Sarcoidosis

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Sarcoidosis

• Pathology discussion

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Pathology of Sarcoidosis

• The histologic hallmark is lymphangitic
  distribution of non-caseating granulomas with
  Langhans' or foreign body type giant cells
• Within the granulomas there may be calcified,
  rounded, laminated concretions known as
  Schumann's bodies
• With the giant cells there are often star-shaped
  inclusions (Asteroid bodies)
• The above 2 are characteristic, but not
  diagnostic, of sarcoidosis
• There is varying degree of fibrosis around
  granulomas and in the interstitium
• Sarcoidosis is a diagnosis of exclusion.

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Sarcoidosis Lung Gross
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Sarcoidosis Lymphnode
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Sarcoidosis Lymphnode
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Sarcoid granuloma
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Sarcoid granuloma
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Sarcoid granuloma
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Sarcoid granuloma
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Sarcoid granuloma
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Sarcoid granuloma