Is there any evidence support effectiveness of coffee enema

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Is there any evidence support effectiveness of
coffee enema?

• Truth and Myth
• Pisaln Mairiang MD.

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Searching strategy

• Pubmed (no limit)
• Keywords Coffee enema,
• Colonic hydrotherapy
• Colonic irrigation

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Searching coffee enema
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Historical aspects of enema therapy

• An ancient theory of autointoxication by
  intestinal waste products.
• Had been practicing among ancient Chinese, Hindu,
  Egyptian medicine

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NJ Taffinder et al Colorectal disease
20046258-60
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Indications asthma,allergies, arthritis, back
pain, headache, insomnia, hyperlipidemia, bad
breath, hypertension, mental disorders,
alcoholism, ulcerative colitis, cancers and liver
insufficiency.
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Gersons hypothesis
Alteration of Immune system
intoxication
asthma allergies arthritis
headache, insomnia, bad breath, mental
disorders, cancers and liver insufficiency.
Bile flow
Bacterial and food waste product
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Bile salt enterohepatic recirculation
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Gersons hypothesis
Repair of Immune system
detoxication
asthma allergies arthritis
headache, insomnia, bad breath, mental
disorders, cancers and liver insufficiency.
Bile flow
Bacterial and food waste product
coffee
coffee
coffee
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Scientific background of coffee enema

• Anaerobic ? decreased energy production and
  promote cancer
• Coffee stimulate bile formation and flow
• Colestol compounds present in coffee act as
• detoxicants by stimulate liver GST
  
• Cancer cells can be killed by inflammatory
• reaction

NO
NO
NO
Yes/No
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Coffee enema and cancer
Leed A, et al. Lancet 199015677-2
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• Safety and complications

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Complications of coffee enema

• Sporadic cases of deaths related to coffee enemas
  
• Pulmonary enema and septicemia in 46-year-old
  woman diagnosed as colitis
• 37-year-old woman with carcinoma of the breast
  developed hyponathemia, hyperkalemia and
  abdominal pain with dyspnea
• John W. Eisele, Donald T. Reay. JAMA
  1980244(14)1608-9.
• Perineal gangrene and rectal perforation
• 
  
  Tan MP et al Ann Acad Singapore
  199928583-5
• Potassium depletion by enemas
• Dumning MF, Plum F. Am J Med 1956789-92.
• Water intoxication
• Ziskind A, Gelis SS. J Dis Child
  1958699-04.
• Polymicrobial enteric septicemia from coffee
  enemas
• Margolin KA, Green MR. West J Med
  1984140(3)460
• Report cases of colonic injury (Burn) from Thai
  endoscopists

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Summary on colonic hydrotherapy

• Colonic hydrotherapy is effective in treatment
  constipation and hepatic encephalopathy
• There is no scientific evidence of its
  effectiveness
• To answer for effectiveness of coffee enema need
  controlled trail study. possible or impossible