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Good, Better, Best

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Live, attentuated viral vaccine, derived from Oka strain ... Zoster (Shingles) After Vaccination. Most occur among children. Not all are confirmed from virus ... – PowerPoint PPT presentation

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Title: Good, Better, Best


1
Good, Better,
Best!
  • Increasing Varicella Coverage ages 4-12

Carole Watson, RN, BSN Immunization Program
Manager Forsyth County Department of Public
Health 10/2/03
2
Varicella Age-Specific Incidence
Rate per 100,000 population. National Health
Interview Survey data, 1990-1994.
3
History of Varicella Vaccine
  • Live, attentuated viral vaccine, derived from
    Oka strain of varicella zoster virus (herpes
  • virus family)
  • Licensed in Japan Korea in 1988
  • Licensed in US in 1995 (Varivax)

4
Effectiveness of Varivax
  • Efficacy against infection 80-90
  • Efficacy against severe disease 95
  • Secondary bacterial (Staph or Strep) infections
    of skin lesions
  • CNS manifestations (aseptic meningitis,
    encephalitis, etc.)

5
9-yr-old with Staphylococcus aureus of varicella
lesions
6
Child with scleral lesions and bulbar
conjunctivitis
7
Use of Varivax
  • Routinely given at 12-18 mos. of age
  • Required for children born on or after
  • April 1, 2001 (given between 12 and 18 months of
    age)
  • Recommended for all susceptible children before
    their 13th birthday
  • (Susceptible no reliable history of disease
    and no history of vaccine)

8
SHOULD YOU GIVE VARIVAX IF
  • The parent is not sure if the child has had
    chickenpox disease?
  • There is an immunosuppressed person living in
    the home with the child?
  • The child is receiving an MMR today?
  • The child received an MMR 2 weeks ago?
  • There is a pregnant woman in the home?

9
Adverse Varivax Reactions
  • Injection site soreness, redness, swelling
  • Fever (usually from other illness)
  • Generalized varicella-like rash
  • 4-6 of recipients
  • Average of 5 lesions
  • Occurs within 3 wks. usually maculopapular
    (rather than vesicular)

10
Zoster (Shingles) After Vaccination
  • Most occur among children
  • Not all are confirmed from virus
  • All have been mild not associated with
    complications
  • Risk from wild virus 4-5 times higher than from
    vaccine virus

11
Total Varicella Doses Given at FCDPH (1999-2002)
12
Varicella Doses, ages 4-12, FCDPH (1999)
GOOD
13
Varicella Doses, ages 4-12, FCDPH (2000-2002)
BETTER
14
Varicella Doses, ages 4-12, FCDPH (1999-2002)
BEST?
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