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Cell fates are specified by particular combinations of homeotic gene ... PcG mediated gene silencing can be ... Ezh1; Ezh2 (human); clf (Arabidopsis) extra sex ...
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Tails of Intrigue: Phosphorylation of RNA Polymerase II Mediates Histone ... SET[Su(var)3-9, Enhancer of zeste (E(z)), and Trithorax]domain-containing. protein ...
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... Epigenetic Modifications Within an Arabidopsis Chromosome Heterochromatin correlates with epigenetic marks DNA ... Mechanisms for Repression Mediated ...
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Epigenetics: Modification of DNA and chromatin to control DNA structure and Gene Expression Histone modifying enzymes often are part of large multi-subunit complexes.
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Histones have repressive post ... Endogenous Fab-7. Endogenous Fab-7 ... Endogenous Fab-7 at the BX-C (Chr.III) 3mm. Fab-X. Fab-X; Fab-71. WT. WT. Fab ...
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Model of Drosophila Anterior-Posterior Pattern Formation Maternal effect genes Zygotic genes Syncytial blastoderm Cellular blastoderm Homeotic transformation of the ...
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Homeotic transformation of the wing and haltere ... Perivitelline space. Fig. 31-16. The dorsal-ventral pathway. Maternal genes ...
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... the major group of genes containing homeoboxes in Drosophila; engrailed ... the insulator scs is localized at interbands in Drosophila polytene chromosomes. ...
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Can be used for both reproductive and therapeutic cloning. ... Bernstein, B.E. Angelina Jolie, Brad Pitt, Jennifer Aniston et al. (2006) Cell 125: 315-326 ...
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Igk gene enhancer (Y. Bergman--Jerusalem) ... Imposes a cis-obligation on enhancers ... Very few proteins (outside of enhancer binding proteins) have been identified ...
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... obesity , schizophrenia, Beckwith-Wiedemann syndrome, Alzheimer's disease ... Analyses of up- and down-regulated gene clusters ...
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Transcription regulation of complex loci
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Histone H1 further condenses the DNA by binding the linker segments between the nucleosome core ... in the compaction and accessibility of eukaryotic and ...
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methylated K9, K20, K27, K36 are recognized by repressor complexes. repressor complexes recruit HDACs, chromatin remodeling machines ...
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... extend the replicative lifespan of yeast and delay aging in C.elegans and D ... leads to the accumulation of ... into reactive oxygen species ...
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noggin (TGFb superfamily) is sufficient to induce dorsal structures ... functions like noggin to block BMP factor interaction with receptors ...
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The relationship between self-renewal and clonal fate ... Jagged/Notch. Wnt/Frizzled:LRP. TGF. b / BMP-4. leptin. NGF. Shh/Patched. Angiopoietin/Tie-2 ...
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Nematode worm consist of only about 1000 somatic cells and 1000-2000 germ cells. ... The organogenesis gaining the final shape of the differentiated organs ...
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Development of an animal model of t(4;14) multiple myeloma ... Karyotypes of MM are complex - Chr 13 loss common and poor prognostic factor ...
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Slugs contain two major cell types, prespore and prestalk. The slug contains multiple cell types ... labeled Pst cells in slug and culmination. regulation of ...
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Drosophila Body Plan (part 2): Segmentation Drosophila Body Plan (part 2): Segmentation 5 3 anterior posterior Antennapedia complex has five homeobox genes Work ...
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Higher order DNA structure in eukaryotes does not allow for genomic access and ... Properties of PcG and TrxG proteins ... Post translational modification of histones ...
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