Core Concepts in Pharmacology

1
Core Concepts in Pharmacology

• Chapter 1
• Introduction to Pharmacology
• Drug Regulation and Approval

2
History of Pharmacology

• Herbal medicine
• Modern pharmacology
• 1847
• 1890
• What is the central purpose of pharmacology?
• How does the central purpose of pharmacology
  compare with the central purpose of nursing?

3
Terms to Understand

• Pharmacology
• Therapeutics
• Pharmacotherapy (pharmacotheraputics)
• What other disciplines are important?
• How is knowledge of other subject areas
  (disciplines) helpful in understanding
  pharmacology?
• How are these terms connected?

4
Pharmacology and Therapeutics

• What is the role of the nurse in
  pharmacotherapeutics?
• What must the nurse possess in order to perform
  nursing duties related to pharmacotherapeutics?

5
Lets Think About It

• What are some of the challenges of pharmacology
  today?
• What is required of the nurse?

6
Categories of Therapeutic Agents

• Drugs
• Biologics
• Alternative Therapies
• Define the above terms.
• Can you think of examples for each term?

7
Dispensing Drugs

• Prescription drugs
• Over-the-counter (OTC) drugs
• Compare and Contrast the above methods of
  dispensing drugs.

8
Regulating Drugs

• Formulary
• Pharmacopoeia
• Why was it necessary to formally regulate drugs?
• What is the role of the FDA?
• When can a prescription drug become an OTC drug?

9
Stages of Therapeutic and Biologic Drug Approval

• Preclinical investigation
• Clinical investigation
• Review of the New Drug Application (NDA)
• Postmarketing surveillance

10
Recent Changes to Drug Approval Process

• Prescription Drug User Fee Act
• FDA Modernization Act
• What are the benefits to streamlining this
  process?
• What are the drawbacks?