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I endorse the proposal by Manfred Schliwa (second nomenclature scheme based on ... The numbering by Schliwa preserves the widely used kinesin I and II nomenclature. ...
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Department of Chemistry and Biochemistry. University of Notre Dame ... B. Baker and Biochemistry Group. K. Vaughan and the Cell Biology Group ...
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Silica beads (0.5 mm) with nonspecifically bound kinesin captured in an optical ... yielded kcat = 680 31 nms-1 and Km = 62 5 mM. ...
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takes several hundred 'steps' along a microtubule without detaching ... kinesins were imaged moving along sea-urchin axonemes with a custom-built prism ...
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Organizer: Carolyn Lawrence, MaizeGDB at Iowa State University ... E.g., microtubule depolymerization (MCAK, Klp67a/Kip 3, Kar3/C-terminal) ...
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What are the evolutionary relationships of kinesins? ... Metazoan: mouse/human, fly, worm, fish (Fugu/Danio), frog, tunicate (Ciona) ...
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... observation of encounters between single molecules of kinesin ... synapse, a relatively high tau concentration facilitates kinesin dissociation (red arrow) ...
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Is the first individual of a species to be described in the literature ... such that the original name takes precedence and the person naming the organism ...
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How does kinesin walk? Chuang Wu. Molecular Biophysics III. Thursday 19 ... The results strongly support a hand-over-hand (walking) model for kinesin motility. ...
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... kinesin dynein cAMP cAMP pigment cells ATP ADP ATP ADP ADP ATP ADP ADP-Pi Kinesin MT-motor proteins and the transported elements (Hirokawa, N. Science 1998, ...
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Zwichel is a microtubule base motor protein (kinesin). Kinesins form mostly homo or heterodimers. They are characterized by their N-or C-terminal motor domain.
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Microtubule track. Motor proteins Kinesins, Dyneins. Actin track. Motor protein Myosins. Microtubules maintain polarity Microtubules (red) DNA ( blue)
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Crystal Structure of KIF1A: monomeric, processive kinesin. Neck linker exchanged for the one from conventional kinesin ... more detail we used the nowclassical ...
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Cartoon Dynein with Cargo on Microtubule. Ross Lab - Biophysics ... Dynein, Katanin, Ncd Kinesin, Destabilizing Kinesin-14 Family ...
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Rates: slow/ 1mm/day orthograde (anterograde) only. fast/ 400 mm/day orthograde ... fast, intermediate require microtubules. kinesin - orthograde transport ...
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Fast: 400mm/day (organelles: synaptic vesicles, mitochondria, etc.) Slow:1-2mm/day (structural proteins: actin, microtubules, etc.) Kinesin: a protein motor ...
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Much is still unknown about the mechanisms of kinesin, especially in-vivo ... Chick embryo neurons. Same patterns as PC-12? Changes over more limited lifetime? ...
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Movements observable with light microscope, using phase contrast or interference contrast ... Drosophila gene 'Sunday Driver' has phenotype. similar to kinesin ...
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'T' Form (GTP-Bound Form) Grows at the End 'D' Form (GDP-Bound Form) Shrinks at the -End ... University of Porto Rua Campo Alegre, Portugal. Microtubules and Kinesin ...
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Title: Slide 1 Author: Jonathan Scholey Last modified by: Jonathan Scholey Created Date: 9/30/2006 3:00:19 PM Document presentation format: On-screen Show
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Microtubule motors Text and image sources are included using the notes function of this file Intracellular transport vesicles Fast Axonal Transport Freeze!
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Cytoskeleton & Molecular Motors (6/20) ATPase ...
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CHAPTER 9 The Cytoskeleton and Cell Motility Microtubules (11) Microtubules (12) Basal Bodies and Other MTOCs Basal body structure where outer microtubules in a ...
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Proteins manufactured in cell center move to cell edge ... When depleted in Xenopus extracts, MTs become very long. Red: MTs. Blue: DNA. Scale: 20 microns ...
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Citoscheletro (II) Organizzazione dei microtubuli Organizzazione dei microtubuli Le tubuline a & b (55 kDa, omologhe) legano GTP/GDP. a-Tubulina lega GTP (non ha ...
