Biology 60 Human Physiology

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Biology 60(Human Physiology)

• Introduction

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• Physiology
• from Greek Phusiologia phusis nature logos
  account
• study of processes essential to life function
• relation to anatomy
• Life
• hierarchical in organization
• life functions
• survival needs

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B. Fluid compartments
40 ICF (2/3 of TBW) Total
body water (TBW) 60 of body weight
16 Interstitial Fluid (4/5 of
ECF) 20 ECF (1/3 of TBW)
4 Plasma (1/5 of ECF)
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C.
B.
A.
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Interstitial Fluid - important! - cellular
environment - provides survival needs
ICF
Plasma - important! - dynamic -"serviced" by
body systems (page 5) - exchange with
interstitial fluid only in capillaries - similar
in composition except high concentration of
proteins
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C. Homeostasis
1. Definition concept Claude Bernard c.
1880 term Walter Cannon 1932 constancy
of conditions of the ECF despite external
changes 2. Maintained by control mechanisms
3 components - receptor, control center,
effector examples negative
feedback positive feedback
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• 3. Note
• not constant but vary within limits
• not equilibrium
• mechanistic view of life
• pathology homeostatic imbalance
• avoid teleology

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D. Role of body systems - page 5
CO2 heat O2
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Injury Radiation Microbes Heat (2 ways)
H2O H Urea Na
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H2O nutrients
bilirubin
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E. Plan coverage more tests keep big
picture in mind
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On half sheet of paper please
Name Major Commute distance (one
way) Working? Family?
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• Describe what Claude Bernard meant by the"
  internal milieu What is it? Where is
  it? Why is it important?
• What is wrong with this statement?
• During exercise the heart rate and ventilation
  rate increases because the body needs more
  oxygen.
• Could you describe a smokers addiction to
  nicotine as a negative feedback system?
  Explain.

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• Which bests describes your attitude toward
  physiology?
• I dont see why a nurse needs to know all this
  stuff. How will knowing the difference between
  saturated and unsaturated fatty acids help me on
  the floor?
• All I care about is the grade. Just get me
  through this so I can get on with my life.
• I think I appreciate the relevancy but I am still
  worried about the grade.
• Im a eager beaver learning machine. I am most
  interested in gaining knowledge. The grade will
  take care of itself.