Scheme 6 Antibody Detection

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Scheme 6Antibody Detection
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Scheme Summary

• 2 send outs of 10 samples
• Report results within 8 weeks
• 2008 43 participants
• 75 concordance between labs
• Two assessment cycles
• Penalty scoring system

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Methodology 2008
ELISA Quikscreen/ B-Screen 7 LATM
5 Biotest 1
Luminex LabScreen 26 Lifecodes 3 Both
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Methodology 2008
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Methodology 2008
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Hidden Negatives

• 8 AB sera
• Total number of results 340
• Number of false positives 55 (16.1)
• 5 CDC
• 50 LS
• 10 labs reported false positives

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Sera Distributed in 2008
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Penalty Point Scoring System for 2008
Penalty Score Each report in agreement
with the consensus 0 Each report not in
agreement with the consensus 4 Each report of an
equivocal result 1 Poor Performer gt8
penalty points in any one cycle Persistent Poor
Performer PP in any two consecutive cycles
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Penalty Points for 2008

• 1st Cycle
• 0 penalty points 29 labs
• 4 penalty points 3 labs
• 5 penalty points 1 lab
• 8 penalty points 3 labs
• 12 penalty points 1 lab
• 16 penalty points 5 labs

• 2nd Cycle
• 0 penalty points 33 labs
• 4 penalty points 2 labs
• 8 penalty points 3 labs
• 12 penalty points 1 lab
• 16 penalty points 4 labs
• 2 PPP in 2008

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Labs in the PP Category