The Membrane Protein Data Bank

1
The Membrane Protein Data Bank

• V. Cherezov, P. Raman, M. Caffrey
• The Ohio State University
• University of Limerick

2
MPDB overview

• Genuine membrane proteins and peptides
• XRD, NMR, ED, CM (no theoretical models)
• PDB, literature and other databases
• Searchable relational database
• Statistics
• Updated weekly
• http//www.lipidat.chemistry.ohio-state.edu/MPDB/i
  ndex.asp

3
Future

• More protein characteristics
• Full crystallization conditions
• Folds classification (SCOP, CATH)
• Expand statistics
• Links to other databases

4
Acknowledgements

• Orla Slattery University of Limerick
• J. Clogston, J. Lyons, Ohio State University
• N. Hoefer, W. Liu and
• Y. Misquitta
• Supported in part by SFI (02-IN1-B266), NIH
  (GM61070,
• GM075915), and NSF (DIR9016683, DBI9981990).

5
Poster presentationSunday, 400-500 pm