Applied Pathology

1
Applied Pathology

• Module 10 Pathology of the reproductive system

2
Readings

• http//www.merckvetmanual.com/mvm/index.jsp?cfile
  htm/bc/110100.htm
• http//patho.vetmed.ufl.edu/teach/vem5162/reproduc
  tive/index.htm

3
Infectious abortion

• Virus
• Developmental abnormalities
• Large numbers of abortions in a small amount of
  time herpesviruses
• Fetal death and resorption
• Bacteria
• Sporadic and low in number
• Protozoa

4
Tissues for abortion diagnosis

• Brain
• Heart
• Lung
• Thymus
• Diaphragm
• Liver
• Kidney
• Spleen
• Stomach contents
• Thoracic or pericardial fluid
• Placenta
• Feed/water sample

5
This sheep fetus has skeletal deformities in the
limbs, sternum and vertebral column. The
condition is caused by a viral infection
affecting the fetus when in the uterus.
6
This is another view of the same fetus. Notice
how the rear limbs are bent forward a condition
known as arthrogryposis.
7
Normal placenta notice how the tissue is
transparent.
Placenta with inflammation. Note how the organ
is thickened and brown.
8
This bovine placenta shows severe inflammation
caused by a bacterial infection with Brucella
abortus.
9
Non-infectious abortion

• Fungal sporadic
• Environmental exposure
• Umbilical cord abnormalities
• torsion
• Endocrine disorders
• Thyroid gland

10
This photo shows the rear limb of an
aborted calf. The plaque-like structures on the
skin are what is seen when abortions occur due to
a fungal infection.
11
This is an equine fetus that aborted due to
twisting of the umbilical cord.
12
This sheep fetus has a goiter, or, enlargement
of the thyroid gland. There are different causes
for this kind of lesion, but it can cause
abortion.
Ovine
13
Hormonal abnormalities

• Estrogen
• Progesterone
• Pyometras
• Open
• closed

14
This is a case of pyometra in a dog. The uterus
is enlarged and filled with purulent material.
This condition can be caused by abnormalities in
reproductive hormones.
15
Pyometra

• http//en.wikipedia.org/wiki/Pyometra

16
End of module 10

• This is the end of module 10. Please proceed to
  module 11, veterinary cytopathology.