Chapter 2: The Generalized Cell

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Chapter 2 The Generalized Cell

• A quick review

(2.1)
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The Plasma Membrane

• The Fluid Mosaic Model
• Phospholipid bilayer
• Polar heads
• Nonpolar (fatty acid) tails
• Glycolipids
• Cholesterol
• Integral proteins
• Glycoprotein receptors
• Peripheral proteins

(2.2a)
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The Fluid Mosaic Model

• Fluid ?
• Mosaic ?

(2.2a)
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TEM of PM

• Trilaminar structure thought to correspond to
  staining of phospholipid bilayer

(See 2.2b)
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PM Functions

• Barrier nonpolar tails - hydrophobic
• Receptors glycoproteins
• Selectively permeable
• Diffusion of O2, CO2, fat soluble molecules

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PM Functions

• Active transport
• Ion channels pumps
• Exocytosis
• Secretion
• Phagocytosis
• Pinocytosis

(2.2a)
(2.4a)
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TEM of exocytosis or endocytosis (?)

• What is one limitation of TEM?

(2.4b)
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PM Functions

• Endocytosis
• Phagocytosis
• Pinocytosis
• Receptor mediated endocytosis

(2.3b)
(2.3a)
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Cytosol, Organelles, Cytoskeleton

• Be able to recognize and briefly describe
• Mitochondria
• Ribosomes
• rER
• sER
• Golgi apparatus
• Lysosomes
• Peroxisomes
• Microtubules

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Cytosol, Organelles, Cytoskeleton

• Recognize and describe (contd)
• Microfilaments
• Intermediate filaments
• Centrosomes centrioles
• Cytoplasmic inclusions
• Nucleus nucleoli

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Skip Over

• Cell Life Cycle (pp. 40-41)
• Cell Diversity (pp. 41-44)
• Developmental Aspects (p. 45)
• READ Cancer (pp. 46-47)