NADH QH2 ...

NOTES: Chapter 9 (Part 2): Glycolysis & Krebs Cycle (9.2 & 9.3)

The Citric Acid Cycle, Krebs Cycle, Three Carboyxlic Acid Cycle

Blood cancer is a disease wherein the cancer develops in the bone marrow. Bone marrow is the place where the blood is produced. The cancer tumours develop when abnormal blood cells start growing out of control. Three main types of blood cancer are leukemia, lymphoma and myeloma.

Glyoxylate Regeneration Cycles Mila Chistaserdova and Mary Lidstrom as a result of their work using mutants and some biochemistry produced many complex pathways, ...

... development to understand the possible side effects of the drug in the metabolic ... concentration('creatine',down,8). concentration('creatinine',down,8) ...

Fish and silkworms contain the enzyme thiaminase, which degrades thiamin. ... the symptoms of beriberi caused by ingesting too much raw fish and silkworm. ...

D) what is the DE0' and DG for the oxidation of lactate to pyruvate by. NAD ... This value is important because lactate must be regenerated after ...

Chapter 12 - The Citric Acid Cycle. The citric acid cycle is involved in ... Intermediates of the citric acid cycle are precursors for carbohydrates, lipids, ...

Fumarase 8. Malate Dehydrogenase Reduced Coenzymes Fuel the Production of ATP Glucose degradation via glycolysis, citric acid cycle, ...

Summary of Anaerobic Glycolysis. Glucose 2 ADP 2 Pi. 2 Lactate 2 ATP 2 H2O 2 H ... Glucose 6 O2 6 CO2 6 H2O. Go' = -200 kJ/mol. Go' = -2866 kJ/mol ...

MYCOBACTERIUM TUBERCULOSIS PROTEOME M. tuberculosis- intracellular pathogen - TB prevalent in Africa and Asia - 1/3 population is infected - 8 million new cases per year

Title: Carbohydrate anabolism Author: Biological Sciences Universit Last modified by: UW - Parkside Created Date: 10/20/2002 4:31:05 PM Document presentation format

Discovered in 1937 by C. Martius. First discovered in mammals ... ferritin H IRE (bullfrog) bound to IRP1. Two-point contact with the IRE: ...

Chapter 19 The Tricarboxylic Acid Cycle Biochemistry by Reginald Garrett and Charles Grisham The electrons transferred from succinate to FAD (to form FADH2) are ...

The Conversion of Pyruvate to Acetyl-CoA Involves Multiple Coupled Redox Reactions ... Citrate Synthase Generates Citrate from Acetyl-CoA and Oxaloacetate ...

Chapter 19. The Citric Acid Cycle. Mary K. Campbell. Shawn O. Farrell ... produced by this means, its principal source is the pentose phosphate pathway ...

Dep. of Chemistry & Biochemistry Prof. Indig Chemistry 501 Handout 16 The Citric Acid Cycle Chapter 16 Lehninger. Principles of Biochemistry. by Nelson and Cox, 5th ...

Chapter 19 Bioenergetics; How the Body Converts Food to Energy

Nutrition, Growth and Metabolism, Lecture 26 Dr. Alvin Fox * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * KEY TERMS Obligate aerobe Obligate anaerobe ...