CP12222281

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Motivation for Innovation

• Steve Van Nurden
• Mayo Clinic Office of Intellectual Property

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Working at Mayo
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Mayo Clinic
Rochester,Minnesota
Scottsdale,Arizona
Jacksonville,Florida
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Motivation

• Make a commitment to practicing innovation
• This is a journey, not an event

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Innovation

• Innovation is the process that translates
  knowledge into economic growth and social
  well-being.
• It encompasses a series of scientific,
  technological, organizational, financial and
  commercial activities.

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Motivation for Innovation

• The unexpected, golden nuggets
• Failures as part of innovation
• Outside the mainstream
• An eye on industry and the marketplace
• Demographic Landscape
• We need a better process

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The unexpected, golden nuggets

• Always remember that this whole thing was
  started with a dream and a mouse.
• Walt Disney

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The unexpected, golden nuggets

• Radio frequency identification (RFID) to track
  and trace lab specimens

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Failures as part of innovation

• "I didnt fail the test, I just found 100 ways to
  do it wrong.
• Benjamin Franklin

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Failures as part of innovation

• Karvita Inc.
• From mesh to magnets
• If at first you dont succeed

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Degaussed Magnetized Steel Struts
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Outside the Mainstream

• Logic will get you from A to B. Imagination
  will take you anywhere.
• Albert Einstein

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Outside the Mainstream

• Mayo cardiologist publishes research in Neurology
  Journal
• The Editor of the Journal stated this is the
  first publication by a group of cardiologists in
  their journal

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An eye on industry and the marketplace

• Today, the only thing that is permanent is
  change.
• Charles H. Mayo, M.D.

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An eye on industry and the marketplace

• Personalized medicine
• Assure RX

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Demographic Landscape

• "In the conquering of serious diseases by
  surgical measures it is important that the
  operation itself should be as free from mortality
  as possible."
• Charles H. Mayo, M.D
• .

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Demographic Landscape

• Surgery on a beating heart NeoChord
• Does not require a sternotomy
• 1 day hospitalization vs. 7 day for OHS
• Can be done without cardiopulmonary bypass
• Prevents neurological damage
• Allows for a more efficient operation
• Replacement chordae sizing
• Shorter procedure
• Potential patient population of 1-2 million

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We need a better process

• If birds can glide for long periods of time,
  thenwhy cant I
• Orville Wright

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We need a better process

• Needle biopsies, difficulty due to normal patient
  breathing
• Interactive Breath Hold Control System - Mayo
  Clinic Medical Device

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What motivates you?

• Inspired by a friend

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Saving Lives Through Research

• Biomarkers for early stage diagnosis of
  pancreatic cancer in stool
• Development of small molecule inhibitors to treat
  pancreatic cancer
• Mining a library of compounds to look for
  inhibitors
• Using the discovery of high levels of Vav-1 in
  pancreatic cancer cells to compare against normal
  cells

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Motivation for Innovation

• Steve Van Nurden
• Mayo Clinic Office of Intellectual Property