Musculoskeletal Physiology and Disorders

1
Musculoskeletal Physiologyand Disorders
2
Bone Injury and Fracture

• Types
• Open vs Closed
• Complications
• Infection (open)
• Fat emboli (lung)
• Deep vein thrombophlebitis (lung)
• Compartment Syndrome

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Compartment Syndrome
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Disorders of Bone
Osteomalacia
Osteoporosis
Paget Disease
soft bones brittle bones fibrotic bones
Low calcium Low calcium ? Etiology Low Vit D Low
Vit D Low estrogen Rickets Low bone
stress hyperthyroidism
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Arthritis
Osteoarthritis
Rheumatoid
Gouty Arthritis
Localized Systemic Systemic wear
tear autoimmune elevated uric acid Not
inflammatory Inflammatory Inflammatory DIP
joints PIP joints Tophi (great toe) ASA-NSAID ASA-
NSAID NO ASA steroids allopurinol methotrexate
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Structure of long bone
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Types of fractures
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The End...