Sensitization and Classical Conditioning in Invertebrate Models

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10/18/2005 Sensitization and Classical
Conditioning in Invertebrate Models   Aplysia
Californica   Habituation Circuitry Molecular
Mechanism   Sensitization Circuitry Molecul
ar Mechanism   Classical Conditioning Circuitry
Molecular Mechanism  
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Donald Hebb When an axon of cell A excites cell
B and repeatedly or persistently takes part in
firing it, some growth processes or metabolic
change takes place in one or both cells so that
As efficiency as one of the cells firing B is
increased. Paraphrase Synaptic connections are
strengthened when the presynaptic and the
postsynaptic neurons are active simultaneously.
Paraphrase II Neurons that fire together, wire
together
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Fig. 36-1
Kandel Fig 36-1
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Circuitry Diagram
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Fig. 36-1
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Short-term vs Long Term
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Kandel Fig. 36-2
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Fig. 36-6
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Difference Between Habituation and Adaptation
Mechanism of Habituation? Distributed synaptic
plasticity.
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Sensitization
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Fig. 36-4
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Kandel Fig. 36-3A
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Signal Transduction Pathway
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Kandel 36-3B
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Kandel Fig 36-6
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Kandel Fig. 36-5
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In-class Exercises
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Classical Conditioning
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Kandel Fig. 36-7B
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Kandel Fig. 36-7A
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Kandel Fig. 36-8
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Kandel Fig. 36-5
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In-class Exercises