Thermostat

1
(-)
Thermostat
electricity
Heat
()
Igniter
Furnace
spark
()
Negative Feedback System
2
Hypothalamic-Pituitary-Testicular Axis
(-)
Hypothalamus
GnRH
Testosterone and Inhibin
()
Pituitary
Testis
FSH and LH
()
3
Why does the testis produce testosterone?
How could we find out?
Experiments
Castration
Pituitary cells LH
Secondary Sex Chracteristics
Neutralize LH with LH antibodies
Pituitary cells
Secondary Sex Chracteristics Testis Size
Tx with testosterone
LH Testis Size
4
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5
How is the seminiferous tubule organized?
6
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7
What is the function of the spermatogonia?

• Clonal expansion

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10
tubule to rete testis
vas deferens to ampula
rete testis to epididymus
ampula to prostate
epididymus to vas deferens
prostate to urethra