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Administration Pre-Angiography (Upstream) and PCI Likely (Downstream) *12 g/kg bolus over 30 min (upstream) and 10 g/kg bolus & 25 g/kg bolus (downstream) ...

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diagnosed in ambulance or referral center. ASA 600 mg clopidogrel. Angiogram. Tirofiban ... Angiogram. Tirofiban. provisional. Tirofiban. cont'd. PCI *Bolus: 25 ...

Mutant I domains and a ligand-mimetic, conformation-specific Fab. Binding of AL-57 requires Mg2 ... Arg-Gly-Asp-mimetic antagonist to aIIbb3integrin. tirofiban ...

IIb/IIIa antagonists differ in receptor affinity, ... Clopidogrel (Plavix), Ticlid. Aggrastat (tirofiban) ReoPro (abciximab) Integrilin (eptifibatide) ...

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Treatment with Enoxaparin and Tirofiban in acute MI (TETAMI) M.Cohen et al, Beth Israel Hospital, NJ 1224 STEMI pts, no reperfusion,

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Title: PowerPoint-Pr sentation Author: MD Last modified by: oem Created Date: 4/26/2004 8:35:39 PM Document presentation format: Bildschirmpr sentation

Incidence of surgery after DES Ospedali Niguarda e Legnano PROTOCOLLO PER LA SOSPENSIONE TEMPORANEA DI CLOPIDOGREL PER CHIRURGIA NON-CARDIACA INDIFFERIBILE IN ...

Title: Antiplatelet therapy and Coronary Interventions Author: GIP Last modified by: Georgios Created Date: 4/5/2003 5:22:09 PM Document presentation format

Clinical Trials of GP IIb/IIIa Inhibition Major Trials of GP IIb/IIIa Inhibitors in ACS GP IIb/IIIa Inhibitors in PCI GP IIb/IIIa Inhibition in Patients With Diabetes

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ACC/AHA UA/NSTEMI Guidelines: Role of GP IIb/IIIa Inhibitors

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Intravenous GP IIb/IIIa Inhibitors Abciximab (ReoPro) Has a rapid, high affinity to platelets within minutes Dissociation slowly from GP IIb/IIIa receptor Clears ...

Association of Troponin Elevation with Risk of Mortality in Acute Coronary Syndromes % Mortality at 42 Days % % % % % 831 174 148 134 50 67 Antman EM. N Engl J Med ...

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Platelet Gp IIb/IIIa receptors play a pivotal role in platelet-mediated thrombus ... Thrombocytopenia/cytosis. Platelet inhibitors ...

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Acute Coronary Syndromes ... of the ECG Specificity approx 50% for ischemia The normal or non-diagnostic ECG Special ECGs LM Disease Wellens Syndrome Wellens ...

ANTIPLATELET TREATMENT IN HIGH-RISK PATIENTS Stefano Savonitto Dipartimento Cardiologico A. De Gasperis Ospedale Niguarda Ca Granda Milano, Italy

Coronary intervention PCI or CABG Acute Coronary Syndromes Stable Angina Unstable Angina STEMI NSTEMI Character of pain Exertional pain Rest pain Rest pain Rest ...

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