Update on new WHO

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Update on new WHO UNICEF publications

• Presentation to the Global Immunization Meeting
• New York, 17 19 Feb 2009
• Dr Rudi Eggers
• EPI, WHO Geneva

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Acknowledgments

• WHO
• Mario Condé
• Jhimil Bahl
• UNICEF
• GIM Preparation team
• . Thanks!!

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New WHO/IVB documents in 2008

• An introduction to the Global Immunization Vision
  and Strategy - WHO/IVB/08.13 -
• WHO vaccine-preventable diseases monitoring
  system - 2007 global summary-WHO/IVB/2007
• Immunological Basis for Immunization Module 9
  Haemophilus influenza type b vaccines- ISBN 978
  92 4 159613 8
• Immunological Basis for Immunization Series
  Module 10 Varicella-zoster virus-ISBN 978 92 4
  159677 0

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Immunological basis for immunization

• The main purpose of these module documents is to
  give vaccination professionals a brief and
  easy-to-understand overview of the scientific
  basis of vaccination.
• Updated and new modules
• Tetanus
• Haemophilus influenza type b vaccines
• Varicella-zoster virus
• Modules currently being revised
• Rubella (due March 2009)
• Measles (due May 2009)
• Other modules (General Diphtheria Pertussis
  Tuberculosis Poliomyelitis Yellow fever) to be
  revised in future

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New WHO/IVB documents in 2008

• Influenza
• Meeting with International Partners on Influenza
  Vaccine technology Transfer to Developing Country
  Vaccine Manufacturers-WHO/IVB/08.09
• The Global Action Plan (GAP) to Increase Supply
  of Pandemic Influenza Vaccines WHO/IVB/08.10
• Dengue
• Guidelines for the clinical evaluation of dengue
  vaccines in endemic areas- WHO/IVB/08.12
• Meeting reports
• Proceedings of the Seventh Global Vaccine
  Research Forum, 3-6 December 2006, Bangkok,
  Thailand-WHO/IVB/07.10
• Progress reports
• IVR report 2006-2007- WHO/IVB/08.11
• WHO immunization work 2006-07 highlights-ISBN
  978 92 4 159674 9

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New polio documents in 2008

• Framework for the new GPEI Strategic Plan
  2009-2013
• Polio outbreak response guideline, incl.
• Training material, basic forms (tally sheets)
• Q A and fact sheets
• PowerPoint presentation
• WER - Health conditions for travelers
• to Saudi Arabia for the pilgrimage
• to Mecca (Hajj)

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New position papers 23-valent pneumococcal
polysaccharide vaccine

• Broad review of available data
• Results show protective effect against IPD and
  all-cause-pneumonia among healthy young adults
• Lesser degree of protection against IPD in
  individuals aged gt65 years.
• HOWEVER overall data on the efficacy and
  effectiveness of PPV23 for other age groups are
  inconsistent
• Failed to demonstrate efficacy against IPD or
  all-cause pneumonia in individuals with
  immunocompromising conditions
• In resource-limited settings, the evidence does
  not support routine immunization of the elderly
  and high-risk populations with PPV23 higher
  priority to infant PCV7
• In low-income countries, WHO recommends the
  additional use of other measures that help
  prevent pneumococcal disease
• Need for more efficacious conjugated vaccines or
  other types of vaccines covering the majority of
  the pneumococcal serotypes

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New position paper Typhoid vaccine(live, oral
Ty21a and injectable Vi polysaccharide)

• Annual global incidence of typhoid fever at 21
  million cases, 14 fatal 90 of these deaths
  occur in Asia.
• Two new-generation typhoid vaccines Countries
  should consider the programmatic use of typhoid
  vaccines for controlling endemic disease
• Most countries vaccination only of high-risk
  groups and populations
• Decisions whether to initiate programmatic use of
  typhoid vaccines should be based on local
  knowledge
• Subpopulations at particular risk
• Age-specific incidence rates
• Sensitivity of the prevailing S. Typhi strains to
  relevant antimicrobial drugs
• Cost effectiveness

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New position paper Typhoid vaccine

• Choice of vaccine, choice of delivery strategy
  and choice of target age group depends on local
  immunization programme capacity and other
  logistic and cultural factors
• Vaccination recommended for
• Outbreak control
• Travellers to destinations where the risk of
  typhoid fever is high
• Improved vaccines against typhoid fever are
  desirable
• All typhoid fever vaccination programmes should
  be implemented in the context of other efforts to
  control the disease

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WHO recommendations for routine immunization
schedule - summary tables

• To assist programme managers develop optimal
  immunization schedules, WHO has compiled key
  information on its current routine immunization
  recommendations in to two summary tables.
• Presentation to GIM

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Global MLM modules

• Module 1 Cold chain, vaccines and
  safe-injection equipment management
• Module 2 Partnering with communities
• Module 3 Immunization safety
• Module 4 Supportive supervision
• Module 5 Monitoring the immunization system
• Module 6 Making a comprehensive annual national
  immunization plan and budget
• Module 7 The EPI coverage survey
• Module 8 Making disease surveillance work

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Regional publications of general interest

• AFRO
• Implementing the Reaching Every District
• Approach
• EURO
• Preparing for the Introduction of HPV Vaccine in
  the WHO European Region -Strategy paper
• PAHO
• Operating Procedures of the PAHO Revolving Fund

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UNICEF publications

• The State of the Worlds Children 2008 provides a
  wide-ranging assessment of the current state of
  child survival and primary health care for
  mothers, newborns and children.
• Outlines the most important emerging precepts and
  strategies for reducing deaths among children
  under age five and for providing a continuum of
  care for mothers, newborns and children.
• The State of the World's Children 2009 examines
  critical issues in maternal and newborn health,
  underscoring the need to establish a
  comprehensive continuum of care for mothers,
  newborns and children.
• Outlines the latest paradigms in health
  programming and policies for mothers and
  newborns, and explores policies, programmes and
  partnerships aimed at improving maternal and
  neonatal health.

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Regular newsletters, bulletins

• Global Immunization Newsletter GIN
• Compiled from many different information sources
  and reports by WHO HQ
• Sent out electronically to partners, regions and
  countries
• Polio
• Polio News
• The Polio Pipeline - quarterly update of ongoing
• research in the Global Polio Eradication
  Initiative
• Regional
• Measles and Polio updates
• Lab updates
• AFRO Sub-regional monthly summaries

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Better dissemination Which of the options would
help increase the dissemination of IVB documents
to a greater audience and assure wider use?

• Please assist by filling in the questionnaire in
  your folders

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Thank you