Changes to the BME Minor

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The Bioengineering Experience at MIT the
Biology Requirement
17th NEEDHA Meeting, San Diego, March 17, 2001
Alan J Grodzinsky Director, MIT Center for
Biomedical Engineering Professor of Electrical,
Mechanical, Bioengineering EECS MechE Div
Bioengineering Environmental Health (BEH)
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Advances in Biomedical Engineering
Contributions to Clinical Practice Diagnosis,
Therapy Rehab

• 1790-1800 Galvani -- Volta
• 1900 - 1950 Electrical Properties of Tissues
  Cells
• WWII Ionizing Radiation ? Radiation
  Therapy
• 1960s-1970s Elec Mech Chem Physiology
• Medicine ? Dramatic
  advances in
• Health Care based on BME
• 1970s ? Diagnostics (CT, MRI, US.. Image
  analysis)

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BME is undergoing a major Ideological Change.
The fusion of engineering with molecular cell
biology is pushing the evolution of a new
engineering discipline termed Bioengineering to
tackle challenges in molecular and genomic
medicine.
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General Institute Requirements(MITs GIRs
1994)
? Humanities, Arts Social Sciences 8 ?
Science
5 ? 6 Math
(2)
Physics
(2) Chemistry

(1) Biology (7.01x)
0 ? 1 ? Resticted
Electives in Science Tech 3 ? 2 ? Laboratory
Requirement 1
Total
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General Institute Requirements

• Biology Requirement Introductory Biology
• Core material in biochemistry, genetics,
  molecular and cell biology
• Focus at the molecular level structure and
  regulation of genes structure and synthesis of
  proteins integration of protein into cells
  integration of cells into multicellular
  systems(the focus of MITs Bio Dept)
• Dramatic increase in Biology and ChemE student
  population, while EECS is still highest by far.
  

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Bioengineering Programs at Undergraduate Level

• UG Interdepartmental Minor in
• Biomedical Engineering
• Five-Year Combined SB/MEng

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The BME Undergrad MinorEducational Philosophy

• Builds on the foundation established by the
  students major program
• Merges engineering and biology
• Enables entry into
• The biomedical products or biotech industries
• Graduate school in bioengineering
• Medical school

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MIT Interdepartmental Minorin Biomedical
Engineering

• Science Core
• (1) 5.12 (Organic Chem)
• (2) 7.05 or 5.07 (Biochem)
• (5/6) 2 BME CORE subjects (cell, tissue, molec.
  eng., etc)
• (7) 1 BME Elective (from listed Core or
  Elective subjects)
• (from course 2, 3, 6, 10, 16, 22, BEH, or
  HST)
• (8) Plus Bio subject or BME Core or BME
  elective

Engineering Core (3) 18.03 (Diff. Eq.) (4)
Circuits, fluids, or systems.
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BME MINOR Current Enrollment by Major
40
30
Number of Students
20
10
0
Aero
Biology
Chemistry
ChemE
EECS
Material
MechE
NucE
Sc
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Doctoral Programs at MIT Involving Bioengineering

• Departments in School of Engineering
• Ph.D. thesis research in bioengineering
• Division of Bioengineering and Environmental
  Health (BEH)
• Ph.D. in Bioengineering
• Harvard-MIT Div of Health Sci and Technology
• Ph.D. in Speech and Hearing Sciences
• Ph.D. in Medical Engineering and Medical Physics
• Ph.D. in Radiological Sciences

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Key Features of Bioengineering Ph.D. Program in
BEH

• Emphasis on molecular and cellular phenomena
• -- integration of bio sciences with
  advanced engineering
• Integration of engineering disciplines
• electrical engineering and computer science
• chemical engineering
• mechanical engineering
• Diverse career paths academic or industrial
• molecular, cell tissue therapeutics, medical
  devices instrumentation, other

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BEH Ph.D. CURRICULUM

• Bioengineering Core (4)
• BEH.400 Perspectives in Biological Engineering
• BEH.410 Molecular, Cellular, and Tissue
  Biomechanics
• BEH.420 Biomolecular Kinetics and Cellular
  Dynamics
• BEH.430 Fields, Forces and Flows in Biological
  Systems
• Restricted Electives (6)
• Bioengineering (1) Biomaterials,
  instrumentation,
• bioinformatics computational biology
• Engineering Science (2) Core subjects in a
  traditional discipline
• Biological Science (3) Biochemistry, molecular
  or cell biology, one other

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5-Year BEH MEng inBiomedical Engineering

• A 5-year, combined SB/MEng program with SB in
  School of Engineering or Science
• For students interested in
• The biomedical products or biotech industries
• A medical degree
• Further graduate studies in bioengineering or
  medical engineering

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Curriculum for the 5-Year MEng Program

• Undergrad degree from an Eng. or Science
  department
• Grad one AY one summer
• BME Undergrad Minor Core Subjects
• BME Grad Core 66 units, 42 H-level Two from
• BEH.410J - Molecular, Cellular Tissue
  Biomechanics
• BEH.420J - Biomolecular Kinetics and Cellular
  Dynamics
• BEH.430J - Fields, Forces Flows in Biological
  Systems
• BME Electives (2 subjects from a list of over 30)
• Bioscience core (1bio subject beyond the SB)
• Thesis (24 unit minimum)

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CENTER for BIOMEDICAL ENGINEERINGOne of several
Interdepartmental Labs Interfacing Departmental
Faculty Student BioE Research

MISSION To foster research fusing Engineering
and Biology for Applications in Medicine and
Biology

• Interdisciplinary Faculty Research creates a
  training environment for a new generation of
  students/leaders in Bioengineering

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