4th Drug List

1
4th Drug List
2
1
acetazolamide
3
1
carbonic anhydrase inhibitor seldom used as a
diuretic but used systemically to treat acute
narrow angle glaucoma and to prevent/treat acute
mountain sickness
4
2
amiloride
5
2
K sparing diuretic directly blocks channel of
ENaC
6
3
amyl nitrite
7
3
antidote for CN- toxicity oxidizes Hb (Fe2) -gt
metHb (Fe3), pulling CN- off of cytochrome
oxidase in cells
8
4
apraclonidine
9
4
alpha 2 agonist used topically in chronic wide
angle glaucoma
10
5
betaxolol
11
5
Beta 1 antagonist used topically in wide angle
glaucoma
12
6
bumetanide
13
6
Loop diuretic (inhibits NKCC transporter)
14
7
calcium gluconate
15
7
relieves pain from Pb colic (lead poisoning
abdominal pain) administered IV
16
8
captopril
17
8
ACE inhibitor spares K
18
9
chlorthalidone
19
9
thiazide diuretic inhibits NaCl cotransporter in
distal convoluted tubule causes increased
excretion of Na, Cl, K increased reabsorbtion of
Ca
20
10
cyclopentolate
21
10
M antagonist used topically in opthalmology for
opthalmological exam
22
11
deferoxamine
23
11
chelator used in the treatment of Fe poisoning
administered IV or IM
24
12
demeclocycline
25
12
antibiotic that has aquatic (ADH antagonist)
effects
26
13
diazinon
27
13
phosphorylating AntiChE insecticide
28
14
dimercaprol (BAL)
29
14
chelator used in the treatment of Hg and As
poisoning also used in combination with EDTA to
treat Pb poisoning administered IM in peanut oil
30
15
dipivefrin
31
15
esterified EPI used topically in chronic wide
angle glaucoma
32
16
dithiocarb
33
16
chelator used in the treatment of nickel carbonyl
poisoning
34
17
dorzolamide
35
17
CAI used topically in chronic wide angle glaucoma
36
18
echothiophate
37
18
phosphorylating antiChE used topically (as a
last resort) in chronic open angle glaucoma
38
19
EDTA
39
19
chelator used in the treatment of Pb poisoning,
often in combination with dimercaprol
administered IV
40
20
ethacrynic acid
41
20
loop diuretic
42
21
furosemide
43
21
loop diuretic
44
22
homatropine
45
22
M antagonist used topicaly in opthalmology for
opthalmological exam
46
23
hydrochlorothiazide (HCTZ)
47
23
thiazide diuretic
48
24
indapamide
49
24
thiazide diuretic
50
25
isofluorophate (DFP)
51
25
phosphorylating antiChE used topically as a last
resort in chronic wide angle glaucoma (poor
patient compliance due to oily medium)
52
26
latanoprost
53
26
PGF2a analog (prodrug) used topically in chronic
wide angle glaucoma
54
27
lithium
55
27
mood-stabilizing agent that has aquaretic (ADH
antagonist) effects
56
28
losartan
57
28
ARB spares K (causes increase in plasma K)
58
29
malathion
59
29
phosphorylating antiChE insecticide
60
30
mannitol
61
30
osmotic diuretic used to decrease secretion of
aqueous humor in acute narrow angle glaucoma
62
31
metolazone
63
31
thiazide diuretic
64
32
penicillamine
65
32
chelator used in the treatment of Hg, Pb, Cu, and
As poisoning administered PO
66
33
physostigmine
67
33
carbamoylating antiChE used topically in acute
narrow angle and chronic open angle glaucoma
68
34
pilocarpine
69
34
M antagonist used topically in acute narrow
angle and chronic open angle glaucoma
70
35
polythiol resin
71
35
binds organomercurials, interrupting their
enterohepatic cycling administered PO
72
36
pralidoxime
73
36
antidote for phosphorylating antiChE regenerates
active enzyme if administered properly
74
37
propantheline
75
37
M antagonist NOT effective for treatment of
peptic ulcer disease
76
38
pyridostigmine
77
38
carbamoylating antiChE can be used to treat
myasthenia gravis
78
39
sodium nitrite
79
39
antidote for Cn- toxicity oxidizes Hb (Fe2) -gt
metHb (Fe3), pulling CN- off of cytochrome
oxidase in cells
80
40
spironolactone
81
40
K sparing diuretic competitive antagonist of
aldosterone at cytoplasmic MR
82
41
succimer (DMSA)
83
41
chelator used in the treatment of Pb, Hg, As
poisoning administered PO
84
42
tetrahydrocannabinol
85
42
used in chronic wide angle glaucoma if all other
therapies fail or result in intolerable side
effects
86
43
tetrahydrozoline
87
43
alpha agonist used topically as a
vasoconstrictor in the eye
88
44
thiosulfate
89
44
antidote for CN- toxicity facilitates conversion
of CN- -gt SCN- by rhodanese
90
45
timolol
91
45
Beta antagonist used topically in chronic wide
angle glaucoma
92
46
torsemide
93
46
loop diuretic
94
47
triamterene
95
47
K sparing diuretic directly blocks ENaC channels
96
48
spironolactone
97
48
K sparing diuretic competitive antagonist of
aldosterone at cytoplasmic Mineralocorticoid
receptor