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Amyloid Precursor Protein APP (relationship to Alzheimer's disease) ... Amyloid Precursor Protein (APP), important in Alzheimer's disease, may be a ...
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Optical System of Light and Electron Microscopes.
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Title: Barroso et al. and a role for TAP Author: Karen Bernd Last modified by: Karen Bernd Created Date: 10/31/2002 1:18:45 AM Document presentation format
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Kathy Franks-Skiba. PETER KOLLMAN, UCSF RON VALE, UCSF. Todd Minehardt Sarah Rice. ROBERTO CAR, PRINCETON. DAVID ADCOCK, LONE STAR BIOTECH ...
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Outline Basic Idea Simple Theory Design Points Calibration of Forces Selected Biological Applications *
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many mammal. cell types. widely distrib. platelets, muscle, fibroblasts. Amoeba ... Melanocytes (mammals) secrete melanosomes which are. taken up by the keratinocytes ...
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Protein Modularity and Evolution: An examination of organism complexity via ... Compile data into a more informative table - Can I trace domain or protein evolution? ...
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Transport of Golgi, lysosomes. Endo/exo/pinocytosis. Polarization. Gastrulation. Cell motility ... Myosin V An Atypical Myosin Motor ...
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Eukaryotic cell Skeletal System. Three well defined filamentous ... Vesicles, Mitochondria, Lysosomes, Chromosomes. Motor proteins Three families. Myosins ...
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generate force for the movement of chromosomes, organelles, and whole cells ... This Sprite is named Twink. Ciliated epithelium of human trachea. Flagellum on sperm ...
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Title: Slide 1 Author: Jamie Pighin Last modified by: Jamie Pighin Created Date: 5/28/2004 6:12:53 AM Document presentation format: On-screen Show Other titles
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Transports lipid droplets to positive end of nuclei ... Procedure: fly embryos. Learned fruit fly embryo preparation techniques (staging, peeling, mounting) ...
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Nanomedicine A New Frontier for Physics Jens-Christian D. Meiners University of Michigan Dept. of Physics and Biophysics Research Division Subcellular Structures ...
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Molecular Machines: Packers and Movers, Assemblers and Shredders Debashish Chowdhury Physics Department, Indian Institute of Technology, Kanpur
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A Minnow, an E. Coli and Ubiquinone. 3 x 10-6. 10-13. 3.4 x ... Minnow. RF Fox FNAL 2006. 11. Biological Energy Couplings. Photon energy (electron excitation) ...
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Cellular Automata Modelling of Traffic in Human and Biological Systems Andreas Schadschneider Institute for Theoretical Physics University of Cologne
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Motor Proteins and Cell Motility
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Bacterial Pathogenesis and the Cytoskeleton. Bacteria utilize functions of the ... B.M., D.Bensimon, V.Croquette, PNAS 2000. dNTP-dependent motors ...
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Applications of non-equilibrium models in biological systems Yariv Kafri Technion, Israel Look at two motors Solving master equation (as long as have a bound ...
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(should they be expected generically??) Models of molecular motors (ratchets) ``rectify Brownian motion Two channels for transition, ...
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Internal framework maintaining position of the organelles ... Form cytoskeleton, mitotic spindle, centrioles, core of cilia and flagella ...
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Distribution of vesicles, intermediate filaments and organelles within the cytoplasm ... of axoplasmic transport causes a traffic jam on the proximal side of the ...
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The catalytic power and specificity of an enzyme is a product of the protein structure. ... Hen egg white lysozyme (HEWL) 14.6 kD, 129 aa's. Function ...
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Myosin V orientates the mitotic spindle in yeast. Yin, Pruyne, Huffaker, Bretscher ... Lee, et al., 2003. Dynein-cortex interactions ...
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Title: Von Ameisen und Menschen Author: Andreas Schadschneider Last modified by: Andreas Schadschneider Created Date: 11/24/2002 3:50:39 PM Document presentation format
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Biophysics Master Course, Fall 2002 Some of the physics cells have to deal with: Random walks, diffusion and Brownian motion Background reading: Frederick Reif ...
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I use these PowerPoint s in cell biology lectures that I give to first year ... Does anybody have a cold can of ATP for this guy. Motor MAPs & traffic ...
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